| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L043521
BDB043521
|
BDBM50008162
COC(=O)[C@H](NC(=O)[C@H](Cc1ccccc1)NS(=O)(=O)N1CCOCC1)C(=O)N[C@@H](CC1CCCCC1)C(=O)C(F)(F)C(=O)NCCN1CCOCC1
|
C34H50F2N6O10S 772.869000 |
ILVIKHFAJWQSOQ-HZFUHODCSA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50008162
|
Local ready
Direct docking supported
|
|
E3L043522
BDB043522
|
BDBM50008520
CC(C)(C)S(=O)(=O)CC(Cc1ccccc1)C(=O)NC(Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
|
C33H52N4O9S 680.865000 |
SEGJVTDZQVOHPV-BGYFKOBFSA-N | P00797 | Renin |
BindingDB, PubChem
BindingDB:BDBM50008520; PubChem:CID44368301
|
Local ready
Direct docking supported
|
|
E3L043523
BDB043523
|
BDBM50008522
N[C@H]1CC[C@@H](C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(Cc2cnc[nH]2)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)CC1
|
C35H54N6O8 686.851000 |
CUROVAUDQZGVJM-UVGOGCJSSA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50008522
|
Local ready
Direct docking supported
|
|
E3L043524
BDB043524
|
BDBM50008524
CN(CCN(C)C(=O)N1CCOCC1)C(=O)O[C@@H](Cc1ccccc1)C(=O)NC(Cc1cnc[nH]1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
|
C38H59N7O11 789.928000 |
MOWGEQXIGWIIOA-SOZRXOLWSA-N | P00797 | Renin |
BindingDB
BindingDB:BDBM50008524
|
Local ready
Direct docking supported
|
|
E3L043525
BDB043525
|
AM-6761
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(CC(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C33H37Cl2FN2O5S2 695.706000 |
HNLHOKSDTBAERS-CWIPYCOQSA-N | O15151, Q00987 | E3 ubiquitin-protein ligase Mdm2, Protein Mdm4 |
BindingDB, PubChem
BindingDB:BDBM50008748; PubChem:CID73386675
|
Local ready
Direct docking supported
|
|
E3L043526
BDB043526
|
BDBM50008749
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H38Cl2N2O5S 657.660000 |
PNBIDSMJDDJULQ-JCUDBWTNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008749
|
Local ready
Direct docking supported
|
|
E3L043527
BDB043527
|
BDBM50008750
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2cc(C(=O)O)ccn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H38Cl2N2O5S 657.660000 |
GEDLWRDUBQVNGB-JCUDBWTNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008750
|
Local ready
Direct docking supported
|
|
E3L043528
BDB043528
|
BDBM50008751
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2nc(CC(=O)O)cs2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H38Cl2N2O5S2 677.716000 |
XCRGKBIGLYHHMI-HEBVPBOISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008751
|
Local ready
Direct docking supported
|
|
E3L043529
BDB043529
|
BDBM50008753
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H35Cl2N5O3S 592.593000 |
KENRSCUSWCVFPT-ZJTSJXPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008753; PubChem:CID90655374
|
Local ready
Direct docking supported
|
|
E3L043530
BDB043530
|
BDBM50008754
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(Cc2noc(=O)[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H35Cl2N3O5S 608.588000 |
YBMODFWQBWSTTG-FIULFVJVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008754; PubChem:CID136056460
|
Local ready
Direct docking supported
|
|
E3L043531
BDB043531
|
BDBM50008755
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)NS(=O)(=O)C(F)(F)F)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H35Cl2F3N2O6S2 699.641000 |
KVURUXGLNAWILE-ZJTSJXPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008755; PubChem:CID90655376
|
Local ready
Direct docking supported
|
|
E3L043532
BDB043532
|
BDBM50008756
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C30H35Cl2NO6S 608.584000 |
HKMNSIXDWLMKFA-JVUUKAHWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008756; PubChem:CID90655377
|
Local ready
Direct docking supported
|
|
E3L043533
BDB043533
|
BDBM50008758
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(=O)CO)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H37Cl2NO5S 582.590000 |
OCIDJOZAAORGQC-RRYSNUMESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008758; PubChem:CID90655378
|
Local ready
Direct docking supported
|
|
E3L043534
BDB043534
|
BDBM50008759
CC[C@@H](CS(=O)(=O)C(C)(C)C)N1C(=O)[C@@](C)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H36Cl2N2O4S 567.579000 |
LQFZONHTRLPWKM-ZJTSJXPUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008759; PubChem:CID90655379
|
Local ready
Direct docking supported
|
|
E3L043535
BDB043535
|
BDBM50008760
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H36Cl2N2O4S 579.590000 |
MANSWCXFKVIKPE-HIJQLYNKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008760; PubChem:CID90354304
|
Local ready
Direct docking supported
|
|
E3L043536
BDB043536
|
BDBM50008761
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CS(N)(=O)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H36Cl2N2O5S2 615.645000 |
OGTCBKWJBDPSAX-PAHOUZJPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008761; PubChem:CID90655380
|
Local ready
Direct docking supported
|
|
E3L043537
BDB043537
|
BDBM50008762
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CC[C@@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H42Cl2N2O6S 677.691000 |
VZZITKBMNYFVPR-OQZRLNFTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008762
|
Local ready
Direct docking supported
|
|
E3L043538
BDB043538
|
BDBM50008763
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)N2CC[C@H](C(=O)O)C2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H42Cl2N2O6S 677.691000 |
VZZITKBMNYFVPR-RHWDBWQKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008763
|
Local ready
Direct docking supported
|
|
E3L043539
BDB043539
|
BDBM50008764
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccccn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H38Cl2N2O3S 613.651000 |
UNKIPWCTGDLSKY-MMYUMUNASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008764; PubChem:CID90655383
|
Local ready
Direct docking supported
|
|
E3L043540
BDB043540
|
BDBM50008765
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccccc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H39Cl2NO3S 612.663000 |
AWJWXXHHLFWIPR-XCXSIRTKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008765; PubChem:CID90655384
|
Local ready
Direct docking supported
|