| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L043541
BDB043541
|
BDBM50008766
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)CO)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H38Cl2N2O5S2 677.716000 |
SYEJHQQRLZNDAL-GXAGMUTGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008766
|
Local ready
Direct docking supported
|
|
E3L043542
BDB043542
|
BDBM50008767
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2cccc(C(=O)O)n2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C34H38Cl2N2O5S 657.660000 |
KXFYXOPMGHFDFT-XOEHLWFXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008767
|
Local ready
Direct docking supported
|
|
E3L043543
BDB043543
|
BDBM50008769
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C34H37Cl2FN2O5S 675.650000 |
FZOPKODHJVPVBM-FRCGYQLOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008769
|
Local ready
Direct docking supported
|
|
E3L043544
BDB043544
|
BDBM50008770
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(CC(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C35H40Cl2N2O5S 671.687000 |
HDEJTMINIOUGHU-PZAYWHPNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008770
|
Local ready
Direct docking supported
|
|
E3L043545
BDB043545
|
BDBM50008771
CC(C)(C(=O)O)c1ccc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)nc1
|
C37H44Cl2N2O5S 699.741000 |
ZBBQRZDTFXLMBM-VIFXNLTHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008771
|
Local ready
Direct docking supported
|
|
E3L043546
BDB043546
|
BDBM50008772
Cc1nc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ccc1C(=O)O
|
C35H40Cl2N2O5S 671.687000 |
IJGOXKRIKNRLNK-WLDYPGBFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008772
|
Local ready
Direct docking supported
|
|
E3L043547
BDB043547
|
BDBM50008773
Cc1cc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)ncc1C(=O)O
|
C35H40Cl2N2O5S 671.687000 |
FGEFVHVLJFIHGW-WZZDHPINSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008773
|
Local ready
Direct docking supported
|
|
E3L043548
BDB043548
|
BDBM50008774
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H37Cl2N3O5S 658.648000 |
NMPHGOIIKGHVBC-UNVYQVKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008774
|
Local ready
Direct docking supported
|
|
E3L043549
BDB043549
|
BDBM50008775
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C33H36Cl2FN3O5S 676.638000 |
IRXHRNNYERLRSZ-BUXNRPJVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008775
|
Local ready
Direct docking supported
|
|
E3L043550
BDB043550
|
BDBM50008776
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2cnc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H37Cl2N3O5S 658.648000 |
ZUQXBAOZHMDZPP-SQBYSBBASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008776
|
Local ready
Direct docking supported
|
|
E3L043551
BDB043551
|
BDBM50008777
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ccc(C(=O)O)cc2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C35H39Cl2NO5S 656.672000 |
NCCRYPWLIXANJL-WLDYPGBFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008777; PubChem:CID90655395
|
Local ready
Direct docking supported
|
|
E3L043552
BDB043552
|
BDBM50008778
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cn2cc(C(=O)O)cn2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C32H37Cl2N3O5S 646.637000 |
URNIBHZXTBEEAS-RBUURGHLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008778
|
Local ready
Direct docking supported
|
|
E3L043553
BDB043553
|
BDBM50008804
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2nc(C(=O)O)cs2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C32H36Cl2N2O5S2 663.689000 |
JKNAPKZDFAXRMN-JTQASVMASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008804
|
Local ready
Direct docking supported
|
|
E3L043554
BDB043554
|
BDBM50008806
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C32H36Cl2N2O5S2 663.689000 |
IMXWFPHEMCUNGD-LIYLGVFKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008806
|
Local ready
Direct docking supported
|
|
E3L043555
BDB043555
|
BDBM50008808
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C32H35Cl2FN2O5S2 681.679000 |
JXPSJUQXEZZOEN-AJRUUFPASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008808
|
Local ready
Direct docking supported
|
|
E3L043556
BDB043556
|
BDBM50008809
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2nccs2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C31H35Cl2FN2O3S2 637.670000 |
BRLUWZXCWJPMRO-LQAFYMSYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50008809; PubChem:CID90655400
|
Local ready
Direct docking supported
|
|
E3L043557
BDB043557
|
BDBM50008810
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(CC(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C33H38Cl2N2O5S2 677.716000 |
FRFAHFNWZGNPRP-HEBVPBOISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008810
|
Local ready
Direct docking supported
|
|
E3L043558
BDB043558
|
BDBM50008811
CC(C)(C(=O)O)c1cnc(C[C@@]2(C)C[C@H](c3cccc(Cl)c3)[C@@H](c3ccc(Cl)cc3)N([C@H](CS(=O)(=O)C(C)(C)C)C3CC3)C2=O)s1
|
C35H42Cl2N2O5S2 705.770000 |
GAWODCRVYATSKO-KFBOFYSKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008811
|
Local ready
Direct docking supported
|
|
E3L043559
BDB043559
|
BDBM50008812
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C3(C(=O)O)CC3)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C35H40Cl2N2O5S2 703.754000 |
HHQVGGDYUPWBRZ-ZVFFISPPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008812
|
Local ready
Direct docking supported
|
|
E3L043560
BDB043560
|
BDBM50008813
CC(C)(C)S(=O)(=O)C[C@H](C1CC1)N1C(=O)[C@@](C)(Cc2ncc(C(F)C(=O)O)s2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)c(F)c1
|
C33H36Cl2F2N2O5S2 713.696000 |
GETYJEOBBNSQJM-PAFYYSOCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50008813
|
Local ready
Direct docking supported
|