| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L055881
BDB055881
|
BDBM50432648
CN1C(=O)CO[C@@H](c2ccc(Cl)cc2)[C@H]1c1cccc(Cl)c1
|
C17H15Cl2NO2 336.218000 |
HLEJTSIQXVTYDP-SJORKVTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432648; PubChem:CID71663527
|
Local ready
Direct docking supported
|
|
E3L055882
BDB055882
|
BDBM50432649
O=C1CO[C@@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1
|
C20H19Cl2NO2 376.283000 |
USNQYGDSTBFBSK-UXHICEINSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432649; PubChem:CID71663526
|
Local ready
Direct docking supported
|
|
E3L055883
BDB055883
|
BDBM50432650
CN1C(=O)CO[C@@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C17H15Cl2NO2 336.218000 |
ZUYDNBDMQAEZPD-SJORKVTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432650; PubChem:CID71663525
|
Local ready
Direct docking supported
|
|
E3L055884
BDB055884
|
BDBM50432651
COc1cccc2c1C1=C([C@H](c3ccc(Br)cc3)n3ncnc3N1C)[C@@H](c1ccc(Br)cc1)O2
|
C26H20Br2N4O2 580.280000 |
CBAILBZVEPFBDC-UKILVPOCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432651; PubChem:CID44549764
|
Local ready
Direct docking supported
|
|
E3L055885
BDB055885
|
BDBM50432652
CC[C@@H](CO)N1C(=O)[C@H](CC(=O)O)O[C@@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C22H23Cl2NO5 452.334000 |
GOJFTLJDUNFYCJ-MMKMLUHNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432652; PubChem:CID71305074
|
Local ready
Direct docking supported
|
|
E3L055886
BDB055886
|
BDBM50432653
COc1cccc(C[C@@H]2O[C@@H](c3ccc(Br)cc3)[C@@H](c3ccc(Br)cc3)N(C)C2=O)c1
|
C25H23Br2NO3 545.271000 |
FCOPQZKTHYVUEK-VXNXHJTFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432653; PubChem:CID71663336
|
Local ready
Direct docking supported
|
|
E3L055887
BDB055887
|
BDBM50432654
COc1ccc(C[C@@H]2O[C@@H](c3ccc(Br)cc3)[C@@H](c3ccc(Br)cc3)N(C)C2=O)cc1
|
C25H23Br2NO3 545.271000 |
JQFPMGMYKYPPLI-VXNXHJTFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432654; PubChem:CID71663335
|
Local ready
Direct docking supported
|
|
E3L055888
BDB055888
|
BDBM50432655
CN1C(=O)[C@H](Cc2ccc(F)cc2)O[C@@H](c2ccc(Br)cc2)[C@H]1c1ccc(Br)cc1
|
C24H20Br2FNO2 533.235000 |
ZOPUXVMFTFLAOX-ZRBLBEILSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432655; PubChem:CID71663334
|
Local ready
Direct docking supported
|
|
E3L055889
BDB055889
|
BDBM50432656
CN1C(=O)[C@H](Cc2ccc(Br)cc2)O[C@@H](c2ccc(Br)cc2)[C@H]1c1ccc(Br)cc1
|
C24H20Br3NO2 594.141000 |
RHWGELPEQKFUHE-ZRBLBEILSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432656; PubChem:CID71663333
|
Local ready
Direct docking supported
|
|
E3L055890
BDB055890
|
BDBM50432657
CN1C(=O)[C@@H](Cc2ccccc2)O[C@H](c2ccc(Br)cc2)[C@@H]1c1ccc(Br)cc1
|
C24H21Br2NO2 515.245000 |
YYVYIVSNIAMIER-XPWALMASSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432657; PubChem:CID71663332
|
Local ready
Direct docking supported
|
|
E3L055891
BDB055891
|
BDBM50432658
CN1C(=O)[C@H](Cc2ccccc2)O[C@@H](c2ccc(Br)cc2)[C@H]1c1ccc(Br)cc1
|
C24H21Br2NO2 515.245000 |
YYVYIVSNIAMIER-ZRBLBEILSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432658; PubChem:CID71305070
|
Local ready
Direct docking supported
|
|
E3L055892
BDB055892
|
BDBM50432659
CN1C(=O)[C@H](Cc2ccccc2)O[C@@H](c2ccc(Cl)cc2)[C@H]1c1ccc(Cl)cc1
|
C24H21Cl2NO2 426.343000 |
NFFXQTHZDQEVMP-ZRBLBEILSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432659; PubChem:CID71305071
|
Local ready
Direct docking supported
|
|
E3L055893
BDB055893
|
BDBM50432660
CN1C[C@H](Cc2ccccc2)O[C@@H](c2ccc(Br)cc2)[C@H]1c1ccc(Br)cc1
|
C24H23Br2NO 501.262000 |
XHMBUTLIIFQBNB-VXNXHJTFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432660; PubChem:CID71663151
|
Local ready
Direct docking supported
|
|
E3L055894
BDB055894
|
(5R,6S)-5,6-bis(4-bromophenyl)-4-methylmorpholin-3-one
CN1C(=O)CO[C@@H](c2ccc(Br)cc2)[C@H]1c1ccc(Br)cc1
|
C17H15Br2NO2 425.120000 |
OUTBUVLNDIYGFF-SJORKVTESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432661; PubChem:CID71663150
|
Local ready
Direct docking supported
|
|
E3L055895
BDB055895
|
BDBM50432662
CC(C)N[C@@H]1CC[C@H](c2ccc(Cl)cc2)[C@H](c2ccc(Cl)cc2)C1
|
C21H25Cl2N 362.344000 |
GYVSDGRZPBXQQE-NJYVYQBISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432662; PubChem:CID71717128
|
Local ready
Direct docking supported
|
|
E3L055896
BDB055896
|
BDBM50432663
CC(C)(C)OC(=O)N1CC(=O)N[C@H](c2ccc(Br)cc2)[C@@H]1c1ccc(Br)cc1
|
C21H22Br2N2O3 510.226000 |
OKONUZXONDSDEG-MOPGFXCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432663; PubChem:CID71720163
|
Local ready
Direct docking supported
|
|
E3L055897
BDB055897
|
BDBM50432664
COc1ccc([C@H]2CC(=O)C=C(c3ccc(Cl)cc3)[C@@H]2c2ccc(Cl)cc2)cc1OC
|
C26H22Cl2O3 453.365000 |
UAGBKVIPZKMMLW-BVAGGSTKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432664; PubChem:CID71717752
|
Local ready
Direct docking supported
|
|
E3L055898
BDB055898
|
BDBM50432665
CC(C)(C)C[C@@H]1N[C@@H](C(=O)NCCN2CCOCC2)[C@H](c2cccc(Cl)c2F)[C@]12C(=O)Nc1cc(Cl)ccc12
|
C29H35Cl2FN4O3 577.528000 |
YTBYOWZWBDYLQF-WSQBEXMKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50432665; PubChem:CID69498032
|
Local ready
Direct docking supported
|
|
E3L055899
BDB055899
|
BDBM50432753
CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)CCc2ccc(CCC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
|
C66H80N10O8 1141.428000 |
MBYKTLFFZHKOJM-JLQINWGESA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 3, Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP |
BindingDB
BindingDB:BDBM50432753
|
Local ready
Direct docking supported
|
|
E3L055900
BDB055900
|
BDBM50432754
CN[C@@H](C)C(=O)N[C@H]1CN(C(=O)Cc2ccc(CC(=O)N3CC[C@H]4CC[C@@H](C(=O)NC(c5ccccc5)c5ccccc5)N4C(=O)[C@@H](NC(=O)[C@H](C)NC)C3)cc2)CC[C@H]2CC[C@@H](C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O
|
C64H76N10O8 1113.374000 |
HTZHOCIWGSKKLL-SQHFRGFLSA-N | P98170, Q13489, Q13490 | Baculoviral IAP repeat-containing protein 3, Baculoviral IAP repeat-containing protein 2, E3 ubiquitin-protein ligase XIAP |
BindingDB
BindingDB:BDBM50432754
|
Local ready
Direct docking supported
|