| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L060621
BDB060621
|
BDBM50562005
C[C@@H]1COCCN1c1nc(-c2cnc(N)s2)nc2c1C[C@@H]1COCCN21
|
C17H22N6O2S 374.470000 |
DZIVLAHVAHIFES-GHMZBOCLSA-N | Q9BVC4 | Target of rapamycin complex subunit LST8 |
BindingDB, PubChem
BindingDB:BDBM50562005; PubChem:CID162660791
|
Local ready
Direct docking supported
|
|
E3L060622
BDB060622
|
BDBM50562006
C[C@@H]1COCCN1c1nc(-c2cnc(N)cc2C(F)F)nc2c1C[C@@H]1COCCN21
|
C20H24F2N6O2 418.448000 |
NFISZJMWQXGLIR-VXGBXAGGSA-N | Q9BVC4 | Target of rapamycin complex subunit LST8 |
BindingDB, PubChem
BindingDB:BDBM50562006; PubChem:CID162645758
|
Local ready
Direct docking supported
|
|
E3L060623
BDB060623
|
BDBM50562007
C[C@@H]1COCCN1c1nc(-c2cnc(N)nc2C(F)F)nc2c1C[C@@H]1COCCN21
|
C19H23F2N7O2 419.436000 |
XXVSQSOIIVGFNA-GHMZBOCLSA-N | Q9BVC4 | Target of rapamycin complex subunit LST8 |
BindingDB, PubChem
BindingDB:BDBM50562007; PubChem:CID162652065
|
Local ready
Direct docking supported
|
|
E3L060624
BDB060624
|
BDBM50562008
C[C@@H]1COCCN1c1nc(-c2cnc(N)cc2C(F)(F)F)nc2c1C[C@@H]1COCCN21
|
C20H23F3N6O2 436.438000 |
ICFCLKXLAFXQOP-VXGBXAGGSA-N | Q9BVC4 | Target of rapamycin complex subunit LST8 |
BindingDB, PubChem
BindingDB:BDBM50562008; PubChem:CID162654516
|
Local ready
Direct docking supported
|
|
E3L060625
BDB060625
|
BDBM50562009
C[C@@H]1COCCN1c1nc(-c2cnc(N)nc2C(F)(F)F)nc2c1C[C@@H]1COCCN21
|
C19H22F3N7O2 437.426000 |
GBPUNAJUBCBVCM-GHMZBOCLSA-N | Q9BVC4 | Target of rapamycin complex subunit LST8 |
BindingDB, PubChem
BindingDB:BDBM50562009; PubChem:CID162648518
|
Local ready
Direct docking supported
|
|
E3L060626
BDB060626
|
BDBM50562010
C[C@@H]1COCCN1c1nc(-c2cnc(N)c(C(F)(F)F)c2)nc2c1C[C@@H]1COCCN21
|
C20H23F3N6O2 436.438000 |
RMGRYVPJEBKCAS-DGCLKSJQSA-N | Q9BVC4 | Target of rapamycin complex subunit LST8 |
BindingDB, PubChem
BindingDB:BDBM50562010; PubChem:CID162657162
|
Local ready
Direct docking supported
|
|
E3L060627
BDB060627
|
BDBM50562129
COc1ccc(CCc2nc3cc(-c4c(C)noc4C)ccc3n2CCN2CCOCC2)cc1Cl
|
C27H31ClN4O3 495.023000 |
BMFWCARUVZTJGG-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50562129; PubChem:CID162654369
|
Local ready
Direct docking supported
|
|
E3L060628
BDB060628
|
BDBM50562130
COC(=O)N1CCCc2cc(NC(=O)C3CC=CCC3C(=O)O)ccc21
|
C19H22N2O5 358.394000 |
KPFUFQIEFZZIBO-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50562130; PubChem:CID5312017
|
Local ready
Direct docking supported
|
|
E3L060629
BDB060629
|
BDBM50562131
Cc1cc2c(c(C(=O)NCCCN3CCCc4ccccc43)c1)N[C@H](C)C(=O)N2
|
C23H28N4O2 392.503000 |
QBIYZYWEQWBMAX-MRXNPFEDSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50562131; PubChem:CID162652607
|
Local ready
Direct docking supported
|
|
E3L060630
BDB060630
|
BDBM50562132
COc1ccc2c(c1)N(CCCNC(=O)c1cc(C)cc3c1N[C@H](C)C(=O)N3)CCC2
|
C24H30N4O3 422.529000 |
UXOXZQLQJWZVRM-MRXNPFEDSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50562132; PubChem:CID162670656
|
Local ready
Direct docking supported
|
|
E3L060631
BDB060631
|
BDBM50562133
CCN(CC)CCCC(C)NCc1nn2c(-c3ccccc3)nnc2s1
|
C19H28N6S 372.542000 |
VKWQTYSHJWGMAZ-UHFFFAOYSA-N | Q92793 | CREB-binding protein |
BindingDB, PubChem
BindingDB:BDBM50562133; PubChem:CID162656207
|
Local ready
Direct docking supported
|
|
E3L060632
BDB060632
|
BDBM50562134
CCNC(=O)c1ccc2c(C(=O)[C@H](NC[C@@H](C)c3ccc(C#N)cc3)c3ccccc3)c[nH]c2c1
|
C29H28N4O2 464.569000 |
QDOIWXLZWGTZOU-XHCCPWGMSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50562134; PubChem:CID156132148
|
Local ready
Direct docking supported
|
|
E3L060633
BDB060633
|
BDBM50562135
COc1cc2c(cc1OC)C1Cc3cc(O)c(O)cc3NC1CC2
|
C19H21NO4 327.380000 |
MUAOWZOXUPYUNB-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50562135; PubChem:CID162658719
|
Local ready
Direct docking supported
|
|
E3L060634
BDB060634
|
Venenatine
COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cccc(OC)c5c4CCN3C[C@H]2CC[C@H]1O
|
C22H28N2O4 384.476000 |
WMMZYEBFJWWUJX-YCSGKXEJSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50562136; PubChem:CID73061
|
Local ready
Direct docking supported
|
|
E3L060635
BDB060635
|
BDBM50562137
CC(=O)N[C@@H](CCCCNC(=O)CSCCNC(=O)[C@H](O)CCOP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3cncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)C(N)=O
|
C26H43N8O18P3S 880.657000 |
KISQSMZZUCEFRC-QEBMULIISA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM50562137
|
Local ready
Direct docking supported
|
|
E3L060636
BDB060636
|
BDBM50562523
O=C1C=CC2(C=C1)OCC(=O)N2c1nc(-c2cccc3ccccc23)nn1-c1ccccc1
|
C26H18N4O3 434.455000 |
NSWXPDNYWQZXRX-UHFFFAOYSA-N | O14965 | Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM50562523; PubChem:CID162655252
|
Local ready
Direct docking supported
|
|
E3L060637
BDB060637
|
BDBM50562607
CN(C)[C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
|
C24H34N4O2S 442.629000 |
VEABDKBNQNHHCB-RPWUZVMVSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50562607; PubChem:CID123132214
|
Local ready
Direct docking supported
|
|
E3L060638
BDB060638
|
BDBM50562608
CN(C)[C@H]1CN(C2CCc3cccc(F)c32)C[C@@H]1c1cn(C)c2ccccc12
|
C24H28FN3 377.507000 |
XAWMNFFOVCNWGF-QREQTRJTSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50562608; PubChem:CID132085664
|
Local ready
Direct docking supported
|
|
E3L060639
BDB060639
|
PROTAC EED degrader-2
Cc1nc(CCC(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(-c3scnc3C)cc2)C(C)(C)C)ccc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cnnc12
|
C50H58FN11O6S 960.150000 |
CQSOTYMFUWTIIR-HUSBZTEESA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50562610; PubChem:CID145925664
|
Local ready
Direct docking supported
|
|
E3L060640
BDB060640
|
PROTAC EED degrader-1
Cc1nc(CCC(=O)NCCOc2ccc(OCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(-c4scnc4C)cc3)C(C)(C)C)cc2)ccc1-c1cnc(NCc2c(F)ccc3c2CCO3)n2cnnc12
|
C55H60FN11O8S 1054.219000 |
FSFJUWLIBSALJI-FENRPDQVSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM50562611; PubChem:CID145925663
|
Local ready
Direct docking supported
|