| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L062661
BDB062661
|
BDBM50605114
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H39Cl2F2N3O4 710.649000 |
BLZIAGOKOYYYPM-HYPAZGOZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605114
|
Local ready
Direct docking supported
|
|
E3L062662
BDB062662
|
BDBM50605115
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccc2O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H39Cl2F2N3O5 726.648000 |
BOFDYYYDRTUPTP-HYPAZGOZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605115
|
Local ready
Direct docking supported
|
|
E3L062663
BDB062663
|
BDBM50605116
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cccc(O)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H39Cl2F2N3O5 726.648000 |
QVLVXOHPVNJAAP-HYPAZGOZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605116
|
Local ready
Direct docking supported
|
|
E3L062664
BDB062664
|
BDBM50605117
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccc(O)cc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H39Cl2F2N3O5 726.648000 |
KKSWCPFEKSWJCE-HYPAZGOZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605117
|
Local ready
Direct docking supported
|
|
E3L062665
BDB062665
|
BDBM50605118
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccc2C(=O)O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C39H39Cl2F2N3O6 754.658000 |
VOMKLSFZTLIXHR-FCTXCRTPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605118
|
Local ready
Direct docking supported
|
|
E3L062666
BDB062666
|
BDBM50605119
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cccc(C(=O)O)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C39H39Cl2F2N3O6 754.658000 |
ADZRQNWWLGEVAO-FCTXCRTPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605119
|
Local ready
Direct docking supported
|
|
E3L062667
BDB062667
|
BDBM50605120
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccc(C(=O)O)cc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C39H39Cl2F2N3O6 754.658000 |
NIIUFEVRFCDQDO-FCTXCRTPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605120
|
Local ready
Direct docking supported
|
|
E3L062668
BDB062668
|
BDBM50605121
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccccn2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C37H38Cl2F2N4O4 711.637000 |
MKFAZOWTXPCVFJ-GXFZAZKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605121
|
Local ready
Direct docking supported
|
|
E3L062669
BDB062669
|
BDBM50605122
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cccnc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C37H38Cl2F2N4O4 711.637000 |
SBKNMMOQCPQLRA-GXFZAZKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605122
|
Local ready
Direct docking supported
|
|
E3L062670
BDB062670
|
BDBM50605123
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2ccncc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C37H38Cl2F2N4O4 711.637000 |
UBACXUKBTJKWLY-GXFZAZKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605123
|
Local ready
Direct docking supported
|
|
E3L062671
BDB062671
|
BDBM50605124
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cnn(C)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C36H39Cl2F2N5O4 714.641000 |
HAIMFHHEIBGVAV-CBOGTRIESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605124
|
Local ready
Direct docking supported
|
|
E3L062672
BDB062672
|
BDBM50605125
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCc2cnc[nH]2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C35H37Cl2F2N5O4 700.614000 |
RDDBHCDHHFFBJD-JNHBBQSGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605125
|
Local ready
Direct docking supported
|
|
E3L062673
BDB062673
|
BDBM50605126
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCC2CCNCC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C37H44Cl2F2N4O4 717.685000 |
XJXDSLJECXYDEY-GXFZAZKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605126
|
Local ready
Direct docking supported
|
|
E3L062674
BDB062674
|
BDBM50605127
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNCC2CCOCC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C37H43Cl2F2N3O5 718.669000 |
VWRABQZPIGPPKS-GXFZAZKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605127
|
Local ready
Direct docking supported
|
|
E3L062675
BDB062675
|
BDBM50605128
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC2CCN(C)CC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C37H44Cl2F2N4O4 717.685000 |
WDXJLXZGEZCTNL-GXFZAZKKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605128
|
Local ready
Direct docking supported
|
|
E3L062676
BDB062676
|
BDBM50605129
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC2CCOCC2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C36H41Cl2F2N3O5 704.642000 |
FUJXTBWSALIBRY-CBOGTRIESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605129
|
Local ready
Direct docking supported
|
|
E3L062677
BDB062677
|
BDBM50605130
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC(=O)c2ccccc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H37Cl2F2N3O5 724.632000 |
CHNAPUBHXDSXOI-QXVSIQMFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605130
|
Local ready
Direct docking supported
|
|
E3L062678
BDB062678
|
BDBM50605131
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNC(=O)c2ccc(C(=O)O)cc2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C39H37Cl2F2N3O7 768.641000 |
XHTQFHABLLMSJN-CBWRIEIJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605131
|
Local ready
Direct docking supported
|
|
E3L062679
BDB062679
|
BDBM50605132
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNS(=O)(=O)c2ccccc2C(=O)O)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H37Cl2F2N3O8S 804.696000 |
ZTQHPSFCZJJGAD-QXVSIQMFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605132
|
Local ready
Direct docking supported
|
|
E3L062680
BDB062680
|
BDBM50605133
COc1cc(C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](CNS(=O)(=O)c2cccc(C(=O)O)c2)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H37Cl2F2N3O8S 804.696000 |
YVJRINPRHWGEEN-QXVSIQMFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM50605133
|
Local ready
Direct docking supported
|