| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L063561
BDB063561
|
BDBM50622010
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1cc(C(=O)c2ccccc2C)c[nH]1
|
C24H19N3O4 413.433000 |
ICKFHFUEGODDPY-MTJSOVHGSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50622010; PubChem:CID172455412
|
Local ready
Direct docking supported
|
|
E3L063562
BDB063562
|
BDBM50622011
CC(C)C1=NN(c2ccc(C(=O)O)cc2)C(=O)C1Cc1cc(C(=O)c2ccccc2[N+](=O)[O-])c[nH]1
|
C25H22N4O6 474.473000 |
MPPGNUPHQUKJHF-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50622011; PubChem:CID172446594
|
Local ready
Direct docking supported
|
|
E3L063563
BDB063563
|
BDBM50622013
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1ccco1
|
C16H12N2O4 296.282000 |
MVPIRFIRHBPBTQ-ZROIWOOFSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50622013; PubChem:CID5343927
|
Local ready
Direct docking supported
|
|
E3L063564
BDB063564
|
BDBM50622014
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1cccs1
|
C16H12N2O3S 312.350000 |
PUKRTSOVAYQRPV-ZROIWOOFSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50622014; PubChem:CID5343991
|
Local ready
Direct docking supported
|
|
E3L063565
BDB063565
|
BDBM50622018
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1c[nH]cn1
|
C15H12N4O3 296.286000 |
BUBZNIIVLDDSLY-MLPAPPSSSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM50622018
|
Local ready
Direct docking supported
|
|
E3L063566
BDB063566
|
BDBM50622019
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1cc2ccccc2[nH]1
|
C20H15N3O3 345.358000 |
NTHZGYUPGDCONC-BOPFTXTBSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM50622019
|
Local ready
Direct docking supported
|
|
E3L063567
BDB063567
|
BDBM50622020
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1c[nH]c2ccccc12
|
C20H15N3O3 345.358000 |
MYWPOPCUGRJXFC-YVLHZVERSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM50622020
|
Local ready
Direct docking supported
|
|
E3L063568
BDB063568
|
BDBM50622021
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1cccn1C
|
C17H15N3O3 309.325000 |
OXIDWSAFNKKQPK-GDNBJRDFSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50622021; PubChem:CID172458539
|
Local ready
Direct docking supported
|
|
E3L063569
BDB063569
|
BDBM50622022
CC1=NN(c2ccc(C(=O)O)cc2)C(=O)/C1=C\c1cccn1-c1ccccc1
|
C22H17N3O3 371.396000 |
GCIXFKDHTNXJOB-ZHZULCJRSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM50622022; PubChem:CID172456079
|
Local ready
Direct docking supported
|
|
E3L063570
BDB063570
|
BDBM50622267
C[C@H]1CN(C(=O)CNc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)CCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CC(C)(C)C6)C4=O)c3CO)cn(C)c2=O)nc1
|
C49H51N11O8 922.016000 |
DGDYTCIJBXSVPQ-XLYAUNJQSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50622267
|
Local ready
Direct docking supported
|
|
E3L063571
BDB063571
|
BDBM50622268
C[C@H]1CN(C(=O)c2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)CCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CC(C)(C)C6)C4=O)c3CO)cn(C)c2=O)nc1
|
C48H48N10O8 892.974000 |
TZJCAGSJIMIXFS-HJYWNDIWSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50622268
|
Local ready
Direct docking supported
|
|
E3L063572
BDB063572
|
BDBM50622269
C[C@H]1CN(C(=O)CCCCCCCCCCCNc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)CCN1c1ccc(Nc2cc(-c3ccnc(N4CCn5c(cc6c5CC(C)(C)C6)C4=O)c3CO)cn(C)c2=O)nc1
|
C59H71N11O8 1062.286000 |
HYZMVIWTOQSXRR-YLKGYVPLSA-N | Q96SW2 | Protein cereblon |
BindingDB
BindingDB:BDBM50622269
|
Local ready
Direct docking supported
|
|
E3L063573
BDB063573
|
Bbddl2059
C=CC(=O)NCc1cc(C(=O)NCc2c(SC)cc(C)[nH]c2=O)c(C)c(N(CC)C2CCOCC2)c1
|
C27H36N4O4S 512.676000 |
BKTRXKQBQKZJJS-UHFFFAOYSA-N | O96028, Q03164, Q96L73 | Histone-lysine N-methyltransferase 2A, Histone-lysine N-methyltransferase NSD2, Histone-lysine N-methyltransferase, H3 lysine-36 specific |
BindingDB, PubChem
BindingDB:BDBM50622285; PubChem:CID156784037
|
Local ready
Direct docking supported
|
|
E3L063574
BDB063574
|
Skp2 inhibitor 1
O=C(CCl)NC1CCN(c2cnc(-c3ccccc3)c(-c3ccccc3)n2)CC1
|
C23H23ClN4O 406.917000 |
MKWLNXUIWPRODH-UHFFFAOYSA-N | Q13309 | S-phase kinase-associated protein 2 |
BindingDB, PubChem
BindingDB:BDBM50622313; PubChem:CID162718203
|
Local ready
Direct docking supported
|
|
E3L063575
BDB063575
|
GSK-3 inhibitor 3
N#Cc1ccc(Nc2nccc(C(=O)Nc3cnccc3-c3ccc(F)cc3)n2)cc1
|
C23H15FN6O 410.412000 |
QLWFPXXGZGCHFQ-UHFFFAOYSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM50622457; PubChem:CID134556469
|
Local ready
Direct docking supported
|
|
E3L063576
BDB063576
|
GSK-3 inhibitor 4
O=C(Nc1cnccc1-c1ccc(F)cc1)c1ccnc(Nc2ccc(F)cc2)n1
|
C22H15F2N5O 403.392000 |
UWQKULXATKCNBV-UHFFFAOYSA-N | P51617 | Interleukin-1 receptor-associated kinase 1 |
BindingDB, PubChem
BindingDB:BDBM50622458; PubChem:CID134556675
|
Local ready
Direct docking supported
|
|
E3L063577
BDB063577
|
BDBM50622494
Cc1cc(CN2C(=O)CN(c3cccc(C(F)(F)F)c3)C2=O)cc(C)c1OC(C)(C)C(=O)O
|
C23H23F3N2O5 464.440000 |
AGUYCCKOLIKFIG-UHFFFAOYSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM50622494; PubChem:CID169794695
|
Local ready
Direct docking supported
|
|
E3L063578
BDB063578
|
BDBM50622495
Cc1cc(CN2C(=O)CN(c3ccc(C(F)(F)F)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O
|
C23H23F3N2O5 464.440000 |
BIIFAYFKMQRXPQ-UHFFFAOYSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM50622495; PubChem:CID168477242
|
Local ready
Direct docking supported
|
|
E3L063579
BDB063579
|
BDBM50622496
Cc1cc(CN2C(=O)CN(c3ccc(OC(F)(F)F)cc3)C2=O)cc(C)c1OC(C)(C)C(=O)O
|
C23H23F3N2O6 480.439000 |
QQTFNQJWRWAZKZ-UHFFFAOYSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM50622496; PubChem:CID169748316
|
Local ready
Direct docking supported
|
|
E3L063580
BDB063580
|
BDBM50622497
CC(C)(Oc1c(Br)cc(CN2C(=O)CN(c3ccc(C(F)(F)F)cc3)C2=O)cc1Br)C(=O)O
|
C21H17Br2F3N2O5 594.178000 |
OFUSDBKUMIIORB-UHFFFAOYSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma |
BindingDB, PubChem
BindingDB:BDBM50622497; PubChem:CID169748396
|
Local ready
Direct docking supported
|