| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L063721
BDB063721
|
BDBM50626211
C=CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)c3ccc(C(=O)OC)o3)[C@H]2SC1
|
C16H14N2O7S 378.362000 |
GFJULHYFTOFSBW-QMTHXVAHSA-N | O43791 | Speckle-type POZ protein |
BindingDB, PubChem
BindingDB:BDBM50626211; PubChem:CID172448661
|
Local ready
Direct docking supported
|
|
E3L063722
BDB063722
|
BDBM50626723
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(-c3ccccc3)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C34H30N2O10S2 690.752000 |
IHLRKIWSZPXPKS-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626723; PubChem:CID154998057
|
Local ready
Direct docking supported
|
|
E3L063723
BDB063723
|
Nrf2 activator-7
COc1ccc(-c2cc(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc3c2N(CC(=O)O)S(=O)(=O)c2ccc(OC)cc2)cc1
|
C35H32N2O11S2 720.778000 |
FYOHBNAOGGBOGT-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626724; PubChem:CID154998133
|
Local ready
Direct docking supported
|
|
E3L063724
BDB063724
|
BDBM50626725
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(-c3ccc(C#N)cc3)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C35H29N3O10S2 715.762000 |
ULCMDORLNFVULD-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626725; PubChem:CID154997956
|
Local ready
Direct docking supported
|
|
E3L063725
BDB063725
|
BDBM50626726
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(-c3ccc(N4C(=O)c5ccccc5C4=O)cc3)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C42H33N3O12S2 835.869000 |
TZTAISDLASISEW-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626726; PubChem:CID172448230
|
Local ready
Direct docking supported
|
|
E3L063726
BDB063726
|
BDBM50626727
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(Sc3ccccc3)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C34H30N2O10S3 722.819000 |
OLLUZVHWYUYFAK-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626727; PubChem:CID154653370
|
Local ready
Direct docking supported
|
|
E3L063727
BDB063727
|
Keap1-Nrf2-IN-15
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(CCCN3C(=O)c4ccccc4C3=O)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C39H35N3O12S2 801.852000 |
NRGDPQSGSQBMPD-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626728; PubChem:CID155007330
|
Local ready
Direct docking supported
|
|
E3L063728
BDB063728
|
BDBM50626729
COc1ccc(S(=O)(=O)N(CC(N)=O)c2cc(CCC(=O)O)c(N(CC(N)=O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C31H32N4O10S2 684.749000 |
LFSYTNSCKJHRHR-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626729; PubChem:CID155007285
|
Local ready
Direct docking supported
|
|
E3L063729
BDB063729
|
BDBM50626730
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(CCC(=O)NC(C)C)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C34H37N3O11S2 727.814000 |
PJEFMHSQDYYADJ-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626730; PubChem:CID154653241
|
Local ready
Direct docking supported
|
|
E3L063730
BDB063730
|
BDBM50626731
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(CCC(=O)N3CCOCC3)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C35H37N3O12S2 755.824000 |
JNAMGNWTFMLHQC-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626731; PubChem:CID154653255
|
Local ready
Direct docking supported
|
|
E3L063731
BDB063731
|
BDBM50626732
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(CCC(N)=O)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C31H31N3O11S2 685.733000 |
PWTZMRSNENLEFH-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626732; PubChem:CID155007319
|
Local ready
Direct docking supported
|
|
E3L063732
BDB063732
|
BDBM50626733
COc1ccc(S(=O)(=O)N(CC(=O)O)c2cc(CCCN(C)Cc3ccccc3)c(N(CC(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1
|
C39H41N3O10S2 775.902000 |
BPXRLRWCXHOGKW-UHFFFAOYSA-N | Q14145 | Kelch-like ECH-associated protein 1 |
BindingDB, PubChem
BindingDB:BDBM50626733; PubChem:CID155007557
|
Local ready
Direct docking supported
|
|
E3L063733
BDB063733
|
2-Benzyl-1,3-diphenylpropane-1,3-dione
O=C(c1ccccc1)C(Cc1ccccc1)C(=O)c1ccccc1
|
C22H18O2 314.384000 |
OBFPJGNSAPBZHO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626734; PubChem:CID12344856
|
Local ready
Direct docking supported
|
|
E3L063734
BDB063734
|
BDBM50626735
O=C(c1ccc(Cl)cc1)C(Cc1ccc(Cl)cc1)C(=O)c1cc(F)ccc1F
|
C22H14Cl2F2O2 419.254000 |
RBCYSMSVSKTDOG-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626735; PubChem:CID172469957
|
Local ready
Direct docking supported
|
|
E3L063735
BDB063735
|
BDBM50626736
O=C(c1ccc(Cl)cc1)C(Cc1cccc(Cl)c1)C(=O)c1cc(F)ccc1F
|
C22H14Cl2F2O2 419.254000 |
MHUITGUNRHOVRJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626736; PubChem:CID172440627
|
Local ready
Direct docking supported
|
|
E3L063736
BDB063736
|
BDBM50626737
O=C(c1ccc(Cl)cc1)C(Cc1ccccc1Cl)C(=O)c1cc(F)ccc1F
|
C22H14Cl2F2O2 419.254000 |
OMGGVWVXEXANPF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626737; PubChem:CID172465054
|
Local ready
Direct docking supported
|
|
E3L063737
BDB063737
|
BDBM50626738
O=C(c1ccc(Cl)cc1)C(Cc1cc(Cl)cc(Cl)c1)C(=O)c1cc(F)ccc1F
|
C22H13Cl3F2O2 453.699000 |
MPXQUHPCLOQQGL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626738; PubChem:CID172459669
|
Local ready
Direct docking supported
|
|
E3L063738
BDB063738
|
BDBM50626739
O=C(c1ccc(Cl)cc1)C(Cc1cccc(F)c1)C(=O)c1cc(F)ccc1F
|
C22H14ClF3O2 402.799000 |
PSJDJNURNAXWOC-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626739; PubChem:CID172451000
|
Local ready
Direct docking supported
|
|
E3L063739
BDB063739
|
BDBM50626740
O=C(c1ccc(Cl)cc1)C(Cc1cccc(C(F)(F)F)c1)C(=O)c1cc(F)ccc1F
|
C23H14ClF5O2 452.806000 |
NZTSHSCBILISGQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626740; PubChem:CID172469615
|
Local ready
Direct docking supported
|
|
E3L063740
BDB063740
|
BDBM50626741
COc1cccc(CC(C(=O)c2ccc(Cl)cc2)C(=O)c2cc(F)ccc2F)c1
|
C23H17ClF2O3 414.835000 |
KYXMMLMMTYHZKI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM50626741; PubChem:CID172451071
|
Local ready
Direct docking supported
|