| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L064921
BDB064921
|
BDBM50642740
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](c2cc(N3CCC(CN4CCC(O[C@H]5C[C@H](Oc6cc(N7C8CCC7CN(c7cc(-c9ccccc9O)nnc7N)C8)ccn6)C5)CC4)CC3)no2)C(C)C)cc1
|
C61H76N12O7S 1121.423000 |
QQVCUSPUMMUFTD-JBVRKRIASA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50642740
|
Local ready
Direct docking supported
|
|
E3L064922
BDB064922
|
BDBM50642743
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](c2cc(OCCN3CCC(O[C@H]4C[C@H](Oc5cc(N6C7CCC6CN(c6cc(-c8ccccc8O)nnc6N)C7)ccn5)C4)CC3)no2)C(C)C)cc1
|
C57H69N11O8S 1068.315000 |
MOMWKZXTQZEWBK-IGIKSVKWSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50642743
|
Local ready
Direct docking supported
|
|
E3L064923
BDB064923
|
BDBM50642744
Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@H](O)CN2C(=O)[C@@H](c2cc(N3CCC(CN4CCC(O[C@H]5C[C@H](Oc6cc(N7C8CCC7CN(c7cc(-c9ccccc9O)nnc7N)C8)ccn6)C5)CC4)CC3)no2)C(C)C)cc1
|
C61H76N12O7S 1121.423000 |
QQVCUSPUMMUFTD-UWKHHCSMSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB
BindingDB:BDBM50642744
|
Local ready
Direct docking supported
|
|
E3L064924
BDB064924
|
BDBM50642745
CN(C)C1=C2C(=O)CCN=C2c2nc3ccccc3c3c2C1N(C1=Nc2c(N(C)C)c4c(c5nc6ccccc6c1c25)NCCC4=O)C3=O
|
C38H30N8O3 646.711000 |
CUTJPTATFAPSLM-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50642745
|
Local ready
Direct docking supported
|
|
E3L064925
BDB064925
|
BDBM50642746
CN(C)c1c2c(c3nc4ccccc4c4c3c1N=C4)NCCC2=O
|
C19H16N4O 316.364000 |
IBUTUOVTDKWFQG-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50642746
|
Local ready
Direct docking supported
|
|
E3L064926
BDB064926
|
BDBM50642747
CC(Sc1nncn1C)c1cccc(NC(=O)c2ccccc2)c1
|
C18H18N4OS 338.436000 |
BTJHNHKMMJBRLF-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642747; PubChem:CID47057284
|
Local ready
Direct docking supported
|
|
E3L064927
BDB064927
|
BDBM50642748
C[C@H](Sc1nncn1C)c1cccc(NC(=O)c2ccccc2)c1
|
C18H18N4OS 338.436000 |
BTJHNHKMMJBRLF-ZDUSSCGKSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642748; PubChem:CID94483278
|
Local ready
Direct docking supported
|
|
E3L064928
BDB064928
|
BDBM50642749
C[C@H](Sc1nncn1C)c1cccc(NC(=O)c2cccc(C(F)(F)F)n2)c1
|
C18H16F3N5OS 407.421000 |
KRMDQIOMACWOQZ-NSHDSACASA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642749; PubChem:CID139360724
|
Local ready
Direct docking supported
|
|
E3L064929
BDB064929
|
BDBM50642750
C[C@H](Sc1nncn1C)c1cccc(NC(=O)c2ccnc(C3CC3)n2)c1
|
C19H20N6OS 380.477000 |
HLTYLYWZQABRHF-LBPRGKRZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642750; PubChem:CID139360895
|
Local ready
Direct docking supported
|
|
E3L064930
BDB064930
|
BDBM50642751
C[C@H](Cc1nncn1C)c1cccc(NC(=O)c2ccnc(C3CC3)n2)c1
|
C20H22N6O 362.437000 |
ZXMXDDSSNLVNRJ-CYBMUJFWSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642751; PubChem:CID139360604
|
Local ready
Direct docking supported
|
|
E3L064931
BDB064931
|
BDBM50642752
Cc1cc(C(=O)Nc2cccc([C@H](C)Cc3nncn3C)c2)nc(C2CC2)n1
|
C21H24N6O 376.464000 |
KZXKWROQQPFRET-CYBMUJFWSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642752; PubChem:CID139360994
|
Local ready
Direct docking supported
|
|
E3L064932
BDB064932
|
BDBM50642753
Cc1cc(C(=O)Nc2cccc(C3(Cc4nocc4C)COC3)c2)nc(C2CC2)n1
|
C23H24N4O3 404.470000 |
HKRBJBLHHFYFBE-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642753; PubChem:CID139350360
|
Local ready
Direct docking supported
|
|
E3L064933
BDB064933
|
Cbl-b-IN-12
Cn1cnnc1CC1(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC6(CC6)C5)cn4c3=O)c2)COC1
|
C28H29F3N6O2 538.574000 |
QWIYHMAATGUUNQ-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642754; PubChem:CID166079710
|
Local ready
Direct docking supported
|
|
E3L064934
BDB064934
|
BDBM50642755
Cn1cnnc1[C@H](c1cccc(-n2cc3c(C(F)(F)F)cc(CN4CCC[C@@](C)(O)C4)cn3c2=O)c1)C1CCC1
|
C29H33F3N6O2 554.617000 |
OXNOMEAWUJEOLG-LBNVMWSVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50642755
|
Local ready
Direct docking supported
|
|
E3L064935
BDB064935
|
BDBM50642756
Cn1cnnc1CC1(c2cc(NC3CCCC3)cc(N3Cc4c(cc(CNC5(C)CCC5)cc4C(F)(F)F)C3=O)c2)CC(F)(F)C1
|
C34H39F5N6O 642.717000 |
MWGBAIIIZZHBCD-UHFFFAOYSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50642756
|
Local ready
Direct docking supported
|
|
E3L064936
BDB064936
|
BDBM50642757
Cn1cnnc1[C@@H](F)C1(c2cccc(N3Cc4c(cc(CN5CC6(C5)CC6(F)F)cc4C(F)(F)F)C3=O)c2)COC1
|
C28H25F6N5O2 577.529000 |
PLTLTIZSFDFQQX-JOCHJYFZSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50642757
|
Local ready
Direct docking supported
|
|
E3L064937
BDB064937
|
BDBM50642758
C[C@H](Cc1nncn1C)c1cccc(NC(=O)N2CCOc3cccnc32)c1
|
C20H22N6O2 378.436000 |
WKQGYDSQKWQBHO-CQSZACIVSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50642758; PubChem:CID155597155
|
Local ready
Direct docking supported
|
|
E3L064938
BDB064938
|
BDBM50642790
CCCCCCCCCCCCCCCC(=O)N[C@@H](C(=O)NCC(=O)N[C@H](CCCCN)C(=O)N[C@H](CO)C(=O)N[C@H](CCCCN)C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](C)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CCCCN)C(N)=O)[C@@H](C)CC)[C@H](C)CC)C(C)C(=O)O
|
C84H139N17O20 1707.135000 |
ROYRTUCMFUGCNJ-HALPZTMQSA-N | P35869 | Aryl hydrocarbon receptor |
BindingDB, PubChem
BindingDB:BDBM50642790; PubChem:CID177382120
|
Local ready
Direct docking supported
|
|
E3L064939
BDB064939
|
BDBM50642832
CN(C)CCn1nnnc1Sc1ccnc2nc(SCc3ccc(Br)cc3)nn12
|
C17H18BrN9S2 492.432000 |
VLCHITJJLDUXRT-UHFFFAOYSA-N | Q96GG9 | DCN1-like protein 1 |
BindingDB, PubChem
BindingDB:BDBM50642832; PubChem:CID177382137
|
Local ready
Direct docking supported
|
|
E3L064940
BDB064940
|
BDBM50642842
Cn1cc(C(F)(F)F)c2cc(-c3cccc([C@]4(c5nncn5C)C[C@@H](C)C4)c3)c(=O)[nH]c21
|
C23H22F3N5O 441.457000 |
QPXAPWFYSQHTAQ-NHPVSCMHSA-N | P22681, Q13191 | E3 ubiquitin-protein ligase CBL-B, E3 ubiquitin-protein ligase CBL |
BindingDB
BindingDB:BDBM50642842
|
Local ready
Direct docking supported
|