| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L064961
BDB064961
|
BDBM50642863
Cc1nnc(Cn2cc(C(F)(F)F)cc(-c3cccc([C@]4(c5nncn5C)C[C@@H](C)C4)c3)c2=O)o1
|
C24H23F3N6O2 484.482000 |
KHBYLZJKYMHXJH-GPCKLQJOSA-N | P22681, Q13191 | E3 ubiquitin-protein ligase CBL-B, E3 ubiquitin-protein ligase CBL |
BindingDB
BindingDB:BDBM50642863
|
Local ready
Direct docking supported
|
|
E3L064962
BDB064962
|
BDBM50642864
C[C@H](c1cnn(C)c1)n1cc(C(F)(F)F)cc(-c2cccc([C@]3(c4nncn4C)C[C@@H](C)C3)c2)c1=O
|
C26H27F3N6O 496.537000 |
QRNMXYQPWPALPI-BFIDETRKSA-N | P22681, Q13191 | E3 ubiquitin-protein ligase CBL, E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50642864
|
Local ready
Direct docking supported
|
|
E3L064963
BDB064963
|
BDBM50642865
C[C@@H](c1cnn(C)c1)n1cc(C(F)(F)F)cc(-c2cccc([C@]3(c4nncn4C)C[C@@H](C)C3)c2)c1=O
|
C26H27F3N6O 496.537000 |
QRNMXYQPWPALPI-XOWTYJCDSA-N | P22681, Q13191 | E3 ubiquitin-protein ligase CBL-B, E3 ubiquitin-protein ligase CBL |
BindingDB
BindingDB:BDBM50642865
|
Local ready
Direct docking supported
|
|
E3L064964
BDB064964
|
PPAR|A/|A agonist 3
CC1(CC/C=N/Nc2nc3ccccc3s2)CCc2cc(OCc3ccc(F)cc3)ccc2O1
|
C27H26FN3O2S 475.589000 |
XZZBEVKWMQCPFH-MUFRIFMGSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM50643353; PubChem:CID170453213
|
Local ready
Direct docking supported
|
|
E3L064965
BDB064965
|
BDBM50643354
CC1(CC/C=N/Nc2ncc(Cl)cc2C(F)(F)F)CCc2cc(OCc3ccc(F)cc3)ccc2O1
|
C26H24ClF4N3O2 521.942000 |
LYLKITZXILLNFB-RVDKCFQWSA-N | P37231, Q07869 | Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM50643354; PubChem:CID177382463
|
Local ready
Direct docking supported
|
|
E3L064966
BDB064966
|
BDBM50643355
C/C(=C\CCC1(C)CCc2cc(OCc3ccc(F)cc3)ccc2O1)CC/C=N/Nc1ncc(Cl)cc1C(F)(F)F
|
C31H32ClF4N3O2 590.061000 |
PIFZJFWIWKNCNB-ISOALGDESA-N | Q07869 | Peroxisome proliferator-activated receptor alpha |
BindingDB, PubChem
BindingDB:BDBM50643355; PubChem:CID170453216
|
Local ready
Direct docking supported
|
|
E3L064967
BDB064967
|
BDBM50643520
Nc1nc2cc(CC[C@H]3C[C@@H](Nc4ncnc5c4C(=O)CCN5)[C@H](O)[C@@H]3O)ccc2cc1Br
|
C23H25BrN6O3 513.396000 |
ZKGZTDISFHHJHP-DFXFOWLGSA-N | O96028, Q9BZ95 | Histone-lysine N-methyltransferase NSD2, Histone-lysine N-methyltransferase NSD3 |
BindingDB, PubChem
BindingDB:BDBM50643520; PubChem:CID177382574
|
Local ready
Direct docking supported
|
|
E3L064968
BDB064968
|
Prmt5-IN-33
Nc1nc2cc(CC[C@H]3C[C@@H](Nc4ncncc4C(=O)c4ccsc4)[C@H](O)[C@@H]3O)ccc2cc1Br
|
C25H24BrN5O3S 554.470000 |
ULTOCOVWRCTJDQ-RLTFZFDCSA-N | O96028, Q9BZ95 | Histone-lysine N-methyltransferase NSD3, Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM50643526; PubChem:CID170836126
|
Local ready
Direct docking supported
|
|
E3L064969
BDB064969
|
BDBM50643720
CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2C2CCN(C(=O)CN3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1
|
C44H46F2N10O6 848.912000 |
ADRVUGPWBAQVJT-UHFFFAOYSA-N | Q09472, Q92793, Q96SW2 | CREB-binding protein, Histone acetyltransferase p300, Protein cereblon |
BindingDB
BindingDB:BDBM50643720
|
Local ready
Direct docking supported
|
|
E3L064970
BDB064970
|
BDBM50643721
CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2C2CCC(CCN3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1
|
C45H49F2N9O5 833.941000 |
UXNPHJKPDROTTJ-UHFFFAOYSA-N | Q09472, Q92793, Q96SW2 | Protein cereblon, Histone acetyltransferase p300, CREB-binding protein |
BindingDB
BindingDB:BDBM50643721
|
Local ready
Direct docking supported
|
|
E3L064971
BDB064971
|
BDBM50643722
CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2[C@H]2CC[C@H](CN3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1
|
C44H47F2N9O5 819.914000 |
NORRDWRSNUOCBV-XCIZWWPASA-N | Q09472, Q92793, Q96SW2 | Protein cereblon, Histone acetyltransferase p300, CREB-binding protein |
BindingDB
BindingDB:BDBM50643722
|
Local ready
Direct docking supported
|
|
E3L064972
BDB064972
|
BDBM50643723
CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2[C@H]2CC[C@@H](CN3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1
|
C44H47F2N9O5 819.914000 |
NORRDWRSNUOCBV-SHXPYSBDSA-N | Q09472, Q92793, Q96SW2 | CREB-binding protein, Protein cereblon, Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM50643723
|
Local ready
Direct docking supported
|
|
E3L064973
BDB064973
|
BDBM50643724
CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2C[C@H]2CC[C@H](CN3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1
|
C45H49F2N9O5 833.941000 |
JHZJBMRRFXYWAC-MEFIJNBOSA-N | Q09472, Q92793, Q96SW2 | CREB-binding protein, Protein cereblon, Histone acetyltransferase p300 |
BindingDB
BindingDB:BDBM50643724
|
Local ready
Direct docking supported
|
|
E3L064974
BDB064974
|
BDBM50643725
CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2CC2CCC(N3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1
|
C44H47F2N9O5 819.914000 |
NYSBJQXVHZZLDQ-UHFFFAOYSA-N | Q09472, Q92793, Q96SW2 | Protein cereblon, Histone acetyltransferase p300, CREB-binding protein |
BindingDB
BindingDB:BDBM50643725
|
Local ready
Direct docking supported
|
|
E3L064975
BDB064975
|
BDBM50643726
CC(=O)N1CCc2c(c(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)nn2C2CCC(N3Cc4cc5c(cc4C3)C(=O)N(C3CCC(=O)NC3=O)C5=O)CC2)C1
|
C43H45F2N9O5 805.887000 |
XMMPMEMOIBXWRN-UHFFFAOYSA-N | Q09472, Q92793, Q96SW2 | CREB-binding protein, Histone acetyltransferase p300, Protein cereblon |
BindingDB
BindingDB:BDBM50643726
|
Local ready
Direct docking supported
|
|
E3L064976
BDB064976
|
BDBM50644206
O=C(CNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O)NCCCCN1CCN(c2ccc(-c3cnc(NCc4ccco4)n4cnnc34)cc2)CC1
|
C39H41N11O6 759.828000 |
XWEAJJXKEDCFNU-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB
BindingDB:BDBM50644206
|
Local ready
Direct docking supported
|
|
E3L064977
BDB064977
|
BDBM50644207
Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCNC(=O)CCCCN2CCN(c3ccc(-c4cnc(NCc5ccco5)n5cnnc45)cc3)CC2)C(C)(C)C)cc1
|
C54H70N12O6S 1015.299000 |
USALWZWDTMQMFR-XXZNOAOZSA-N | O75530 | Polycomb protein EED |
BindingDB
BindingDB:BDBM50644207
|
Local ready
Direct docking supported
|
|
E3L064978
BDB064978
|
BDBM50644529
CCCCN(C)CCN(CC)C(=O)CNCc1cc(C(=O)O)ccn1
|
C18H30N4O3 350.463000 |
ZVDVVBQKFXBYJN-UHFFFAOYSA-N | P29375, P41229 | Lysine-specific demethylase 5C, Lysine-specific demethylase 5A |
BindingDB, PubChem
BindingDB:BDBM50644529; PubChem:CID177383169
|
Local ready
Direct docking supported
|
|
E3L064979
BDB064979
|
myristoyl-Asp-Gly-Tyr(PO3H2)-Met-Pro-OH
CCCCCCCCCCCCCC(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)N[C@@H](CCSC)C(=O)N1CCC[C@H]1C(=O)O
|
C39H62N5O13PS 871.988000 |
MBHBSIOGJJYERC-YDPTYEFTSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM50644668; PubChem:CID177383256
|
Local ready
Direct docking supported
|
|
E3L064980
BDB064980
|
BDBM50644669
Cn1cnnc1[C@]1(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC6(CC6)C5)cn4c3=O)c2)C[C@H](C)C1
|
C29H31F3N6O 536.602000 |
RWFOTIRQBYEIRV-GCSLNTQSSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM50644669
|
Local ready
Direct docking supported
|