| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L065705
LIG000275
|
EK-1-8
C#CCN(C)S(=O)(=O)c1ccc(Cl)c(NC(=O)C=C)c1
|
C13H13ClN2O3S 312.778000 |
DFWRPURDSUZKHQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB6
|
Local ready
Direct docking supported
|
|
E3L065706
LIG000276
|
9b
O=C1CCC(N2Cc3c(cccc3-c3ccc(F)cc3)C2=O)C(=O)N1
|
C19H15FN2O3 338.338000 |
DGFWNJLBAJRPPJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1376
|
Local ready
Direct docking supported
|
|
E3L065707
LIG000277
|
Entry 18
CN1CCN([C@@H]2CCCN(c3cnc(C(N)=O)c(Nc4ccc(C5CN(C6CCN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)C5)cc4)n3)C2)C1=O
|
C41H47N11O6 789.898000 |
DGZUZPOSHUXXIO-UYEDPJPISA-N | - | - |
MolGlueDB
MolGlueDB:MGDB572
|
Local ready
Direct docking supported
|
|
E3L065708
LIG000278
|
dWIZ-2
CCN1CCCC[C@@H]1COc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O
|
C21H27N3O4 385.464000 |
DHFJHVJOMHNTSK-NNJIEVJOSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB483
|
Local ready
Direct docking supported
|
|
E3L065710
LIG000280
|
9b
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCN(C(=O)/C=C/c7ccc(C(F)(F)F)cc7)CC6)c(C(F)(F)F)c5)c4c3c2)cn1
|
C36H27F6N7O3 719.646000 |
DHHLCYNWSZNBOO-YIXHJXPBSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1261
|
Local ready
Direct docking supported
|
|
E3L065711
LIG000281
|
LIG000281
CNC(=O)C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(C)=O)C(C)(C)C)c1ccc(-c2scnc2C)cc1
|
C27H37N5O5S 543.690000 |
DHJHMRSRAVXNPQ-MDAIXWLXSA-N | P40337 | von Hippel-Lindau disease tumor suppressor |
BindingDB, e3_ligand
BindingDB:BDBM50615678; e3_ligand:23
|
Local ready
Direct docking supported
|
|
E3L065712
LIG000282
|
12
O=C1CCC(n2cc(-c3cscc3OCc3ccccc3)nn2)C(=O)N1
|
C18H16N4O3S 368.418000 |
DHJYAECRJZDUBS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1305
|
Local ready
Direct docking supported
|
|
E3L065713
LIG000283
|
cmp47
O=C1CCC(N2C(=O)c3cccc(OCc4ccc(CN5CCN(c6ccc(Cl)cc6Cl)CC5)cc4)c3C2=O)C(=O)N1
|
C31H28Cl2N4O5 607.494000 |
DIFUZJAOBZHDGQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB984
|
Local ready
Direct docking supported
|
|
E3L065714
LIG000284
|
compound 17
COc1c(-c2cn(C3CCC(=O)NC3=O)nn2)csc1C(=O)NC1CCCC1
|
C18H21N5O4S 403.464000 |
DKBHYHIIMQGMOW-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB614
|
Local ready
Direct docking supported
|
|
E3L065715
LIG000285
|
14q
Nc1ccccc1SCC1CCC(=O)NC1=O
|
C12H14N2O2S 250.323000 |
DKCSWOFXOBEDFF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50625135; MolGlueDB:MGDB823
|
Local ready
Direct docking supported
|
|
E3L065716
LIG000286
|
DS57
Cn1cc(-n2cnc3c(NCc4nc5cc(Cl)c(Cl)cc5[nH]4)nc(NCCc4cn[nH]c4)nc32)cn1
|
C22H20Cl2N12 523.392000 |
DKIVKUGXNDYWCX-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1610
|
Local ready
Direct docking supported
|
|
E3L065717
LIG000287
|
15b
O=C1CCC(N2Cc3cc([C@H]4C[C@@]4(COOCC(Cl)(Cl)Cl)c4ccc(Br)cc4)ccc3C2=O)C(=O)N1
|
C25H22BrCl3N2O5 616.723000 |
DKLBYSSOZRYYMK-XARDSYGASA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1160
|
Local ready
Direct docking supported
|
|
E3L065718
LIG000288
|
23
CC(C)(O)c1cc2nn([C@H]3CC[C@H](CN4CCC5(CC4)CC(Nc4cccc6c4C(=O)N(C4CCC(=O)NC4=O)C6=O)C5)CC3)cc2cc1NC(=O)c1cccc(C(F)(F)F)n1
|
C45H49F3N8O6 854.931000 |
DLTLPZXACUDKBE-WKZQYAEKSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50639847; MolGlueDB:MGDB125
|
Local ready
Direct docking supported
|
|
E3L065719
LIG000289
|
LC-04-155
Cc1cc2nc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)ccn2n1
|
C20H17N5O3 375.388000 |
DLUKFEPFIRIULR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB419
|
Local ready
Direct docking supported
|
|
E3L065720
LIG000290
|
LC-02-047-P2
O=C1CC[C@H](N2Cc3cc(-c4cnn5ccc(Cl)nc45)ccc3C2=O)C(=O)N1
|
C19H14ClN5O3 395.806000 |
DMUSJBLCTPEHPQ-AWEZNQCLSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB917
|
Local ready
Direct docking supported
|
|
E3L065721
LIG000291
|
22
CCn1nc(N)c2nc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc(CN3CCCC3)c21
|
C26H29N7O3 487.564000 |
DNDGIEAVKFHOMQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1513
|
Local ready
Direct docking supported
|
|
E3L065722
LIG000292
|
Entry 17
CN1CCN([C@@H]2CCCN(c3cnc(C(N)=O)c(Nc4ccc(C5CCN(C6CN(c7ccc8c(c7)C(=O)N(C7CCC(=O)NC7=O)C8=O)C6)CC5)cc4)n3)C2)C1=O
|
C41H47N11O6 789.898000 |
DNFZZBXTXFSJCR-MOFFZIGISA-N | - | - |
MolGlueDB
MolGlueDB:MGDB569
|
Local ready
Direct docking supported
|
|
E3L065723
LIG000293
|
I10
Cc1ccc(-n2nc(C#N)c(=O)n(Cc3ccc(F)cc3)c2=O)cc1C
|
C19H15FN4O2 350.353000 |
DNHCNCVTDUZLDX-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB238
|
Local ready
Direct docking supported
|
|
E3L065724
LIG000294
|
ZXH-1-120
O=C1CCC(N2Cc3c(NC(=O)CNc4ccnc(-c5ccc(-c6ccccc6)cc5)n4)cccc3C2=O)C(=O)N1
|
C31H26N6O4 546.587000 |
DNLINTODGDTHAC-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1129
|
Local ready
Direct docking supported
|
|
E3L065725
LIG000295
|
2
COc1ccc(CNc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1
|
C21H21N3O4 379.416000 |
DNNLAYKDVNFKRI-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB678
|
Local ready
Direct docking supported
|