| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066316
LIG000886
|
ZXH-1-169
O=C1CCC(N2Cc3c(NC4=NC(N5CCC[C@@H]5CO)NC=C4)cccc3C2=O)C(=O)N1
|
C22H26N6O4 438.488000 |
LPNFGUZRKROHJR-PENBGAGESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1150
|
Local ready
Direct docking supported
|
|
E3L066317
LIG000887
|
iDeg-3
C#Cc1ccc(NC(=O)OC[C@]23CN(S(=O)(=O)c4ccc(C(C)(C)C)cc4)C[C@H]2C[C@H]2C[C@@H]3C2(C)C)cc1
|
C31H38N2O4S 534.722000 |
LPVXGYZMYNYSRZ-GGWKSQAJSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB4
|
Local ready
Direct docking supported
|
|
E3L066318
LIG000888
|
DS19
CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)cc3)nc(N3CCOCC3)nc21
|
C24H27N7O 429.528000 |
LQFDMFLOSFCOEO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB160
|
Local ready
Direct docking supported
|
|
E3L066319
LIG000889
|
10
O=C1CCC(N2Cc3c(ccc4c3OCC3(CCN(Cc5ccccc5)CC3)C4)C2=O)C(=O)N1
|
C27H29N3O4 459.546000 |
LQILLXSRZUHAOR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1461
|
Local ready
Direct docking supported
|
|
E3L066320
LIG000890
|
5
CC(C)(C)[C@H](NC(=O)c1cnn2c1OCCC2)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2ccccc2Cl)cc1
|
C31H36ClN5O5 594.112000 |
LQMRTHDEDCZVQY-QGUKFAFCSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1450
|
Local ready
Direct docking supported
|
|
E3L066321
LIG000891
|
20b
O=C1CCC(CS(=O)(=O)c2ccc(Cl)cc2)C(=O)N1
|
C12H12ClNO4S 301.751000 |
LQWHIMHUNQNNLT-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50625142; MolGlueDB:MGDB930
|
Local ready
Direct docking supported
|
|
E3L066322
LIG000892
|
9h
Cc1ccc(NC(=O)C(C)Cc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1Cl
|
C24H24ClN3O4 453.926000 |
LRDXAOKTQOEMDC-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB333
|
Local ready
Direct docking supported
|
|
E3L066323
LIG000893
|
Golcadomide
O=C1CC[C@H](N2Cc3c(NCc4ccc(CN5CC(N6CCOCC6)C5)cc4F)cccc3C2=O)C(=O)N1
|
C28H32FN5O4 521.593000 |
LRGHUDMBXZXFLJ-VWLOTQADSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB915
|
Local ready
Direct docking supported
|
|
E3L066324
LIG000894
|
12
O=C1CCC(N2C(=O)c3ccc(CNC(=O)Nc4cccc(Cl)c4)cc3C2=O)C(=O)N1
|
C21H17ClN4O5 440.843000 |
LRGPIURPNNEALP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB997
|
Local ready
Direct docking supported
|
|
E3L066325
LIG000895
|
18
N#Cc1cccc(C(=O)Nc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)c1
|
C21H16N4O4 388.383000 |
LRPSTRPEQAKYBN-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB761
|
Local ready
Direct docking supported
|
|
E3L066326
LIG000896
|
37
OCCC1CCCCN1c1cc(NCc2ccc(C3=CCOCC3)cc2)n2ncc(Br)c2n1
|
C25H30BrN5O2 512.452000 |
LSDHDKGSCDHNNX-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB301
|
Local ready
Direct docking supported
|
|
E3L066327
LIG000897
|
7
CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(-c2scnc2C)c2ccccc12)C(C)(C)C
|
C28H34N4O4S 522.671000 |
LSGJQVHXTNKDKV-HFRGRHLUSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB58
|
Local ready
Direct docking supported
|
|
E3L066328
LIG000898
|
14
CCCCCCNc1ccc(OC)c2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C20H25N3O5 387.436000 |
LTBSWUBHSIYHHH-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1282
|
Local ready
Direct docking supported
|
|
E3L066329
LIG000899
|
7
Nc1ccc(Cl)c2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C13H10ClN3O4 307.693000 |
LUDFLPZNMRJXCP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1285
|
Local ready
Direct docking supported
|
|
E3L066330
LIG000900
|
Lib-A-18B
O=C(COc1ccc(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1)N/N=C/c1c(Cl)ccc(C(F)(F)F)c1Cl
|
C29H21Cl2F3N4O5 633.410000 |
LUNLCSTWTPIYJT-RHQFVSDJSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB865
|
Local ready
Direct docking supported
|
|
E3L066331
LIG000901
|
cmp46
O=C1CCC(N2C(=O)c3cccc(OCc4ccc(CN5CCN(c6ccc(F)cc6)CC5)cc4)c3C2=O)C(=O)N1
|
C31H29FN4O5 556.594000 |
LVHBPJYWOSHALG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB986
|
Local ready
Direct docking supported
|
|
E3L066332
LIG000902
|
Lib-B-5D
CN1CCN(c2ncc(/C=N/NC(=O)COc3ccccc3-c3cccc4c3CN(C3CCC(=O)NC3=O)C4=O)s2)CC1
|
C30H31N7O5S 601.689000 |
LVHRVDQMZPLTQX-KPGMTVGESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB580
|
Local ready
Direct docking supported
|
|
E3L066333
LIG000903
|
9h
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCN(C(=O)/C=C/C(=O)c7ccc(C)cc7)CC6)c(C(F)(F)F)c5)c4c3c2)cn1
|
C37H30F3N7O4 693.686000 |
LVRXFVRHJYKVBG-WYMLVPIESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB669
|
Local ready
Direct docking supported
|
|
E3L066334
LIG000904
|
DS47
CC(C)[C@H](Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(CO)cc1
|
C38H47N11O4 721.867000 |
LVVKHGPMCAECNF-CONSDPRKSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1607
|
Local ready
Direct docking supported
|
|
E3L066335
LIG000905
|
66
COc1ccc(CCC(=O)Nc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)cc1
|
C23H23N3O5 421.453000 |
LWFHNBPCMHJPOM-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB677
|
Local ready
Direct docking supported
|