| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066844
LIG001414
|
9o
COc1ccc(-c2ccc3[nH]c(=O)c4nnn(-c5ccc(N6CCN(C(=O)/C=C/C(=O)c7ccc(OC)c(OC)c7)CC6)c(C(F)(F)F)c5)c4c3c2)cn1
|
C38H32F3N7O6 739.711000 |
SLAOOSRSOCGXBT-JLHYYAGUSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB665
|
Local ready
Direct docking supported
|
|
E3L066845
LIG001415
|
11d
COc1cc(N)ccc1C(=O)NC1CCC(=O)NC1=O
|
C13H15N3O4 277.280000 |
SLGDHJMSLPDYEO-UHFFFAOYSA-N | Q16531, Q96SW2 | Protein cereblon, DNA damage-binding protein 1 |
BindingDB, MolGlueDB
BindingDB:BDBM50630599; MolGlueDB:MGDB639
|
Local ready
Direct docking supported
|
|
E3L066846
LIG001416
|
dALK-9
Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCN(CCCC(=O)N2CCN(c3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4=O)CC2)CC1
|
C49H58ClN9O8S 968.578000 |
SLSBKVRIALZLHC-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB278
|
Local ready
Direct docking supported
|
|
E3L066847
LIG001417
|
1H
CCCCNC(=O)c1ccc(-c2cccc3c2CN(C2CCC(=O)NC2=O)C3=O)cc1
|
C24H25N3O4 419.481000 |
SMCWCURXIVNEJC-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB441
|
Local ready
Direct docking supported
|
|
E3L066848
LIG001418
|
7b
O=C1CCC(NC(=O)c2cccc([N+](=O)[O-])c2F)C(=O)N1
|
C12H10FN3O5 295.226000 |
SMNUPLVATFTHLP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB554
|
Local ready
Direct docking supported
|
|
E3L066849
LIG001419
|
14l
O=C1CCC(CSCc2ccccc2)C(=O)N1
|
C13H15NO2S 249.335000 |
SMRFUMNKQVWJJK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50625130; MolGlueDB:MGDB944
|
Local ready
Direct docking supported
|
|
E3L066850
LIG001420
|
30
COc1cc2nc([C@H]3CC[C@H](CN4CC5(CC(CCNc6cccc7c6C(=O)N(C6CCC(=O)NC6=O)C7=O)C5)C4)CC3)oc2cc1NC(=O)c1cccc(C(F)(F)F)n1
|
C43H44F3N7O7 827.861000 |
SMSRIGRAQRHPFR-CCHHBTKDSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB723
|
Local ready
Direct docking supported
|
|
E3L066851
LIG001421
|
17
O=C1CCC(N2C(=O)c3cccc(N4CCCC4)c3C2=O)C(=O)N1
|
C17H17N3O4 327.340000 |
SMWRGIUMPZAOKJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1028
|
Local ready
Direct docking supported
|
|
E3L066852
LIG001422
|
MG-Lin3
COc1ccc(C(=O)/C=C/C(=O)N2CCC(C(=O)N(C)c3cccc(-c4ccc5nnc(C)n5n4)c3)CC2)cc1
|
C30H30N6O4 538.608000 |
SNBSKLJHNAQMKY-WYMLVPIESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB648
|
Local ready
Direct docking supported
|
|
E3L066853
LIG001423
|
21
O=C1CCC(N2C(=O)c3cccc(NC4CCCCC4)c3C2=O)C(=O)N1
|
C19H21N3O4 355.394000 |
SNYYDCFMXULVPX-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1038
|
Local ready
Direct docking supported
|
|
E3L066854
LIG001424
|
5
O=C1CCC(N2Cc3cc(-c4cc(CN5CCCC5)c5cc[nH]c5n4)ccc3C2=O)C(=O)N1
|
C25H25N5O3 443.507000 |
SNZGVVSAMPFNLQ-UHFFFAOYSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB, MolGlueDB
BindingDB:BDBM755856; MolGlueDB:MGDB1496
Related BindingDB:BDBM755905
|
Local ready
Direct docking supported
|
|
E3L066855
LIG001425
|
NRX-252262
COc1cc2c(cc1OC)CN(C(=O)c1c(Sc3c(Cl)cccc3Cl)cc(C(F)(F)F)[nH]c1=O)C2
|
C23H17Cl2F3N2O4S 545.366000 |
SPAYLOCXFWJEBL-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB626
|
Local ready
Direct docking supported
|
|
E3L066856
LIG001426
|
Compound 2
O=C1CCC(N2Cc3cc(-c4nc5ccccn5c4Nc4ccc5c(c4)OCCO5)ccc3C2=O)C(=O)N1
|
C28H23N5O5 509.522000 |
SPILVXJZWWFSPM-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1162
|
Local ready
Direct docking supported
|
|
E3L066857
LIG001427
|
EM12-SO2Im(4-Me)
Cc1cn(S(=O)(=O)c2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cn1
|
C17H16N4O5S 388.405000 |
SPIVDQIYOIXBKQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630772; MolGlueDB:MGDB389
|
Local ready
Direct docking supported
|
|
E3L066858
LIG001428
|
AG4061
Cc1nc2c(C)cccc2cc1C(=O)N/N=C/c1ccccc1
|
C19H17N3O 303.365000 |
SPQXEKYWTIHIRU-UDWIEESQSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB410
|
Local ready
Direct docking supported
|
|
E3L066859
LIG001429
|
6
O=C1CCC(N2Cc3cc(NCc4cccc(Oc5ccccc5)c4)ccc3C2=O)C(=O)N1
|
C26H23N3O4 441.487000 |
SQVKSOFCTXVICM-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1214
|
Local ready
Direct docking supported
|
|
E3L066860
LIG001430
|
70
COc1cc(Oc2ccccc2)ccc1C(=O)Nc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O
|
C27H23N3O6 485.496000 |
SSGXQMNAQRSFRQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB641
|
Local ready
Direct docking supported
|
|
E3L066861
LIG001431
|
L06
O=C1CCC(N2Cc3cc(OCCOCCOCCOCc4ccccc4)ccc3C2=O)C(=O)N1
|
C26H30N2O7 482.533000 |
SSHRMRGHFSJXJT-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1084
|
Local ready
Direct docking supported
|
|
E3L066862
LIG001432
|
68
COc1ccc(Oc2ccc(C(=O)Nc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)cc2)cc1
|
C27H23N3O6 485.496000 |
SSPLTBJVNWLIKS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB694
|
Local ready
Direct docking supported
|
|
E3L066863
LIG001433
|
21
CC(C)c1n[nH]c2c(NCc3ccc(-c4cnccn4)cc3)nc(S)nc12
|
C19H19N7S 377.477000 |
SSSSDMAWWISSGW-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB153
|
Local ready
Direct docking supported
|