| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L066788
LIG001358
|
Z4994098932
Cn1nc(C2CCC(=O)NC2=O)c2cc(N)ccc21
|
C13H14N4O2 258.281000 |
RVLTVWYCEFJWGJ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB582
|
Local ready
Direct docking supported
|
|
E3L066789
LIG001359
|
GBD-7
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@H]1CCCN(C(=O)CCCCCCCNc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3=O)C1
|
C43H45N9O6 783.890000 |
RVOGVKYKIOCSFU-MIXNXMPVSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB838
|
Local ready
Direct docking supported
|
|
E3L066790
LIG001360
|
ARV-825
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)Nc1ccc(OCCOCCOCCOCCNc3cccc4c3C(=O)N(C3CCC(=O)NC3=O)C4=O)cc1)c1nnc(C)n1-2
|
C46H47ClN8O9S 923.449000 |
RWLOGRLTDKDANT-TYIYNAFKSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50512415; MolGlueDB:MGDB255
|
Local ready
Direct docking supported
|
|
E3L066792
LIG001362
|
Lib-D-15O
CN1C(=O)CCC(N2Cc3c(cccc3-c3ccccc3OCC(=O)N/N=C/c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)C2=O)C1=O
|
C37H31N5O7S 689.750000 |
RWPBRNQQKWHTOD-CHSHITCJSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB536
|
Local ready
Direct docking supported
|
|
E3L066793
LIG001363
|
2
NCCCCNc1cc(N2C3CCC2CN(c2cc(-c4ccccc4O)nnc2N)C3)ccn1
|
C25H32N8O 460.586000 |
RWZVSXSDBJCUGO-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1312
|
Local ready
Direct docking supported
|
|
E3L066794
LIG001364
|
LYG-305
O=C1CCC(N2Cc3cc(CNC(=O)c4coc5ccccc5c4=O)ccc3C2=O)C(=O)N1
|
C24H19N3O6 445.431000 |
RXCFJHLJVABHJD-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1339
|
Local ready
Direct docking supported
|
|
E3L066795
LIG001365
|
EM12-FS
O=C1CCC(N2Cc3ccc(OS(=O)(=O)F)cc3C2=O)C(=O)N1
|
C13H11FN2O6S 342.304000 |
RXYXBYLQECASPH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630768; MolGlueDB:MGDB1244
|
Local ready
Direct docking supported
|
|
E3L066796
LIG001366
|
49
O=C1CCC(N2Cc3cc(NC(=O)Cc4cccc5ccccc45)ccc3C2=O)C(=O)N1
|
C25H21N3O4 427.460000 |
RYIPWXZJIZGEKX-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1213
|
Local ready
Direct docking supported
|
|
E3L066797
LIG001367
|
AN7113
COc1ccccc1OCC(=O)Nc1cccc(-c2nc3ccccc3c(=O)o2)c1
|
C23H18N2O5 402.406000 |
RYRZXSNWZHIYQX-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1295
|
Local ready
Direct docking supported
|
|
E3L066798
LIG001368
|
19
CC(C)c1n[nH]c2c(NCc3ccc(-c4cnc[nH]4)cc3)nc(S)nc12
|
C18H19N7S 365.466000 |
RZIMRMUSPRWREZ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB152
|
Local ready
Direct docking supported
|
|
E3L066799
LIG001369
|
NE-003
Nc1cc(F)cc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O
|
C13H10FN3O4 291.238000 |
RZUUDCOJNPMCIR-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB793
|
Local ready
Direct docking supported
|
|
E3L066801
LIG001371
|
5
CCN1CCC2(CC2)[C@@H](Oc2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)C1
|
C22H27N3O4 397.475000 |
SAKPRYFSUZZCOQ-ZVAWYAOSSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB481
|
Local ready
Direct docking supported
|
|
E3L066802
LIG001372
|
ML 1-33
CCCCOC(=O)Oc1ccc(C(=O)N2CCN(C(=O)C[C@@H]3N=C(c4ccc(Cl)cc4)c4c(sc(C)c4C)-n4c(C)nnc43)CC2)cc1
|
C35H37ClN6O5S 689.238000 |
SBMAYRMTDNASET-NDEPHWFRSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB450
|
Local ready
Direct docking supported
|
|
E3L066803
LIG001373
|
LIG001373
CN1CCc2cc3c(cc2C1)C(=O)N(C1CCC(=O)NC1=O)C3=O
|
C17H17N3O4 327.340000 |
SCKTXZXEJSBGHV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, e3_ligand
BindingDB:BDBM50628762; e3_ligand:87
|
Local ready
Direct docking supported
|
|
E3L066804
LIG001374
|
LC-04-102
COc1ccccc1-c1ccccc1CN1CCn2c(-c3ccc4c(c3)CN([C@H]3CCC(=O)NC3=O)C4=O)cnc2C1
|
C33H31N5O4 561.642000 |
SDAJXUGBTPSKIA-MHZLTWQESA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1274
|
Local ready
Direct docking supported
|
|
E3L066805
LIG001375
|
23
CN(C)c1ccc2cc(CNc3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)ccc2c1
|
C26H26N4O3 442.519000 |
SDMHUBJZIMDODP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB511
|
Local ready
Direct docking supported
|
|
E3L066806
LIG001376
|
38
Cc1ccnc(-c2ccc(CNc3cc(N4CCCCC4CCO)nc4c(Br)cnn34)cc2)c1
|
C26H29BrN6O 521.463000 |
SEDURQHMOCNULV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB386
|
Local ready
Direct docking supported
|
|
E3L066807
LIG001377
|
cmp30
O=C1CCC(N2Cc3c(OCc4ccc(CN5CCN(c6ccccn6)CC5)cc4)cccc3C2=O)C(=O)N1
|
C30H31N5O4 525.609000 |
SEEBQQVQQLBJNQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1115
|
Local ready
Direct docking supported
|
|
E3L066808
LIG001378
|
Auxin
O=C(O)Cc1c[nH]c2ccccc12
|
C10H9NO2 175.187000 |
SEOVTRFCIGRIMH-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB28
|
Local ready
Direct docking supported
|
|
E3L066810
LIG001380
|
indisulam
NS(=O)(=O)c1ccc(S(=O)(=O)Nc2cccc3c(Cl)c[nH]c23)cc1
|
C14H12ClN3O4S2 385.854000 |
SETFNECMODOHTO-UHFFFAOYSA-N | Q66K64, Q96SW2 | Protein cereblon |
BindingDB, e3_ligand, MolGlueDB
BindingDB:BDBM10890; e3_ligand:8; MolGlueDB:MGDB849
|
Local ready
Direct docking supported
|