| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L067280
LIG001850
|
29
COc1cc2nc([C@H]3CC[C@H](CN4CC5(CC(CCNc6cccc7c6C(=O)N(C6CCC(=O)NC6=O)C7=O)C5)C4)CC3)n(C)c2cc1NC(=O)c1cccc(C(F)(F)F)n1
|
C44H47F3N8O6 840.904000 |
XWENIHGVDBIAKU-YVDKMHGASA-N | - | - |
MolGlueDB
MolGlueDB:MGDB722
|
Local ready
Direct docking supported
|
|
E3L067281
LIG001851
|
NVP2
COC[C@@H](C)N[C@H]1CC[C@H](Nc2cc(-c3cccc(NCC4(C#N)CCOCC4)n3)c(Cl)cn2)CC1
|
C27H37ClN6O2 513.086000 |
XWQVQSXLXAXOPJ-NJDAHSKKSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1627
Related BindingDB:BDBM50553495
|
Local ready
Direct docking supported
|
|
E3L067282
LIG001852
|
AN5661
Cc1ccc2nc(C)c(C(=O)N/N=C/c3cccc(Cl)c3)cc2c1
|
C19H16ClN3O 337.810000 |
XWRSELVRKJHFDM-SRZZPIQSSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB370
|
Local ready
Direct docking supported
|
|
E3L067283
LIG001853
|
7
O=C1CCC(N2Cc3cc(NC(=O)c4ccc(F)cc4)ccc3C2=O)C(=O)N1
|
C20H16FN3O4 381.363000 |
XXJDKOPXHSTEEV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1058
|
Local ready
Direct docking supported
|
|
E3L067284
LIG001854
|
GBD-4
Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2[C@H]1CCCN(C(=O)CCCCCCNc2cccc3c2C(=O)N(C2CCC(=O)NC2=O)C3=O)C1
|
C42H43N9O6 769.863000 |
XYRZHMWNYMVKNP-BSXJZHEVSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB841
|
Local ready
Direct docking supported
|
|
E3L067285
LIG001855
|
20m
COc1ccc(CS(=O)(=O)CC2CCC(=O)NC2=O)cc1
|
C14H17NO5S 311.359000 |
XZEUGNZMXAQLHL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50625146; MolGlueDB:MGDB679
|
Local ready
Direct docking supported
|
|
E3L067286
LIG001856
|
9j
Cc1c(Cl)cc(NC(=O)CCc2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)cc1N1CCN(C)CC1
|
C28H32ClN5O4 538.048000 |
XZVMOOQGJPDKQV-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB294
|
Local ready
Direct docking supported
|
|
E3L067287
LIG001857
|
LYG-401
O=C1CCC(N2Cc3cc(CNC(=O)C4=Cc5ccccc5OC4)ccc3C2=O)C(=O)N1
|
C24H21N3O5 431.448000 |
YAGPYGRBUFSQGS-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1344
|
Local ready
Direct docking supported
|
|
E3L067288
LIG001858
|
21
CCCCOc1ccc(C2CCC(=O)NC2=O)cc1
|
C15H19NO3 261.321000 |
YAHLYYMAJMLQQH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50630607; MolGlueDB:MGDB452
|
Local ready
Direct docking supported
|
|
E3L067289
LIG001859
|
L5
Cc1ccc(-n2nc(C(=O)N(C)C)c(=O)n(Cc3ccccc3)c2=O)cc1C
|
C21H22N4O3 378.432000 |
YALCOOOIQMKEHD-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB326
|
Local ready
Direct docking supported
|
|
E3L067290
LIG001860
|
LL-K12-13
CCn1cnc2c(NCc3nc4cc(Cl)c(Cl)cc4[nH]3)nc(N3CCN(C(=O)c4ccccc4)CC3)nc21
|
C26H25Cl2N9O 550.454000 |
YBLMOVNFRXJLNG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB467
|
Local ready
Direct docking supported
|
|
E3L067291
LIG001861
|
20d
O=C1CCC(CS(=O)(=O)c2ccc(F)cc2)C(=O)N1
|
C12H12FNO4S 285.296000 |
YCGRFYCBBZDEKG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, MolGlueDB
BindingDB:BDBM50625144; MolGlueDB:MGDB931
|
Local ready
Direct docking supported
|
|
E3L067292
LIG001862
|
ZZ7-16-069
CC(C)S(=O)(=O)c1ccccc1Nc1nc(N[C@@H]2CCCN(C(=O)c3cncnc3)C2)ncc1Cl
|
C23H26ClN7O3S 516.027000 |
YCZFAUJVGDJKSL-QGZVFWFLSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB174
|
Local ready
Direct docking supported
|
|
E3L067293
LIG001863
|
15
Cc1ccccc1C(=O)Nc1ccc2c(c1)CN(C1CCC(=O)NC1=O)C2=O
|
C21H19N3O4 377.400000 |
YDKGAFLLEDYAIB-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB381
|
Local ready
Direct docking supported
|
|
E3L067294
LIG001864
|
ALV1
Cc1ccc(NC(=O)CCc2cccc(NC3=CC(=O)N(C4CCC(=O)NC4=O)C3=O)c2)cc1Cl
|
C25H23ClN4O5 494.935000 |
YDYSAFPHVGVORZ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB338
|
Local ready
Direct docking supported
|
|
E3L067295
LIG001865
|
LC-02-047-P1
O=C1CCC(N2Cc3cc(-c4ccn5ncc(Br)c5n4)ccc3C2=O)C(=O)N1
|
C19H14BrN5O3 440.257000 |
YEFAKXFTUMESCG-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1170
|
Local ready
Direct docking supported
|
|
E3L067296
LIG001866
|
18a
O=C1CCC(N2Cc3cccc([C@@H]4C[C@]4(C(=O)OCC(Cl)(Cl)Cl)c4ccc(Br)cc4)c3C2=O)C(=O)N1
|
C25H20BrCl3N2O5 614.707000 |
YEKKEZIYLYXSAP-UAYVXKRGSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1117
|
Local ready
Direct docking supported
|
|
E3L067297
LIG001867
|
CU-0905
Cn1cc(-n2cnc3c(NCc4nc5ccc(F)c(F)c5[nH]4)nc(N4CCOCC4)nc32)cn1
|
C21H20F2N10O 466.456000 |
YEKKFBQFUXNWHX-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB557
|
Local ready
Direct docking supported
|
|
E3L067298
LIG001868
|
DS48
CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)cc3)nc(NCc3c(Cl)cncc3Cl)nc21
|
C26H24Cl2N8 519.440000 |
YENZFYNZBFLBNQ-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1601
|
Local ready
Direct docking supported
|
|
E3L067299
LIG001869
|
LYG-402
O=C1CCC(N2Cc3cc(CNC(=O)C4=Cc5c(F)cccc5OC4)ccc3C2=O)C(=O)N1
|
C24H20FN3O5 449.438000 |
YEVXVKXAUJXAQP-UHFFFAOYSA-N | - | - |
MolGlueDB
MolGlueDB:MGDB1345
|
Local ready
Direct docking supported
|