| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L006761
BDB006761
|
BDBM152959
COCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C45H55Cl2F2N3O12 938.846000 |
SEWCWTYIVQFEHO-HTLUXGGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152959
|
Local ready
Direct docking supported
|
|
E3L006762
BDB006762
|
BDBM152960
COCCOCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C47H59Cl2F2N3O13 982.899000 |
HHKZLNCUMMYFFW-QNVQBNKXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152960
|
Local ready
Direct docking supported
|
|
E3L006763
BDB006763
|
BDBM152961
COCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C39H43Cl2F2N3O9 806.687000 |
FIUSPLAVQUMADZ-WNCLNVGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152961
|
Local ready
Direct docking supported
|
|
E3L006764
BDB006764
|
BDBM152962
COc1cc(C(=O)OC(C)OC(=O)NCC(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C43H42Cl2F2N4O8 851.731000 |
SERBIEOQNLXPMC-ZTXURCDMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152962
|
Local ready
Direct docking supported
|
|
E3L006765
BDB006765
|
BDBM152963
COc1cc(C(=O)OC(C)OC(=O)NCC(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C36H36Cl2F2N4O8 761.606000 |
MOJSOONVBROIBQ-TWIDIRNWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152963
|
Local ready
Direct docking supported
|
|
E3L006766
BDB006766
|
BDBM152964
COc1cc(C(=O)OC(C)OC(=O)N[C@@H](CCC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C53H52Cl2F2N4O10 1013.919000 |
SFWXFNQCZSIVQB-KSTAIMATSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152964
|
Local ready
Direct docking supported
|
|
E3L006767
BDB006767
|
BDBM152965
COc1cc(C(=O)OCOC(=O)NCC(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C35H34Cl2F2N4O8 747.579000 |
IBPCCKABOONOOP-IDHDNVRGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152965
|
Local ready
Direct docking supported
|
|
E3L006768
BDB006768
|
BDBM152966
COc1cc(C(=O)OCOC(=O)N[C@@H](CCC(=O)OCc2ccccc2)C(=O)OCc2ccccc2)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C52H50Cl2F2N4O10 999.892000 |
BRPCBOVRRRUQGA-RWWNJKSJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152966
|
Local ready
Direct docking supported
|
|
E3L006769
BDB006769
|
BDBM152967
COc1cc(C(=O)OCOC(=O)N[C@@H](CCC(=O)O)C(=O)O)ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@](C#N)(c2ccc(Cl)cc2F)[C@H]1c1cccc(Cl)c1F
|
C38H38Cl2F2N4O10 819.642000 |
XVVVOANZSWBBRN-GJYMCLDQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152967
|
Local ready
Direct docking supported
|
|
E3L006770
BDB006770
|
BDBM152968
COCCOCCOCCOC(=O)OC(OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1)C(C)C
|
C43H51Cl2F2N3O10 878.794000 |
ZAKJWNKNRAVCFJ-OOEPDZAJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152968
|
Local ready
Direct docking supported
|
|
E3L006771
BDB006771
|
BDBM152969
COCCOCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C40H45Cl2F2N3O10 836.713000 |
JJVQHNMPMNBSOH-ABYKZNCSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152969
|
Local ready
Direct docking supported
|
|
E3L006772
BDB006772
|
BDBM152970
COCCOCCOCCOCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C44H53Cl2F2N3O12 924.819000 |
PBGYGAHSAVTEQT-LHSTXJKYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152970
|
Local ready
Direct docking supported
|
|
E3L006773
BDB006773
|
BDBM152971
COCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C38H41Cl2F2N3O9 792.660000 |
ZJHJDFKJNFEVKD-QXVSIQMFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152971
|
Local ready
Direct docking supported
|
|
E3L006774
BDB006774
|
BDBM152972
COCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C39H43Cl2F2N3O9 806.687000 |
FIUSPLAVQUMADZ-WNCLNVGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152972
|
Local ready
Direct docking supported
|
|
E3L006775
BDB006775
|
BDBM152974
COCCOCCOCCOCCOCCOCCOC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C46H57Cl2F2N3O13 968.872000 |
SHYDGEHCVZFEEE-WSLHQQMMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152974
|
Local ready
Direct docking supported
|
|
E3L006776
BDB006776
|
BDBM152975
COCCOCCOCCOCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C51H67Cl2F2N3O15 1071.005000 |
CUROXEMATLEOLG-MXIGFXOKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152975
|
Local ready
Direct docking supported
|
|
E3L006777
BDB006777
|
BDBM152976
COCCOCCOCCOCCOCCOCCOCCOC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C49H63Cl2F2N3O14 1026.952000 |
FWAMGBMTYRUAGD-GWCSZNBCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152976
|
Local ready
Direct docking supported
|
|
E3L006778
BDB006778
|
BDBM152977
COCCOCCNC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C39H44Cl2F2N4O8 805.703000 |
IODHMFRKMBFPPX-WNCLNVGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152977
|
Local ready
Direct docking supported
|
|
E3L006779
BDB006779
|
BDBM152979
COCCOCCNC(=O)OC(C)OC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C39H44Cl2F2N4O8 805.703000 |
IODHMFRKMBFPPX-WNCLNVGJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152979
|
Local ready
Direct docking supported
|
|
E3L006780
BDB006780
|
BDBM152980
COCCOCCNC(=O)OCOC(=O)c1ccc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(c3ccc(Cl)cc3F)[C@H]2c2cccc(Cl)c2F)c(OC)c1
|
C38H42Cl2F2N4O8 791.676000 |
JGHFHBOSDORGTB-QXVSIQMFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM152980
|
Local ready
Direct docking supported
|