| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L008681
BDB008681
|
BDBM212786
COc1ccc(C)nc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C27H27F3N6O3 540.546000 |
VYCQIWRSJCZLRW-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212786; PubChem:CID77847459
|
Local ready
Direct docking supported
|
|
E3L008682
BDB008682
|
BDBM212789
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(S(C)(=O)=O)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H26F3N5O4S 573.597000 |
AJECDHMSVBXLGO-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212789; PubChem:CID77847544
|
Local ready
Direct docking supported
|
|
E3L008683
BDB008683
|
BDBM212791
Cc1cc2ncccc2cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H25F3N6O2 546.553000 |
HGQXRQYMSRQDBS-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212791; PubChem:CID77847545
|
Local ready
Direct docking supported
|
|
E3L008684
BDB008684
|
BDBM212793
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(-c4ccccc4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H27F3N6O2 572.591000 |
GNOVFWLAKMHRNI-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212793; PubChem:CID77847546
|
Local ready
Direct docking supported
|
|
E3L008685
BDB008685
|
BDBM212795
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C(C)(C)O)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H29F3N6O3 554.573000 |
QTMAGMRVTRKHQS-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212795; PubChem:CID77847547
|
Local ready
Direct docking supported
|
|
E3L008686
BDB008686
|
BDBM212797
CC(O)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H27F3N6O3 540.546000 |
ZUZPLVLIJWVBAF-GICMACPYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212797; PubChem:CID77847548
|
Local ready
Direct docking supported
|
|
E3L008687
BDB008687
|
BDBM212799
CCc1ccc(O)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5O3 539.558000 |
IYNWOLBRAUHZSQ-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212799; PubChem:CID136295584
|
Local ready
Direct docking supported
|
|
E3L008688
BDB008688
|
BDBM212801
COCOc1ccc(C(C)C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C31H34F3N5O4 597.638000 |
XHCPQFZTCNWDFJ-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212801; PubChem:CID77847632
|
Local ready
Direct docking supported
|
|
E3L008689
BDB008689
|
BDBM212804
CCc1ccc(OC)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H30F3N5O3 553.585000 |
DKWADIZJDAODDR-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212804; PubChem:CID77847633
|
Local ready
Direct docking supported
|
|
E3L008690
BDB008690
|
BDBM212806
CCOc1ccc(CC)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C30H32F3N5O3 567.612000 |
KSHOKSHHSTUVJT-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212806; PubChem:CID77847634
|
Local ready
Direct docking supported
|
|
E3L008691
BDB008691
|
BDBM212808
CCOc1ccc(C(F)(F)F)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H27F6N5O3 607.555000 |
KSELXUPVQOMYBT-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212808; PubChem:CID77847711
|
Local ready
Direct docking supported
|
|
E3L008692
BDB008692
|
BDBM212810
COc1ccc(C(F)(F)F)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H25F6N5O3 593.528000 |
SIPSTOMUYBQTFD-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212810; PubChem:CID77847712
|
Local ready
Direct docking supported
|
|
E3L008693
BDB008693
|
BDBM212812
CCc1ccc(OCOC)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C30H32F3N5O4 583.611000 |
NMIYTBIGVCLZMN-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212812; PubChem:CID77847713
|
Local ready
Direct docking supported
|
|
E3L008694
BDB008694
|
BDBM212814
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(C(N)=O)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H25F3N6O3 538.530000 |
PZAOOQYWINPUQP-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212814; PubChem:CID77847714
|
Local ready
Direct docking supported
|
|
E3L008695
BDB008695
|
BDBM212816
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C(F)(F)F)ccc3F)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H22F7N5O2 581.492000 |
HXRPHQWCFOPNED-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212816; PubChem:CID77847800
|
Local ready
Direct docking supported
|
|
E3L008696
BDB008696
|
BDBM212818
Cc1ccc(N(C)C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H31F3N6O2 552.601000 |
MENSFCBPGZGQSW-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212818; PubChem:CID77847798
|
Local ready
Direct docking supported
|
|
E3L008697
BDB008697
|
BDBM212820
CCc1ccc(F)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H27F4N5O2 541.549000 |
LCIYWOKEIUACAR-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212820; PubChem:CID77847799
|
Local ready
Direct docking supported
|
|
E3L008698
BDB008698
|
BDBM212821
COc1ccc(C(C)C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C30H32F3N5O3 567.612000 |
ZVKZIXJINSYAMU-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212821; PubChem:CID77847797
|
Local ready
Direct docking supported
|
|
E3L008699
BDB008699
|
BDBM212823
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(N(C)C)ccc3O)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H29F3N6O3 554.573000 |
LWTHIZCVDQWQQB-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212823; PubChem:CID136295598
|
Local ready
Direct docking supported
|
|
E3L008700
BDB008700
|
BDBM212825
CCOc1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C27H27F3N6O3 540.546000 |
ZEIYUEZIAGJZMB-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212825; PubChem:CID77846539
|
Local ready
Direct docking supported
|