| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L008701
BDB008701
|
BDBM212827
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(Cl)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C25H22ClF3N6O2 530.938000 |
LTKBOMQRMUUOEK-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212827; PubChem:CID77846626
|
Local ready
Direct docking supported
|
|
E3L008702
BDB008702
|
BDBM212829
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(OC4CCC4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H29F3N6O3 566.584000 |
NZSRLYHHPHKOSC-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212829; PubChem:CID77846540
|
Local ready
Direct docking supported
|
|
E3L008703
BDB008703
|
BDBM212831
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C(F)F)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H23F5N6O2 546.500000 |
IFBWXBRTVFXFJY-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212831; PubChem:CID77846542
|
Local ready
Direct docking supported
|
|
E3L008704
BDB008704
|
BDBM212833
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(N(C)C)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H28F3N7O2 539.562000 |
WMLYGUKMENOYKL-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212833; PubChem:CID77846541
|
Local ready
Direct docking supported
|
|
E3L008705
BDB008705
|
BDBM212834
Cc1ccn(-c2ccnc(-c3nc4nc(C(=O)O)nc(N[C@H](C)C5CCC5)c4n3Cc3ccc(C(F)(F)F)cc3)c2)n1
|
C29H27F3N8O2 576.583000 |
MJXMZQDFZJFCIO-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212834; PubChem:CID77846543
|
Local ready
Direct docking supported
|
|
E3L008706
BDB008706
|
BDBM212835
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)c(F)c2)c1
|
C28H28F4N6O2 556.564000 |
NXFIGTIERRIJCH-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212835; PubChem:CID77846628
|
Local ready
Direct docking supported
|
|
E3L008707
BDB008707
|
BDBM212836
CC(C)c1ccnc(-c2nc3nc(C(=O)O)nc(N[C@@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H29F3N6O2 538.574000 |
KFBIOFLFOZCHBZ-INIZCTEOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212836; PubChem:CID77846627
|
Local ready
Direct docking supported
|
|
E3L008708
BDB008708
|
BDBM212935
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C4CC4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H27F3N6O2 536.558000 |
MYVJLTOWLXPJPK-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM212935; PubChem:CID77846630
|
Local ready
Direct docking supported
|
|
E3L008709
BDB008709
|
BDBM213102
CC(C)c1ccc(OC(F)(F)F)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C30H29F6N5O3 621.582000 |
MGTLPGNXGJFOQD-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213102; PubChem:CID77846703
|
Local ready
Direct docking supported
|
|
E3L008710
BDB008710
|
BDBM213160
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C(C)(C)C)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H31F3N6O2 552.601000 |
VSLGGEJFUYQULA-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213160; PubChem:CID77846704
|
Local ready
Direct docking supported
|
|
E3L008711
BDB008711
|
BDBM213248
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C4CCC4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H29F3N6O2 550.585000 |
LKMVPAHJPSJAJM-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213248; PubChem:CID77846706
|
Local ready
Direct docking supported
|
|
E3L008712
BDB008712
|
BDBM213251
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C4CCCC4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O2 564.612000 |
FWQJGDGSOHIDSS-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213251; PubChem:CID77846705
|
Local ready
Direct docking supported
|
|
E3L008713
BDB008713
|
BDBM213258
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C4CCCCC4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H33F3N6O2 578.639000 |
KNUDUTGZCATXGF-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213258; PubChem:CID77846784
|
Local ready
Direct docking supported
|
|
E3L008714
BDB008714
|
BDBM213261
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(-c4cccs4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H25F3N6O2S 578.620000 |
JPGSWTKULNKKFB-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213261; PubChem:CID77846785
|
Local ready
Direct docking supported
|
|
E3L008715
BDB008715
|
BDBM213263
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(OC4CCCCC4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H33F3N6O3 594.638000 |
AVSNBUSKCOMANT-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213263; PubChem:CID77846783
|
Local ready
Direct docking supported
|
|
E3L008716
BDB008716
|
BDBM213266
CC(C)Oc1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H29F3N6O3 554.573000 |
KNQKFESJKUCNTI-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213266; PubChem:CID77846629
|
Local ready
Direct docking supported
|
|
E3L008717
BDB008717
|
BDBM213301
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(C(F)(F)F)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H22F6N6O2 564.490000 |
JDLIPAZRZYPFIF-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213301; PubChem:CID77846868
|
Local ready
Direct docking supported
|
|
E3L008718
BDB008718
|
BDBM213305
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc4c3CNC4)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H27F3N6O2 536.558000 |
MHMSSBNDGMNGQN-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213305; PubChem:CID77846786
|
Local ready
Direct docking supported
|
|
E3L008719
BDB008719
|
BDBM213307
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc4ccccc4cn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H25F3N6O2 546.553000 |
FSGNVAPIQLDNEN-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213307; PubChem:CID77846869
|
Local ready
Direct docking supported
|
|
E3L008720
BDB008720
|
BDBM213312
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(-c4ccccc4)n3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H27F3N6O2 572.591000 |
ZXTHMDRJBUUCOY-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213312; PubChem:CID77846870
|
Local ready
Direct docking supported
|