| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L008801
BDB008801
|
BDBM213858
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(OC(F)F)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H24F5N5O3 561.511000 |
TYCRYGFMBPJRJV-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213858; PubChem:CID90324988
|
Local ready
Direct docking supported
|
|
E3L008802
BDB008802
|
BDBM213859
CC(O)c1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1
|
C28H28F3N5O3 539.558000 |
HNGBTXDIFJVZRD-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213859; PubChem:CID90324990
|
Local ready
Direct docking supported
|
|
E3L008803
BDB008803
|
BDBM213860
Cc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1F
|
C27H25F4N5O2 527.522000 |
YNYIXFMMLYCGBP-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213860; PubChem:CID90317577
|
Local ready
Direct docking supported
|
|
E3L008804
BDB008804
|
BDBM213861
Cc1ccc(F)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C27H25F4N5O2 527.522000 |
IKBACQRLTDXNDZ-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213861; PubChem:CID118558537
|
Local ready
Direct docking supported
|
|
E3L008805
BDB008805
|
BDBM213862
COc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1F
|
C27H25F4N5O3 543.521000 |
VHWINEYCSMNADV-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213862; PubChem:CID90317553
|
Local ready
Direct docking supported
|
|
E3L008806
BDB008806
|
BDBM213863
COc1ccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1C
|
C28H28F3N5O3 539.558000 |
CACMBYRFDYTAKW-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213863; PubChem:CID90324913
|
Local ready
Direct docking supported
|
|
E3L008807
BDB008807
|
BDBM213864
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc4nccnc4c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H24F3N7O2 547.541000 |
UORRLNPPAFTPOH-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213864; PubChem:CID90324914
|
Local ready
Direct docking supported
|
|
E3L008808
BDB008808
|
BDBM213865
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cccc(-n4cccc4)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H27F3N6O2 560.580000 |
MOMIHCLLRSQXJQ-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213865; PubChem:CID90318180
|
Local ready
Direct docking supported
|
|
E3L008809
BDB008809
|
BDBM213866
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc4c(ccn4C)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H27F3N6O2 548.569000 |
UJCHABYNNNWUFS-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213866; PubChem:CID90317865
|
Local ready
Direct docking supported
|
|
E3L008810
BDB008810
|
BDBM213867
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(-c4ccccc4)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H28F3N5O2 571.603000 |
YHTQRJKSPVDWAP-LJQANCHMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213867; PubChem:CID90318062
|
Local ready
Direct docking supported
|
|
E3L008811
BDB008811
|
BDBM213868
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(C4CCCCC4)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H34F3N5O2 577.651000 |
VNOMRZBTNWUETH-LJQANCHMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213868; PubChem:CID90325205
|
Local ready
Direct docking supported
|
|
E3L008812
BDB008812
|
BDBM213869
Cc1ccc2cc(-c3nc4nc(C(=O)O)nc(N[C@H](C)C5CCC5)c4n3Cc3ccc(C(F)(F)F)cc3)ccc2n1
|
C30H27F3N6O2 560.580000 |
LIXIHQURQWNETJ-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213869; PubChem:CID90325001
|
Local ready
Direct docking supported
|
|
E3L008813
BDB008813
|
BDBM213870
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(-c4ccccc4)c(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H27F4N5O2 589.593000 |
JODXQQQVZJOIAX-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213870; PubChem:CID118558648
|
Local ready
Direct docking supported
|
|
E3L008814
BDB008814
|
BDBM213871
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(N(C)C)c(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H28F4N6O2 556.564000 |
XQKFFTWPOUGLEQ-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213871; PubChem:CID118566458
|
Local ready
Direct docking supported
|
|
E3L008815
BDB008815
|
BDBM213872
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(C(C)(C)C)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H32F3N5O2 551.613000 |
LGZODTKQKSUUNF-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213872; PubChem:CID90318275
|
Local ready
Direct docking supported
|
|
E3L008816
BDB008816
|
BDBM213873
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(Cl)c(C(F)(F)F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H22ClF6N5O2 597.947000 |
UYMMRTNPASUVDO-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213873; PubChem:CID90317671
|
Local ready
Direct docking supported
|
|
E3L008817
BDB008817
|
BDBM213874
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(C(=O)C4CC4)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H28F3N5O3 563.580000 |
ZPKBUCKXSSWKOK-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213874; PubChem:CID90325002
|
Local ready
Direct docking supported
|
|
E3L008818
BDB008818
|
BDBM213875
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc4occc4c3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H24F3N5O3 535.526000 |
MNJJHDMHCULVTP-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213875; PubChem:CID118558967
|
Local ready
Direct docking supported
|
|
E3L008819
BDB008819
|
BDBM213876
Cc1cc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)ccn1
|
C26H25F3N6O2 510.520000 |
OBPDTBMYEVREOW-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213876; PubChem:CID118566459
|
Local ready
Direct docking supported
|
|
E3L008820
BDB008820
|
BDBM213877
COc1ccc(C)cc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H28F3N5O3 539.558000 |
ALITUHWAULPBKY-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213877; PubChem:CID90318038
|
Local ready
Direct docking supported
|