| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L008781
BDB008781
|
BDBM213838
CCCc1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)c(F)c2)c1
|
C28H28F4N6O2 556.564000 |
YSQZWGFTYNZTKJ-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213838; PubChem:CID77847127
|
Local ready
Direct docking supported
|
|
E3L008782
BDB008782
|
BDBM213839
CC(C)c1cncc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H29F3N6O2 538.574000 |
HZFGGCYEKIGWOR-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213839; PubChem:CID77847206
|
Local ready
Direct docking supported
|
|
E3L008783
BDB008783
|
BDBM213840
Cc1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1F
|
C26H24F4N6O2 528.510000 |
MKVVYYAEHKOIRQ-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213840; PubChem:CID77847207
|
Local ready
Direct docking supported
|
|
E3L008784
BDB008784
|
BDBM213841
CC(C)c1ccc(OC(F)(F)F)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(OC(F)(F)F)c(F)c2)c1
|
C30H28F7N5O4 655.571000 |
BBORVPSOLRJJKI-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213841; PubChem:CID77847208
|
Local ready
Direct docking supported
|
|
E3L008785
BDB008785
|
BDBM213842
Cc1ccc(OC(F)(F)F)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H25F6N5O3 593.528000 |
VMMJZYQTNAVFJG-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213842; PubChem:CID77847289
|
Local ready
Direct docking supported
|
|
E3L008786
BDB008786
|
BDBM213843
CC(C)Cc1ccnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H31F3N6O2 552.601000 |
LDKFZQGGDHLUKR-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213843; PubChem:CID77847290
|
Local ready
Direct docking supported
|
|
E3L008787
BDB008787
|
BDBM213844
Cc1cnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cc1C(C)C
|
C29H31F3N6O2 552.601000 |
QGRACPQJYPBTIE-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213844; PubChem:CID77847209
|
Local ready
Direct docking supported
|
|
E3L008788
BDB008788
|
BDBM213845
Cc1c(C(C)C)ccnc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H31F3N6O2 552.601000 |
NFPWPVBREXKEHT-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213845; PubChem:CID77847210
|
Local ready
Direct docking supported
|
|
E3L008789
BDB008789
|
BDBM213846
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(CCC(C)(C)C)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C31H35F3N6O2 580.655000 |
XJYUSWHPIOERNH-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213846; PubChem:CID77847291
|
Local ready
Direct docking supported
|
|
E3L008790
BDB008790
|
BDBM213847
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3cc(CCC4CC4)ccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O2 564.612000 |
WMBWXACMPVNARQ-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213847; PubChem:CID77847292
|
Local ready
Direct docking supported
|
|
E3L008791
BDB008791
|
BDBM213848
Cc1cnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(OC(F)(F)F)c(F)c2)cc1C(C)C
|
C29H30F4N6O3 586.590000 |
UCYHOZZXPLFIQY-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213848; PubChem:CID90317535
|
Local ready
Direct docking supported
|
|
E3L008792
BDB008792
|
BDBM213849
Cc1c(C(C)C)ccnc1-c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(OC(F)(F)F)c(F)c1
|
C29H30F4N6O3 586.590000 |
AHEVSJWGKXEWQW-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213849; PubChem:CID77847374
|
Local ready
Direct docking supported
|
|
E3L008793
BDB008793
|
BDBM213850
Cc1cnc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)c(F)c2)cc1C(C)C
|
C29H30F4N6O2 570.591000 |
DXTTWABJZFINNX-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213850; PubChem:CID118558877
|
Local ready
Direct docking supported
|
|
E3L008794
BDB008794
|
BDBM213851
Cc1cc(C(C)C)cc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)n1
|
C29H31F3N6O2 552.601000 |
QWKRHUONCKDNKB-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213851; PubChem:CID118558566
|
Local ready
Direct docking supported
|
|
E3L008795
BDB008795
|
BDBM213852
Cc1cc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)n(C)n1
|
C25H26F3N7O2 513.524000 |
UQRCJFHATWZBDG-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213852; PubChem:CID90318463
|
Local ready
Direct docking supported
|
|
E3L008796
BDB008796
|
BDBM213853
Cc1c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)cnn1C
|
C25H26F3N7O2 513.524000 |
KYPQNKAGEBEZAW-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213853; PubChem:CID90317885
|
Local ready
Direct docking supported
|
|
E3L008797
BDB008797
|
BDBM213854
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C26H24F3N5O2 495.505000 |
BXBWWWXFLYQGJY-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213854; PubChem:CID118566456
|
Local ready
Direct docking supported
|
|
E3L008798
BDB008798
|
BDBM213855
C[C@@H](Nc1nc(C(=O)O)nc2nc(-c3ccc(N4CCOCC4)cc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C30H31F3N6O3 580.611000 |
KENJYSUSMPMXQQ-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213855; PubChem:CID118566457
|
Local ready
Direct docking supported
|
|
E3L008799
BDB008799
|
BDBM213856
CC(C)Oc1cccc(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C29H30F3N5O3 553.585000 |
UMMQUNRWTUDVPZ-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213856; PubChem:CID90318438
|
Local ready
Direct docking supported
|
|
E3L008800
BDB008800
|
BDBM213857
Cc1ccc(C)c(-c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2Cc2ccc(C(F)(F)F)cc2)c1
|
C28H28F3N5O2 523.559000 |
LREOJRJQEKWOJZ-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM213857; PubChem:CID90324989
|
Local ready
Direct docking supported
|