| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010301
BDB010301
|
BDBM223046
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C30H40N6O3 532.689000 |
XGVJFXYBZSOQBA-CTVDGRRTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223046
|
Local ready
Direct docking supported
|
|
E3L010302
BDB010302
|
BDBM223200
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCOC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H40N8O3 572.714000 |
BWYQXHSITMJOOM-CTVDGRRTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223200
|
Local ready
Direct docking supported
|
|
E3L010303
BDB010303
|
Kdoam-1
O=C(O)c1ccnc(CN2CCNCC2)c1
|
C11H15N3O2 221.260000 |
VRQYPXABZCTNAE-UHFFFAOYSA-N | P41229 | Lysine-specific demethylase 5C |
BindingDB, PubChem
BindingDB:BDBM223317; PubChem:CID126961671
|
Local ready
Direct docking supported
|
|
E3L010304
BDB010304
|
Kdoam-28
CCNC(=O)c1ccnc(CNCC(=O)N(CC)CCN(C)C)c1
|
C17H29N5O2 335.452000 |
WXFDDWMINUVYFL-UHFFFAOYSA-N | P29375, P41229, Q9BY66 | Lysine-specific demethylase 5A, Lysine-specific demethylase 5C, Lysine-specific demethylase 5D |
BindingDB, PubChem
BindingDB:BDBM223318; PubChem:CID126961672
|
Local ready
Direct docking supported
|
|
E3L010305
BDB010305
|
Kdoam-29
CCN(CCN(C)C)C(=O)CNCc1cc(C(=O)N(C)C)ccn1
|
C17H29N5O2 335.452000 |
VHKSSHRSJGZQOV-UHFFFAOYSA-N | P29375, P41229, Q9BY66 | Lysine-specific demethylase 5D, Lysine-specific demethylase 5C, Lysine-specific demethylase 5A |
BindingDB, PubChem
BindingDB:BDBM223319; PubChem:CID126961673
|
Local ready
Direct docking supported
|
|
E3L010306
BDB010306
|
Kdoam-25
CCN(CCN(C)C)C(=O)CNCc1cc(C(N)=O)ccn1
|
C15H25N5O2 307.398000 |
PNFMVADNCOGWME-UHFFFAOYSA-N | P29375, P41229, Q9BY66 | Lysine-specific demethylase 5A, Lysine-specific demethylase 5C, Lysine-specific demethylase 5D |
BindingDB, PubChem
BindingDB:BDBM223320; PubChem:CID91810435
|
Local ready
Direct docking supported
|
|
E3L010307
BDB010307
|
BDBM223399
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC[C@@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H42N6O2 530.717000 |
KNNKZRXYGBJOGR-NMOFPLQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223399
|
Local ready
Direct docking supported
|
|
E3L010308
BDB010308
|
BDBM223401
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCC[C@@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H42N8O2 570.742000 |
IUMIBSNQDAICDJ-NMOFPLQQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223401
|
Local ready
Direct docking supported
|
|
E3L010309
BDB010309
|
BDBM223402
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H42N6O2 530.717000 |
KNNKZRXYGBJOGR-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223402
|
Local ready
Direct docking supported
|
|
E3L010310
BDB010310
|
BDBM223405
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCC[C@H]3c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H42N8O2 570.742000 |
IUMIBSNQDAICDJ-XAISMOLKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223405
|
Local ready
Direct docking supported
|
|
E3L010311
BDB010311
|
BDBM223590
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3cccc(F)c3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H41FN6O2 548.707000 |
MIHTWQRHPGCHEK-FDBHIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223590
|
Local ready
Direct docking supported
|
|
E3L010312
BDB010312
|
BDBM223591
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCc4ccccc4C3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H38N6O2 502.663000 |
LNNZGVLAPMXBTE-VAMGGRTRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223591
|
Local ready
Direct docking supported
|
|
E3L010313
BDB010313
|
BDBM223592
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3ccc(F)cc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H41FN6O2 548.707000 |
VPBZQLDEBHUVLT-FDBHIMERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223592
|
Local ready
Direct docking supported
|
|
E3L010314
BDB010314
|
BDBM223593
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3cccnc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C30H41N7O2 531.705000 |
ASKWPPBHHPLPMZ-VRKKQRBZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223593
|
Local ready
Direct docking supported
|
|
E3L010315
BDB010315
|
BDBM223594
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCC4CCCCC43)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H44N6O2 508.711000 |
KOJCLWPAGMFLHG-ONSKCLHQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223594
|
Local ready
Direct docking supported
|
|
E3L010316
BDB010316
|
BDBM223595
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3c3ccccn3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C30H41N7O2 531.705000 |
DMLDTQPTYLJEEZ-VRKKQRBZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223595
|
Local ready
Direct docking supported
|
|
E3L010317
BDB010317
|
BDBM223596
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCC4CCCCC4C3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H44N6O2 508.711000 |
SJZGJACTCZCGST-ONSKCLHQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223596
|
Local ready
Direct docking supported
|
|
E3L010318
BDB010318
|
BDBM223598
CC(c1ccccn1)N(C)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H39N9O2 545.692000 |
KFXZEQWAZQTADD-LAURYZNVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223598
|
Local ready
Direct docking supported
|
|
E3L010319
BDB010319
|
BDBM223600
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3C4CCCC3CC4)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H40N6O2 480.657000 |
OSCWMTKQFHWFAJ-GEKRZWMNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223600
|
Local ready
Direct docking supported
|
|
E3L010320
BDB010320
|
BDBM223601
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3C4CCCC3CC4)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C28H40N8O2 520.682000 |
JSQINBDCRIINDH-GEKRZWMNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM223601
|
Local ready
Direct docking supported
|