| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010281
BDB010281
|
BDBM222701
C=CCN(c1nc(C(=O)O)nc2nc(N[C@@H](C)c3cccc(F)c3)n(Cc3ccc(C(F)(F)F)cc3)c12)[C@H](C)C1CCC1
|
C31H32F4N6O2 596.629000 |
GUVPZORGCUFSDC-RBUKOAKNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222701; PubChem:CID90325107
|
Local ready
Direct docking supported
|
|
E3L010282
BDB010282
|
BDBM222702
C[C@@H](Nc1nc(C(=O)O)nc2nc(N(CC3CC3)[C@@H](C)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C32H35F3N6O2 592.666000 |
IOCDCHWUPOWWIT-UXHICEINSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222702; PubChem:CID90317807
|
Local ready
Direct docking supported
|
|
E3L010283
BDB010283
|
BDBM222703
C=CCN(c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)C(C)c1ccccn1
|
C30H32F3N7O2 579.627000 |
SQTCNEKLZLSYNB-MRTLOADZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222703; PubChem:CID90318467
|
Local ready
Direct docking supported
|
|
E3L010284
BDB010284
|
BDBM222704
C=CCN(c1nc(C(=O)O)nc2nc(NC(C)c3ccccn3)n(Cc3ccc(C(F)(F)F)cc3)c12)[C@H](C)C1CCC1
|
C30H32F3N7O2 579.627000 |
HVDPLBZWKVZRPX-MUMRKEEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222704; PubChem:CID90318605
|
Local ready
Direct docking supported
|
|
E3L010285
BDB010285
|
BDBM222705
CCCN(c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)C(C)c1ccccn1
|
C30H34F3N7O2 581.643000 |
KYBCQTLEZZVZAW-MRTLOADZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222705; PubChem:CID90317674
|
Local ready
Direct docking supported
|
|
E3L010286
BDB010286
|
BDBM222706
CC1CCN(C)C(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C1
|
C27H42N6O2 482.673000 |
CJXHLCPTWKUUKT-SKZNFHJNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222706
|
Local ready
Direct docking supported
|
|
E3L010287
BDB010287
|
BDBM222707
CCN1CCC(C)CC1c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H44N6O2 496.700000 |
BADDXNWQCSGWPA-ZXIXHTNESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222707
|
Local ready
Direct docking supported
|
|
E3L010288
BDB010288
|
BDBM222708
CCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)nc1
|
C30H31N7O4 553.623000 |
SYNIXGWDJNBQOP-UHFFFAOYSA-N | P37231 | Regulatory protein GAL4 |
BindingDB, PubChem
BindingDB:BDBM222708; PubChem:CID136173247
|
Local ready
Direct docking supported
|
|
E3L010289
BDB010289
|
BDBM222709
CCCc1nc(C2CC2)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)nc1
|
C30H29N7O4 551.607000 |
KTJROCSEBPVYQG-UHFFFAOYSA-N | P37231 | Regulatory protein GAL4 |
BindingDB, PubChem
BindingDB:BDBM222709; PubChem:CID136173248
|
Local ready
Direct docking supported
|
|
E3L010290
BDB010290
|
BDBM222710
CCCCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)nc1
|
C32H35N7O4 581.677000 |
KKDVUJRGMGHAOG-UHFFFAOYSA-N | P37231 | Regulatory protein GAL4 |
BindingDB, PubChem
BindingDB:BDBM222710; PubChem:CID136173249
|
Local ready
Direct docking supported
|
|
E3L010291
BDB010291
|
BDBM222711
CCCCCc1nc(C2CC2)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2noc(=O)[nH]2)nc1
|
C32H33N7O4 579.661000 |
PNNKISQBGIITSO-UHFFFAOYSA-N | P37231 | Regulatory protein GAL4 |
BindingDB, PubChem
BindingDB:BDBM222711; PubChem:CID136173251
|
Local ready
Direct docking supported
|
|
E3L010292
BDB010292
|
BDBM222715
CC1CCCN(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C1C
|
C27H42N6O2 482.673000 |
MCRQLFJJONWNJH-RFBOWNPMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222715
|
Local ready
Direct docking supported
|
|
E3L010293
BDB010293
|
BDBM222717
CC(C)CC1CCCCN1c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H46N6O2 510.727000 |
FLEHUWSFTUCFDW-VCJJEUFXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222717
|
Local ready
Direct docking supported
|
|
E3L010294
BDB010294
|
BDBM222774
CC(C)CC1CCCCN1c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C30H46N8O2 550.752000 |
NWEIDWAFHNNKSU-VCJJEUFXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222774
|
Local ready
Direct docking supported
|
|
E3L010295
BDB010295
|
BDBM222776
C[C@@H](Nc1nc(C(=O)O)nc2nc(N3CCCCC3C3CCCCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C31H48N6O2 536.765000 |
HRBNLVRCIOFETR-AEGADVIYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222776
|
Local ready
Direct docking supported
|
|
E3L010296
BDB010296
|
BDBM222838
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCCCC3C3CCCCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C32H48N8O2 576.790000 |
KODPHPWWEUEVMZ-AEGADVIYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222838
|
Local ready
Direct docking supported
|
|
E3L010297
BDB010297
|
BDBM222841
CC1CCCN(c2nc3nc(C(=O)O)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C1c1ccccc1
|
C32H44N6O2 544.744000 |
RGEKKEWXGMWQNT-XEEGGGNASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222841
|
Local ready
Direct docking supported
|
|
E3L010298
BDB010298
|
BDBM222844
CC1CCCN(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)C1c1ccccc1
|
C33H44N8O2 584.769000 |
IHTRIKSPZZHEJB-XEEGGGNASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222844
|
Local ready
Direct docking supported
|
|
E3L010299
BDB010299
|
BDBM222845
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(N3CCC[C@H]3CF)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H37FN8O2 512.634000 |
UKMLKEJYPDRXEY-MTNOOBJLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222845
|
Local ready
Direct docking supported
|
|
E3L010300
BDB010300
|
BDBM222847
C[C@H]1CC[C@H](Cn2c(N3CCOC[C@H]3c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(N4CC[C@@H]4C4CCC4)c32)CC1
|
C32H40N8O3 584.725000 |
UIIOKPOSKGKKIE-YENTXNKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM222847
|
Local ready
Direct docking supported
|