| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010241
BDB010241
|
BDBM221965
C[C@@H](Nc1nc(C(=O)O)nc2nc(COCc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H28F3N5O3 539.558000 |
WBECRWSWISZHNI-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221965; PubChem:CID90325505
|
Local ready
Direct docking supported
|
|
E3L010242
BDB010242
|
BDBM221966
CC(C)CC(=O)N(C)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C26H31F3N6O3 532.567000 |
SLUNUCQUBDJTEK-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221966; PubChem:CID90320083
|
Local ready
Direct docking supported
|
|
E3L010243
BDB010243
|
BDBM221968
C[C@@H](Nc1nc(C(=O)O)nc2nc(N(C)C(=O)C3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H33F3N6O3 558.605000 |
NCCKFRAMKWGWHR-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221968; PubChem:CID90320039
|
Local ready
Direct docking supported
|
|
E3L010244
BDB010244
|
BDBM221971
CC(C)COC(C)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C26H32F3N5O3 519.568000 |
CGUQCGMKYDLIMB-AAFJCEBUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221971; PubChem:CID90319432
|
Local ready
Direct docking supported
|
|
E3L010245
BDB010245
|
BDBM221972
CC(OCc1ccccc1)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C29H30F3N5O3 553.585000 |
SAPFUJFGGBEILQ-QNSVNVJESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221972; PubChem:CID90317742
|
Local ready
Direct docking supported
|
|
E3L010246
BDB010246
|
BDBM221973
CC(O)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C22H24F3N5O3 463.460000 |
UGKHNXREGYLOCM-JHJMLUEUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221973; PubChem:CID90318015
|
Local ready
Direct docking supported
|
|
E3L010247
BDB010247
|
BDBM221975
CC(Oc1ccccc1)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C28H28F3N5O3 539.558000 |
CGQLGNZYOZCOAG-TZHYSIJRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221975; PubChem:CID90318290
|
Local ready
Direct docking supported
|
|
E3L010248
BDB010248
|
BDBM221976
CC(C)CN(C)C(C)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C27H35F3N6O2 532.611000 |
ZDATYUFGNHUFBY-TZHYSIJRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221976; PubChem:CID90317579
|
Local ready
Direct docking supported
|
|
E3L010249
BDB010249
|
BDBM221977
CC(c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)N(C)c1ccccc1
|
C29H31F3N6O2 552.601000 |
HCEYVZXHOKMBKM-QNSVNVJESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM221977; PubChem:CID90318086
|
Local ready
Direct docking supported
|
|
E3L010250
BDB010250
|
BDBM222372
CC(c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)N(C)C1CCCCC1
|
C29H37F3N6O2 558.649000 |
CBZYGMNGQJBIED-QNSVNVJESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222372; PubChem:CID90318662
|
Local ready
Direct docking supported
|
|
E3L010251
BDB010251
|
BDBM222377
CC(c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1)N(C)Cc1ccccc1
|
C30H33F3N6O2 566.628000 |
FWRRGJPOYFFEOU-MRTLOADZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222377; PubChem:CID90317939
|
Local ready
Direct docking supported
|
|
E3L010252
BDB010252
|
BDBM222382
C[C@@H](Nc1nc(C(=O)O)nc2nc(CN(C)Cc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H31F3N6O2 552.601000 |
DHWHZGNQINTVRQ-GOSISDBHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222382; PubChem:CID90317622
|
Local ready
Direct docking supported
|
|
E3L010253
BDB010253
|
BDBM222395
C[C@@H](Nc1nc(C(=O)O)nc2nc(CN(C)C3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H35F3N6O2 544.622000 |
HEBXCWLQEPJYSG-QGZVFWFLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222395; PubChem:CID90317826
|
Local ready
Direct docking supported
|
|
E3L010254
BDB010254
|
BDBM222674
CCCCc1nc(C(C)C)n(-c2ncc(OCC)cn2)c(=O)c1Cc1ccc(-c2ccccc2-c2nnn[nH]2)nc1
|
C30H33N9O2 551.655000 |
RYHZXBYVUVJCGO-UHFFFAOYSA-N | P37231 | Regulatory protein GAL4 |
BindingDB, PubChem
BindingDB:BDBM222674; PubChem:CID51348175
|
Local ready
Direct docking supported
|
|
E3L010255
BDB010255
|
BDBM222675
C[C@@H](Nc1nc(C(=O)O)nc2nc(C(=O)N[C@@H](CO)c3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C29H29F3N6O4 582.583000 |
QBJOSXCXEQZZSB-IERDGZPVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222675; PubChem:CID90317958
|
Local ready
Direct docking supported
|
|
E3L010256
BDB010256
|
BDBM222676
CC(C)CNC(=O)c1nc2nc(C(=O)O)nc(N[C@H](C)C3CCC3)c2n1Cc1ccc(C(F)(F)F)cc1
|
C25H29F3N6O3 518.540000 |
VCPNDJCZLIZHQK-CQSZACIVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222676; PubChem:CID90325026
|
Local ready
Direct docking supported
|
|
E3L010257
BDB010257
|
BDBM222677
C[C@@H](Nc1nc(C(=O)O)nc2nc(C(=O)NCC3CC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C25H27F3N6O3 516.524000 |
AJWGEIMYQICPIB-CYBMUJFWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222677; PubChem:CID90325040
|
Local ready
Direct docking supported
|
|
E3L010258
BDB010258
|
BDBM222678
C[C@@H](Nc1nc(C(=O)O)nc2nc(C(=O)NCc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C28H27F3N6O3 552.557000 |
NNCHASOLRRWZCH-MRXNPFEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222678; PubChem:CID90318556
|
Local ready
Direct docking supported
|
|
E3L010259
BDB010259
|
BDBM222679
C[C@@H](Nc1nc(C(=O)O)nc2nc(C(=O)NC3CCCCC3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H31F3N6O3 544.578000 |
ZHKHLQKJUMCOTO-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222679; PubChem:CID90325112
|
Local ready
Direct docking supported
|
|
E3L010260
BDB010260
|
BDBM222680
C[C@@H](Nc1nc(C(=O)O)nc2nc(C(=O)Nc3ccccc3)n(Cc3ccc(C(F)(F)F)cc3)c12)C1CCC1
|
C27H25F3N6O3 538.530000 |
PPONAYSMJBFTII-OAHLLOKOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM222680; PubChem:CID90325113
|
Local ready
Direct docking supported
|