| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010841
BDB010841
|
BDBM224757
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3CCCCC3O)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H39N7O3 509.655000 |
MISFBTPLMQGIJL-PQLJQCGPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224757
|
Local ready
Direct docking supported
|
|
E3L010842
BDB010842
|
BDBM224760
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(c4cccc(F)c4)CC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C30H36FN7O2 545.663000 |
OEWOOVSDAOLYPR-GUDVDZBRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224760
|
Local ready
Direct docking supported
|
|
E3L010843
BDB010843
|
BDBM224761
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(C)(O)c3cscn3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H34N8O3S 538.678000 |
PNEHWVATSWGZCX-YHPZBCERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224761
|
Local ready
Direct docking supported
|
|
E3L010844
BDB010844
|
BDBM224764
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(c4ccncc4)CC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H36N8O2 528.661000 |
VASFAFPHXOQDLX-GUDVDZBRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224764
|
Local ready
Direct docking supported
|
|
E3L010845
BDB010845
|
BDBM224765
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(c4cscn4)CC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H34N8O2S 534.690000 |
NTFVJDVNAGNOLV-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224765
|
Local ready
Direct docking supported
|
|
E3L010846
BDB010846
|
BDBM224766
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(C)(O)c3cn(C)cn3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H37N9O3 535.653000 |
RHCNWGSRRHAHCL-QYGAUDADSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224766
|
Local ready
Direct docking supported
|
|
E3L010847
BDB010847
|
BDBM224767
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(C)(O)c3nccs3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H34N8O3S 538.678000 |
HERTWRMHSKZFJU-YHPZBCERSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224767
|
Local ready
Direct docking supported
|
|
E3L010848
BDB010848
|
BDBM224768
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(O)C3CCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H37N7O3 495.628000 |
YBEQPWZBZOSMOA-GLOJTFSJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224768
|
Local ready
Direct docking supported
|
|
E3L010849
BDB010849
|
BDBM224770
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(c4nccs4)CC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C27H34N8O2S 534.690000 |
CAIVHBYICLQWGY-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224770
|
Local ready
Direct docking supported
|
|
E3L010850
BDB010850
|
BDBM224846
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(O)(CO)c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H37N7O4 547.660000 |
SFWPUYVZGIWJKF-AGSQVQQYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224846
|
Local ready
Direct docking supported
|
|
E3L010851
BDB010851
|
BDBM224851
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(C)(F)c3ccccc3F)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H35F2N7O2 551.642000 |
XCADISPPPMQTDK-VOMCSHPCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224851
|
Local ready
Direct docking supported
|
|
E3L010852
BDB010852
|
BDBM224856
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(c4cnn(C)c4)CC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C28H37N9O2 531.665000 |
OXYCTWKWXOADGM-KZNAEPCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224856
|
Local ready
Direct docking supported
|
|
E3L010853
BDB010853
|
BDBM224884
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(O)CCOCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C26H37N7O4 511.627000 |
CVBWVSVCVWGPNV-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224884
|
Local ready
Direct docking supported
|
|
E3L010854
BDB010854
|
BDBM224888
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(F)c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C28H34FN7O2 519.625000 |
BUPHVYHRNNVQJQ-WYKVRPKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224888
|
Local ready
Direct docking supported
|
|
E3L010855
BDB010855
|
BDBM224901
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(O)CCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C25H35N7O3 481.601000 |
MAHPCLNEUZLGSB-BZUAXINKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224901
|
Local ready
Direct docking supported
|
|
E3L010856
BDB010856
|
BDBM224910
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(F)CCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C25H34FN7O2 483.592000 |
AKEYHBCMROZMFU-BZUAXINKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224910
|
Local ready
Direct docking supported
|
|
E3L010857
BDB010857
|
BDBM224926
COC1(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)CCC1
|
C26H37N7O3 495.628000 |
JKLVFSHKQYLOGE-BRWVUGGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224926
|
Local ready
Direct docking supported
|
|
E3L010858
BDB010858
|
BDBM224986
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3CCC3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C25H35N7O2 465.602000 |
UZYDRNXKEUKDQJ-BZUAXINKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM224986
|
Local ready
Direct docking supported
|
|
E3L010859
BDB010859
|
BDBM225026
CC(c1ccccn1)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H36N8O2 516.650000 |
PPWJJTQTFXUAKH-CEBOQPEMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225026
|
Local ready
Direct docking supported
|
|
E3L010860
BDB010860
|
Eed226
CS(=O)(=O)c1ccc(-c2cnc(NCc3ccco3)n3cnnc23)cc1
|
C17H15N5O3S 369.406000 |
DYIRSNMPIZZNBK-UHFFFAOYSA-N | O14965, O75530, O96028, P51617, P61964, Q03164, Q09028, Q15291, Q96L73, Q9BQA1, Q9BZ95 | Histone-lysine N-methyltransferase NSD3, Polycomb protein EED, Interleukin-1 receptor-associated kinase 1, Protein arginine N-methyltransferase 5, Histone-lysine N-methyltransferase EZH2, WD repeat-containing protein 5, Histone-lysine N-methyltransferase NSD2, Histone-lysine N-methyltransferase, H3 lysine-36 specific, Aurora kinase A |
BindingDB, PubChem
BindingDB:BDBM225230; PubChem:CID123132228
|
Local ready
Direct docking supported
|