| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010861
BDB010861
|
BDBM225902
Cc1nc(C2(c3nc4nc(-c5noc(=O)[nH]5)nc(N[C@H](C)C5CCC5)c4n3C[C@H]3CC[C@H](C)CC3)CC2)c(C)s1
|
C29H38N8O2S 562.744000 |
FLTZBIKWNTZPOP-GPMSIDNRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225902
|
Local ready
Direct docking supported
|
|
E3L010862
BDB010862
|
BDBM225903
Cc1nc(C(C)(F)c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)c(C)s1
|
C28H37FN8O2S 568.723000 |
IDLCDIGLTRBYIP-QDRJWFLJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225903
|
Local ready
Direct docking supported
|
|
E3L010863
BDB010863
|
BDBM225904
COC(c1cscn1)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C26H34N8O3S 538.678000 |
IMZYJELFOIFRDR-GLOJTFSJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225904
|
Local ready
Direct docking supported
|
|
E3L010864
BDB010864
|
BDBM225906
CCOC1(c2nc3nc(-c4noc(=O)[nH]4)nc(N[C@H](C)C4CCC4)c3n2C[C@H]2CC[C@H](C)CC2)CCC1
|
C27H39N7O3 509.655000 |
DPYXTDHVOFVKQK-KZNAEPCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225906
|
Local ready
Direct docking supported
|
|
E3L010865
BDB010865
|
BDBM225907
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(C)(F)c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H36FN7O2 533.652000 |
WGZJTJYJBFKWMK-AGSQVQQYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225907
|
Local ready
Direct docking supported
|
|
E3L010866
BDB010866
|
BDBM225909
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C(F)(F)c3ccccc3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C28H33F2N7O2 537.615000 |
ZSWPWGLRISMASB-KZNAEPCWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225909
|
Local ready
Direct docking supported
|
|
E3L010867
BDB010867
|
BDBM225910
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3OCc4ccccc43)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C29H35N7O3 529.645000 |
GBDHRFKBPMOWDI-RUFVAUJOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225910
|
Local ready
Direct docking supported
|
|
E3L010868
BDB010868
|
BDBM225911
C[C@@H](Nc1nc(-c2noc(=O)[nH]2)nc2nc(C3(c4ccccc4)CCO3)n(C[C@H]3CC[C@H](C)CC3)c12)C1CCC1
|
C30H37N7O3 543.672000 |
ZBNZQBQTOMFART-XNBUGRKWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225911
|
Local ready
Direct docking supported
|
|
E3L010869
BDB010869
|
BDBM225912
CCC(CO)c1nc2nc(-c3noc(=O)[nH]3)nc(N[C@H](C)C3CCC3)c2n1C[C@H]1CC[C@H](C)CC1
|
C25H37N7O3 483.617000 |
JBUNCVGLQWIMST-HJNZIYBASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM225912
|
Local ready
Direct docking supported
|
|
E3L010870
BDB010870
|
BDBM226308
C[C@H]1Cc2c([nH]c3ccccc23)[C@H](c2ccc(N3CCC(CN4CCN5c6cc7c(cc6OC[C@H]5C4)C(=O)N([C@@H]4CCC(=O)NC4=O)C7)CC3)cn2)N1CC(F)(F)F
|
C43H47F3N8O4 796.895000 |
SVVDXJZOIJVQTJ-JVSZGHPLSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM226308
|
Local ready
Direct docking supported
|
|
E3L010871
BDB010871
|
BDBM226309
C[C@@H]1Cc2c([nH]c3ccccc23)[C@H](c2cnc(N3CCC4(CC3)C[C@@H](CN3CCN5c6ccc(C(=O)N[C@H]7CCC(=O)NC7=O)nc6OC[C@H]5C3)CO4)nc2)N1CC(F)F
|
C43H50F2N10O5 824.934000 |
YNHWAMPKCMEBHW-BZUDFLMQSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM226309
|
Local ready
Direct docking supported
|
|
E3L010872
BDB010872
|
BDBM226310
C[C@H]1Cc2c([nH]c3ccccc23)[C@H](c2cnc(N3CCC4(CC3)C[C@@H](CN3CCC(c5ccc(N[C@@H]6CCC(=O)NC6=O)cc5)CC3)CO4)nc2)N1CC(F)F
|
C43H52F2N8O3 766.938000 |
RZFDGDVHVIXWFC-QSBUUFQLSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM226310
|
Local ready
Direct docking supported
|
|
E3L010873
BDB010873
|
BDBM226311
C[C@H]1Cc2c([nH]c3ccccc23)[C@H](c2cnc(N3CCC4(CC3)C[C@H](CN3CCC(c5ccc(N[C@H]6CCC(=O)NC6=O)cc5)CC3)CO4)nc2)N1CC(F)F
|
C43H52F2N8O3 766.938000 |
RZFDGDVHVIXWFC-OYERUZJPSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM226311
|
Local ready
Direct docking supported
|
|
E3L010874
BDB010874
|
BDBM226312
C[C@H]1Cc2c([nH]c3ccccc23)[C@H](c2cnc(N3CCC4(CC3)C[C@@H](CN3CCN5c6cc7c(cc6OC[C@@H]5C3)C(=O)N([C@@H]3CCC(=O)NC3=O)C7)CO4)nc2)N1CC(F)F
|
C45H51F2N9O5 835.957000 |
ZUJQZWBFRDDBCA-NWDYBLRLSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM226312
|
Local ready
Direct docking supported
|
|
E3L010875
BDB010875
|
BDBM226313
C[C@H]1CC[C@H](Cn2c(C(O)C3CCOCC3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cccc(Cl)c4)c32)CC1
|
C27H31ClN6O4 539.036000 |
BSSWWWFJLISFPV-STFKQGPRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226313
|
Local ready
Direct docking supported
|
|
E3L010876
BDB010876
|
BDBM226314
C[C@H]1Cc2c([nH]c3ccccc23)[C@H](c2cnc(N3CCC4(CC3)C[C@H](CN3CCN5c6cc7c(cc6OC[C@@H]5C3)C(=O)N([C@@H]3CCC(=O)NC3=O)C7)CO4)nc2)N1CC(F)F
|
C45H51F2N9O5 835.957000 |
ZUJQZWBFRDDBCA-CMHVGWTHSA-N | Q16531, Q96SW2 | DNA damage-binding protein 1 |
BindingDB
BindingDB:BDBM226314
|
Local ready
Direct docking supported
|
|
E3L010877
BDB010877
|
BDBM226395
C[C@H]1CC[C@H](Cn2c(C(O)C3CCOCC3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C27H31ClN6O4 539.036000 |
MJLDCAZXTPWVHI-STFKQGPRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226395
|
Local ready
Direct docking supported
|
|
E3L010878
BDB010878
|
BDBM226396
C[C@H]1CC[C@H](Cn2c(C(=O)C3CCOCC3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C27H29ClN6O4 537.020000 |
NKUMVBSEMXSBQX-WKILWMFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226396
|
Local ready
Direct docking supported
|
|
E3L010879
BDB010879
|
BDBM226397
CC(O)(c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)C1CCOCC1
|
C28H33ClN6O4 553.063000 |
NOMWQZOYBPOBOJ-KEQYIYAOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226397
|
Local ready
Direct docking supported
|
|
E3L010880
BDB010880
|
BDBM226398
C[C@H]1CC[C@H](Cn2c(C(O)C3CCCCC3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C28H33ClN6O3 537.064000 |
FKJCDPDNMNNCIX-XEDXNJDHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226398
|
Local ready
Direct docking supported
|