| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L010901
BDB010901
|
BDBM226422
C[C@H]1CC[C@H](Cn2c(C3(F)COC3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C23H23ClFN7O3 499.934000 |
NCVZTUMDPAGFEC-JOCQHMNTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226422
|
Local ready
Direct docking supported
|
|
E3L010902
BDB010902
|
BDBM226423
C[C@H]1CC[C@H](Cn2c(C(F)C3CCCCC3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C28H32ClFN6O2 539.055000 |
RUFPCPYVLPNVAK-UYJZDEDHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226423
|
Local ready
Direct docking supported
|
|
E3L010903
BDB010903
|
BDBM226424
CC(F)(c1ccccn1)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H27ClFN7O2 548.022000 |
SROALZAYVSHUMV-KEQYIYAOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226424
|
Local ready
Direct docking supported
|
|
E3L010904
BDB010904
|
BDBM226426
CC(F)(c1ccccc1F)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H26ClF2N7O2 566.012000 |
ZJQADQCHJPXNEO-SWGGNHTLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226426
|
Local ready
Direct docking supported
|
|
E3L010905
BDB010905
|
BDBM226428
CC(F)(c1ccccc1F)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H26ClF2N7O2 566.012000 |
DDDSJBFSCZLJQC-SWGGNHTLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226428
|
Local ready
Direct docking supported
|
|
E3L010906
BDB010906
|
BDBM226430
CC(F)(c1ccccn1)c1nc2nc(-c3n[nH]c(=O)o3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H27ClFN7O2 548.022000 |
BTPRNPIEGHXNTM-KEQYIYAOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226430
|
Local ready
Direct docking supported
|
|
E3L010907
BDB010907
|
BDBM226432
C[C@H]1CC[C@H](Cn2c(C3(F)CCC3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C24H25ClFN7O2 497.962000 |
HJNNGBYNHBMVFT-HDJSIYSDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226432
|
Local ready
Direct docking supported
|
|
E3L010908
BDB010908
|
BDBM226433
C[C@H]1CC[C@H](Cn2c(C3(F)CCCCC3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1
|
C26H29ClFN7O2 526.016000 |
GZYHSJNVKGGMKT-WKILWMFISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226433
|
Local ready
Direct docking supported
|
|
E3L010909
BDB010909
|
BDBM226434
C[C@H]1CC[C@H](Cn2c(C3(F)CCCC3)nc3nc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1
|
C25H27ClFN7O2 511.989000 |
LIJYMRRFJKEJLG-SHTZXODSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226434
|
Local ready
Direct docking supported
|
|
E3L010910
BDB010910
|
BDBM226435
C[C@H]1CC[C@H](Cn2c(C(O)c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C28H27ClN6O3 531.016000 |
FDCSXIOLFAFZCA-XEDXNJDHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226435
|
Local ready
Direct docking supported
|
|
E3L010911
BDB010911
|
BDBM226437
C[C@H]1CC[C@H](Cn2c(C(=O)c3ccccc3)nc3nc(-c4noc(=O)[nH]4)nc(-c4cccc(Cl)c4)c32)CC1
|
C28H25ClN6O3 529.000000 |
UBYPAHMRZDLSGE-QAQDUYKDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226437
|
Local ready
Direct docking supported
|
|
E3L010912
BDB010912
|
BDBM226438
COC(c1ccccc1)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C29H29ClN6O3 545.043000 |
GSXREXVDNHAQJP-NUJJYFHVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226438
|
Local ready
Direct docking supported
|
|
E3L010913
BDB010913
|
BDBM226439
COC(c1ccccn1)c1nc2nc(-c3noc(=O)[nH]3)nc(-c3cccc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1
|
C28H28ClN7O3 546.031000 |
AKFYTDTYXBJQQA-XEDXNJDHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM226439
|
Local ready
Direct docking supported
|
|
E3L010914
BDB010914
|
US20260008770, Example 1
CC1CC(c2cccc(N3CCc4c(cc(CN5CC[C@H](F)C5)cc4C(F)(F)F)C3=O)c2)(c2nncn2C)C1
|
C29H31F4N5O 541.593000 |
TTWIHSOCJMMFFD-FKUMYKMDSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM226947; PubChem:CID176004041
|
Local ready
Direct docking supported
|
|
E3L010915
BDB010915
|
BDBM226980
C[C@H]1CCCN(Cc2cc3c(c(C(F)(F)F)c2)CCN(c2cccc([C@]4(c5nncn5C)C[C@@H](C)C4)c2)C3=O)C1
|
C31H36F3N5O 551.657000 |
PQPUBPMJVGYMCT-FNFPNEPISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB
BindingDB:BDBM226980
|
Local ready
Direct docking supported
|
|
E3L010916
BDB010916
|
US20260008770, Example 4
CC1CC(c2cccc(-c3nc4cc(CN5CCC[C@H](C)C5)cc(C(F)(F)F)c4s3)c2)(c2nncn2C)C1
|
C29H32F3N5S 539.671000 |
SVKMDPUWGYVLJR-VURWPYGMSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM226981; PubChem:CID176895210
|
Local ready
Direct docking supported
|
|
E3L010917
BDB010917
|
US20260008770, Example 5
CC1CC(c2cccc(-c3n[nH]c4c(CN5CCC[C@H](C)C5)cc(C(F)(F)F)nc34)c2)(c2nncn2C)C1
|
C28H32F3N7 523.607000 |
ADZZEZFIHDBJMX-MLMAQJQUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM226982; PubChem:CID176004042
|
Local ready
Direct docking supported
|
|
E3L010918
BDB010918
|
US20260008770, Example 6
CC1CC(c2cccc(-n3ncc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4c3=O)c2)(c2nncn2C)C1
|
C30H33F3N6O 550.629000 |
KLOPCKGKZVLCQU-QORSJFMISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM226983; PubChem:CID178290345
|
Local ready
Direct docking supported
|
|
E3L010919
BDB010919
|
US20260008770, Example 7
CC1CC(c2cccc(-n3cc4c(C(F)(F)F)cc(CN5CCC[C@H](C)C5)cc4n3)c2)(c2nncn2C)C1
|
C29H33F3N6 522.619000 |
VGHDXASNBPIYQI-MPBYYLQUSA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM226984; PubChem:CID178290346
|
Local ready
Direct docking supported
|
|
E3L010920
BDB010920
|
US20260008770, Example 8
CC1CC(c2cccc(-c3nc4cc(CN5CCC[C@H](C)C5)cc(C(F)(F)F)c4n3C)c2)(c2nncn2C)C1
|
C30H35F3N6 536.646000 |
DTBQROBNDOCQGE-QORSJFMISA-N | Q13191 | E3 ubiquitin-protein ligase CBL-B |
BindingDB, PubChem
BindingDB:BDBM226985; PubChem:CID178290347
|
Local ready
Direct docking supported
|