| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L012081
BDB012081
|
BDBM259327
CCN(c1csc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)[C@H]1CC[C@H](N(C)C)CC1
|
C24H36N4O2S 444.645000 |
OEOBFVJMSOTVQD-WGSAOQKQSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM259327
|
Local ready
Direct docking supported
|
|
E3L012082
BDB012082
|
BDBM259328
CCN(c1csc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)[C@H]1CC[C@@H](N(C)C)CC1
|
C24H36N4O2S 444.645000 |
OEOBFVJMSOTVQD-KDURUIRLSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM259328
|
Local ready
Direct docking supported
|
|
E3L012083
BDB012083
|
BDBM259329
CCN(c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1
|
C21H29N3O3S 403.548000 |
JCQDRGZRLNNKJK-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259329; PubChem:CID86764912
|
Local ready
Direct docking supported
|
|
E3L012084
BDB012084
|
BDBM259330
CCN(c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)[C@H]1CC[C@@H](N(C)C)CC1
|
C24H36N4O2S 444.645000 |
XHROKJJCFRMCBT-KDURUIRLSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM259330
|
Local ready
Direct docking supported
|
|
E3L012085
BDB012085
|
BDBM259331
CCN(c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)[C@H]1CC[C@H](N(C)C)CC1
|
C24H36N4O2S 444.645000 |
XHROKJJCFRMCBT-WGSAOQKQSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM259331
|
Local ready
Direct docking supported
|
|
E3L012086
BDB012086
|
BDBM259332
Cc1cc(C)c(CNC(=O)c2cnn(-c3ccccc3)c2C)c(=O)[nH]1
|
C19H20N4O2 336.395000 |
LLWAEAQGDHLXKV-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259332; PubChem:CID34244817
|
Local ready
Direct docking supported
|
|
E3L012087
BDB012087
|
BDBM259333
Cc1cc(C)c(CNC(=O)c2cnn(CC3CCOCC3)c2C)c(=O)[nH]1
|
C19H26N4O3 358.442000 |
NEGOYFGGWMLPMB-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259333; PubChem:CID117679794
|
Local ready
Direct docking supported
|
|
E3L012088
BDB012088
|
BDBM259334
CCN(c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCN(C(=O)OC(C)(C)C)CC1
|
C26H38N4O4S 502.681000 |
ZASAZMPROUJDHA-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259334; PubChem:CID86765023
|
Local ready
Direct docking supported
|
|
E3L012089
BDB012089
|
BDBM259335
CCN(c1scc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCNCC1
|
C21H30N4O2S 402.564000 |
KUJUZLBGRRXLMH-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259335; PubChem:CID86765024
|
Local ready
Direct docking supported
|
|
E3L012090
BDB012090
|
BDBM259336
Cc1cc(C)c(CNC(=O)c2csc(C(C)N3CCC(N(C)C)CC3)c2)c(=O)[nH]1
|
C22H32N4O2S 416.591000 |
MMBRIKLEHZRKNB-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259336; PubChem:CID86765025
|
Local ready
Direct docking supported
|
|
E3L012091
BDB012091
|
BDBM259337
CCN(c1c(C)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)nn1C)C1CCOCC1
|
C21H31N5O3 401.511000 |
IESJTEZXBWQDBI-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259337; PubChem:CID86765026
|
Local ready
Direct docking supported
|
|
E3L012092
BDB012092
|
BDBM259338
CCN(c1scc(C(=O)NCc2c(C(F)(F)F)cc(C)[nH]c2=O)c1C)C1CCOCC1
|
C21H26F3N3O3S 457.518000 |
QSOIBYJLZBCBBB-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259338; PubChem:CID86765027
|
Local ready
Direct docking supported
|
|
E3L012093
BDB012093
|
BDBM259339
CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1csc(N(CC)[C@H]2CC[C@H](N(C)C)CC2)c1C
|
C26H40N4O2S 472.699000 |
KCXYXNRPRRXYDO-MEMLXQNLSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM259339
|
Local ready
Direct docking supported
|
|
E3L012094
BDB012094
|
BDBM259340
CCN(c1scc(C(=O)NCc2c(C)cc(C(F)(F)F)[nH]c2=O)c1C)[C@H]1CC[C@H](N(C)C)CC1
|
C24H33F3N4O2S 498.615000 |
SMXOJCJHWCTJOO-QAQDUYKDSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM259340
|
Local ready
Direct docking supported
|
|
E3L012095
BDB012095
|
BDBM259341
CCN(c1scc(C(=O)NCc2c(OC)cc(C)[nH]c2=O)c1C)[C@H]1CC[C@H](N(C)C)CC1
|
C24H36N4O3S 460.644000 |
OPQWDNJKKMJJBB-IYARVYRRSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB
BindingDB:BDBM259341
|
Local ready
Direct docking supported
|
|
E3L012096
BDB012096
|
BDBM259342
CCN(c1sc(Br)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1
|
C21H28BrN3O3S 482.444000 |
XVRVJNZQOATEAP-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259342; PubChem:CID86763365
|
Local ready
Direct docking supported
|
|
E3L012097
BDB012097
|
BDBM259343
COC(=O)c1csc(C(O)C2CCN(C(=O)OC(C)(C)C)CC2)c1C
|
C18H27NO5S 369.483000 |
HFPTVKCVVCVGRX-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259343; PubChem:CID117679826
|
Local ready
Direct docking supported
|
|
E3L012098
BDB012098
|
BDBM259344
Cc1cc(C)c(CNC(=O)c2csc(C(O)C3CCNCC3)c2C)c(=O)[nH]1
|
C20H27N3O3S 389.521000 |
YGPOYOZOXJDGSV-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259344; PubChem:CID86763367
|
Local ready
Direct docking supported
|
|
E3L012099
BDB012099
|
BDBM259345
Cc1cc(C)c(CNC(=O)c2csc(C3CCCN3C3CCOCC3)c2C)c(=O)[nH]1
|
C23H31N3O3S 429.586000 |
SSGKOEJSQSFNGA-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259345; PubChem:CID86763477
|
Local ready
Direct docking supported
|
|
E3L012100
BDB012100
|
BDBM259346
Cc1cc(C)c(CNC(=O)c2csc(-c3cnn(C4CCNCC4)c3)c2C)c(=O)[nH]1
|
C22H27N5O2S 425.558000 |
FQDJHINNCRAOAE-UHFFFAOYSA-N | O75530, Q09028 | Histone-lysine N-methyltransferase EZH2 |
BindingDB, PubChem
BindingDB:BDBM259346; PubChem:CID86763478
|
Local ready
Direct docking supported
|