| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L013321
BDB013321
|
US9593129, Example 127
CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@H](C(C)C(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H34Cl2N2O5S 581.562000 |
APMPSCTUZKBLRF-BJCQKWEDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299451; PubChem:CID58573310
|
Local ready
Direct docking supported
|
|
E3L013322
BDB013322
|
US9593129, Example 128
CCC(C(=O)OC(C)(C)C)N1C(=O)[C@@](C)(Cc2nnn[nH]2)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H33Cl2N5O3 558.510000 |
JJARPYJBPOGMTN-FAMORDKUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299452; PubChem:CID58573863
|
Local ready
Direct docking supported
|
|
E3L013323
BDB013323
|
US9593129, Example 129
CC[C@@H](CNS(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C25H30Cl2N2O5S 541.497000 |
XITAAXSCXPXQMN-PPWMJIOPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299453; PubChem:CID121336896
|
Local ready
Direct docking supported
|
|
E3L013324
BDB013324
|
US9593129, Example 130
CC[C@@H](CC(C)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C26H29Cl2NO4 490.427000 |
WDFRCALYHDBJRK-DVVDUYQOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299454; PubChem:CID117877008
|
Local ready
Direct docking supported
|
|
E3L013325
BDB013325
|
US9593129, Example 131
CC[C@@H](CC(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C27H33Cl2NO4 506.470000 |
YKVAZXAMPZEUDL-VIJKIUKESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299455; PubChem:CID58573428
|
Local ready
Direct docking supported
|
|
E3L013326
BDB013326
|
US9593129, Example 134
CC[C@@H](CN(C)S(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C26H32Cl2N2O5S 555.524000 |
UHVMWQYGVJLDOF-DVVDUYQOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299458; PubChem:CID58573526
|
Local ready
Direct docking supported
|
|
E3L013327
BDB013327
|
US9593129, Example 136
CC[C@@H](CCC(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C28H35Cl2NO4 520.497000 |
OHUSWLQEUHHUIR-LHHLOQBJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299460; PubChem:CID121336899
|
Local ready
Direct docking supported
|
|
E3L013328
BDB013328
|
US9593129, Example 143
CC[C@@H](CC(O)C(F)(F)F)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H28Cl2F3NO4 546.413000 |
GTVYKDRCOZOWTL-AESUCIHSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299467; PubChem:CID67999875
|
Local ready
Direct docking supported
|
|
E3L013329
BDB013329
|
BDBM299470
CC[C@@H](CC(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H31Cl2NO4 492.443000 |
LWEGKSSGTVFZQX-CETOSCQPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299470; PubChem:CID67999375
|
Local ready
Direct docking supported
|
|
E3L013330
BDB013330
|
US9593129, Example 147
CC[C@@H](CN(CC(F)(F)F)S(C)(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H31Cl2F3N2O5S 623.521000 |
ZPUIHUUGFFPQNO-SODSZRCFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299471; PubChem:CID67999658
|
Local ready
Direct docking supported
|
|
E3L013331
BDB013331
|
US9593129, Example 148
CC[C@@H](CN1CCCS1(=O)=O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H32Cl2N2O5S 567.535000 |
QIMIGYBBXNVAKL-CXQACEEJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299472; PubChem:CID68000723
|
Local ready
Direct docking supported
|
|
E3L013332
BDB013332
|
US9593129, Example 149
CC[C@@H]([C@H](C)C(C)(C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H35Cl2NO4 520.497000 |
WAJGPOYWDHBEGQ-XOYIOBKZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299473; PubChem:CID58573165
|
Local ready
Direct docking supported
|
|
E3L013333
BDB013333
|
US9593129, Example 155
CC[C@H]([C@H](C)O)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C25H29Cl2NO4 478.416000 |
YUALYRLIFVPOHL-STUNAUQMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299479; PubChem:CID121336908
|
Local ready
Direct docking supported
|
|
E3L013334
BDB013334
|
US9593129, Example 158
CC[C@H](O)[C@H](CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C26H31Cl2NO4 492.443000 |
HUGWFCYAKCLYPP-UOIREZJNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299481; PubChem:CID58573749
|
Local ready
Direct docking supported
|
|
E3L013335
BDB013335
|
BDBM299484
CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CC(N)=O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H35Cl2N3O4S 580.578000 |
NTLJDYUONXMSFM-NUWWLQTNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299484; PubChem:CID67998960
|
Local ready
Direct docking supported
|
|
E3L013336
BDB013336
|
US9593129, Example 201
CC[C@@H](CN(C)S(=O)(=O)C1CC1)N1C(=O)[C@@](C)(CCC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C29H36Cl2N2O5S 595.589000 |
NTYBAEOVGORHFO-TYEXZPIASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299524; PubChem:CID121336911
|
Local ready
Direct docking supported
|
|
E3L013337
BDB013337
|
BDBM299527
CC[C@@H](C(=O)CC(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H33Cl2NO4 518.481000 |
XLEZQFNDJNRAQL-MHUJUJBBSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299527; PubChem:CID58574005
|
Local ready
Direct docking supported
|
|
E3L013338
BDB013338
|
US9593129, Example 206
CC[C@@H](CCS(=O)(=O)C(C)C)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H35Cl2NO5S 568.563000 |
RLJDCMYNRQJMNH-ONRXEWETSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299529; PubChem:CID58573226
|
Local ready
Direct docking supported
|
|
E3L013339
BDB013339
|
US9593129, Example 207
CC[C@@H](CCS(=O)(=O)CC1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C29H35Cl2NO5S 580.574000 |
QOOHSEXSGCVVLW-HLBHGXTFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299530; PubChem:CID67999904
|
Local ready
Direct docking supported
|
|
E3L013340
BDB013340
|
US9593129, Example 245
CC(C)[C@@H](c1ccccn1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C29H30Cl2N2O3 525.476000 |
WELWVRMWMNQKHD-DBZWSWGLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299567; PubChem:CID121336917
|
Local ready
Direct docking supported
|