| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L013301
BDB013301
|
US9593129, Example 18
CC[C@@H](COCC(C)(C)O)N1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C27H33Cl2NO5 522.469000 |
HXMZKAQCYSAEMJ-KNEWOZPHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299342; PubChem:CID89877202
|
Local ready
Direct docking supported
|
|
E3L013302
BDB013302
|
US9593129, Example 22
CCNCC(CC)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C25H30Cl2N2O3 477.432000 |
HPLCHNNMRVVPJW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299346; PubChem:CID67999334
|
Local ready
Direct docking supported
|
|
E3L013303
BDB013303
|
US9593129, Example 25
CCC(CN1CCCC1=O)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C27H30Cl2N2O4 517.453000 |
LGMTVRUBURBDTM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299349; PubChem:CID67999129
|
Local ready
Direct docking supported
|
|
E3L013304
BDB013304
|
US9593129, Example 34
CC[C@@H](c1nnc(C)o1)N1C(=O)[C@@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C25H25Cl2N3O4 502.398000 |
JXPCJNIFNLDWFI-PIBIMKELSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299358; PubChem:CID56591372
|
Local ready
Direct docking supported
|
|
E3L013305
BDB013305
|
US9593129, Example 36
O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CCC2)C1=O
|
C24H25Cl2NO3 446.374000 |
BOAYDMWBLSRUAD-JMUQELJHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299360; PubChem:CID56591352
|
Local ready
Direct docking supported
|
|
E3L013306
BDB013306
|
US9593129, Example 42
CCCN1C(=O)[C@H](CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C22H23Cl2NO3 420.336000 |
GRVKUEQTAYRZAX-LDQXTDLNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299366; PubChem:CID56591347
|
Local ready
Direct docking supported
|
|
E3L013307
BDB013307
|
US9593129, Example 47
COC(=O)C[C@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
|
C24H25Cl2NO3 446.374000 |
LSXWGWIINRYFAI-DDVMIGOSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299371; PubChem:CID121336879
|
Local ready
Direct docking supported
|
|
E3L013308
BDB013308
|
US9593129, Example 48
NC(=O)C[C@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
|
C23H24Cl2N2O2 431.363000 |
DZWDWMPZRDOZSQ-IOVLZCAISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299372; PubChem:CID121336880
|
Local ready
Direct docking supported
|
|
E3L013309
BDB013309
|
US9593129, Example 50
O=C(O)CNC(=O)C[C@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
|
C25H26Cl2N2O4 489.399000 |
MWNFYBHJWIHYAM-MAFLHNAESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299374; PubChem:CID121336881
|
Local ready
Direct docking supported
|
|
E3L013310
BDB013310
|
US9593129, Example 51
NNC(=O)C[C@H]1CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
|
C23H25Cl2N3O2 446.378000 |
IKELDMFPSJVDAN-IOVLZCAISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299375; PubChem:CID121336882
|
Local ready
Direct docking supported
|
|
E3L013311
BDB013311
|
BDBM299380
O=C1[C@@H](Cc2nnco2)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N1CC1CC1
|
C24H23Cl2N3O2 456.373000 |
PVQAEXZIYHEIPV-JMUQELJHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299380; PubChem:CID56591194
|
Local ready
Direct docking supported
|
|
E3L013312
BDB013312
|
BDBM299382
CS(=O)(=O)NC(=O)C[C@@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(CC2CC2)C1=O
|
C24H26Cl2N2O4S 509.455000 |
CVPASOLGRPLMES-QTGUNEKASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299382; PubChem:CID56591193
|
Local ready
Direct docking supported
|
|
E3L013313
BDB013313
|
US9593129, Example 63
O=C(O)C[C@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)s2)N(CC2CC2)C1=O
|
C21H21Cl2NO3S 438.376000 |
MJSFAHMLRXGLQG-KKVAFCGZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299387; PubChem:CID56591173
|
Local ready
Direct docking supported
|
|
E3L013314
BDB013314
|
US9593129, Example 64
O=C(O)C[C@@H]1C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)s2)N(CC2CC2)C1=O
|
C21H21Cl2NO3S 438.376000 |
MJSFAHMLRXGLQG-NBQZKYEYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299388; PubChem:CID56591172
|
Local ready
Direct docking supported
|
|
E3L013315
BDB013315
|
US9593129, Example 65
CCOC(=O)[C@H](CC)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C26H29Cl2NO5 506.426000 |
FMTXNTQXGCUMFS-OYAKCLMASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299389; PubChem:CID121336883
|
Local ready
Direct docking supported
|
|
E3L013316
BDB013316
|
US9593129, Example 66
CC[C@@H](C(=O)OC(C)(C)C)N1C(=O)[C@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@H]1c1ccc(Cl)cc1
|
C28H33Cl2NO5 534.480000 |
BTIJKFCQUAULPU-WZRJCJTJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299390; PubChem:CID67998931
|
Local ready
Direct docking supported
|
|
E3L013317
BDB013317
|
US9593129, Example 68
CC[C@@H](COCC1CC1)N1C(=O)[C@@](C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C28H33Cl2NO4 518.481000 |
ZGGWLUDQFJLUIH-DEBQRYJUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299392; PubChem:CID70644525
|
Local ready
Direct docking supported
|
|
E3L013318
BDB013318
|
US9593129, Example 104
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H]2CCCN(CC(F)(F)F)C2)C1=O
|
C27H29Cl2F3N2O3 557.440000 |
QWZBIQPIBZCNPV-HLMLHLEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299428; PubChem:CID58573199
|
Local ready
Direct docking supported
|
|
E3L013319
BDB013319
|
US9593129, Example 106
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C2CC[C@H](O)C2)C1=O
|
C25H27Cl2NO4 476.400000 |
WQURFVOLUVMMKK-LCGPZFEISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299430; PubChem:CID58573804
|
Local ready
Direct docking supported
|
|
E3L013320
BDB013320
|
US9593129, Example 107
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@@H]2CCCOC2)C1=O
|
C25H27Cl2NO4 476.400000 |
QVBYRQZNJPOALG-AFFJLAOCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299431; PubChem:CID56591238
|
Local ready
Direct docking supported
|