| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L013341
BDB013341
|
US9593129, Example 263
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)c2cccs2)C2CC2)C1=O
|
C29H30Cl2N2O5S2 621.608000 |
NIXWEXNCFVDWBK-SKMQWACXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299586; PubChem:CID58573084
|
Local ready
Direct docking supported
|
|
E3L013342
BDB013342
|
US9593129, Example 264
CN(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1)S(=O)(=O)c1cccs1
|
C30H32Cl2N2O5S2 635.635000 |
MYSLCGGRVCUZKN-GVOIKIMQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299587; PubChem:CID58573532
|
Local ready
Direct docking supported
|
|
E3L013343
BDB013343
|
US9593129, Example 265
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)c2ccc(Cl)s2)C2CC2)C1=O
|
C29H29Cl3N2O5S2 656.053000 |
DYUKHMFVQROKNS-HBMCBTENSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299588; PubChem:CID58573927
|
Local ready
Direct docking supported
|
|
E3L013344
BDB013344
|
US9593129, Example 266
CN(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1)S(=O)(=O)c1ccc(Cl)s1
|
C30H31Cl3N2O5S2 670.080000 |
SQVKLCATVKRDMZ-JZQIDANESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299589; PubChem:CID58573391
|
Local ready
Direct docking supported
|
|
E3L013345
BDB013345
|
US9593129, Example 267
CC(C)(C)S(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1)C(F)F
|
C30H36Cl2F2N2O5S 645.596000 |
LWZQFTASTGXTQX-TUQQPOPXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299590; PubChem:CID58574012
|
Local ready
Direct docking supported
|
|
E3L013346
BDB013346
|
US9593129, Example 270
C[C@]1(C2(C(=O)O)CC2)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)C2CC2)C2CC2)C1=O
|
C30H34Cl2N2O5S 605.584000 |
UEIXAPRJBQBMEZ-BLUNXUMHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299593; PubChem:CID58573096
|
Local ready
Direct docking supported
|
|
E3L013347
BDB013347
|
US9593129, Example 272
CCS(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1)c1ccccc1F
|
C33H35Cl2FN2O5S 661.623000 |
RUKZSEPORBCJMK-ZJMXYDMKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299594; PubChem:CID58573293
|
Local ready
Direct docking supported
|
|
E3L013348
BDB013348
|
US9593129, Example 273
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CN(c2ccccc2F)S(C)(=O)=O)C2CC2)C1=O
|
C32H33Cl2FN2O5S 647.596000 |
AVWZEUWSQPZNGD-LTXWUQATSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299595; PubChem:CID58573501
|
Local ready
Direct docking supported
|
|
E3L013349
BDB013349
|
US9593129, Example 274
C[C@]1(CC(=O)O)C[C@H](c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N([C@H](CN(c2ccccc2F)S(=O)(=O)C2CC2)C2CC2)C1=O
|
C34H35Cl2FN2O5S 673.634000 |
OQEGKSPKFPABLK-NQRHSHFRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299596; PubChem:CID121336923
|
Local ready
Direct docking supported
|
|
E3L013350
BDB013350
|
US9593129, Example 275
CCS(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1)c1ccccc1
|
C33H36Cl2N2O5S 643.633000 |
NAKBBRHGPJQAJG-JSFKAFKRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299597; PubChem:CID121336925
|
Local ready
Direct docking supported
|
|
E3L013351
BDB013351
|
US9593129, Example 276
CCS(=O)(=O)NC[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C27H32Cl2N2O5S 567.535000 |
VNHMJRYUJWANED-JAKJZQPHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299598; PubChem:CID121336927
|
Local ready
Direct docking supported
|
|
E3L013352
BDB013352
|
US9593129, Example 277
CCS(=O)(=O)N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1)c1cccc(F)c1
|
C33H35Cl2FN2O5S 661.623000 |
XRGMZTCPBJRAID-JSFKAFKRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299599; PubChem:CID121336928
|
Local ready
Direct docking supported
|
|
E3L013353
BDB013353
|
US9593129, Example 278
[C-]#[N+]c1ccccc1N(C[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1)S(C)(=O)=O
|
C33H33Cl2N3O5S 654.616000 |
QOAQLKTWNCTKNW-ZJMXYDMKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299600; PubChem:CID137528947
|
Local ready
Direct docking supported
|
|
E3L013354
BDB013354
|
US9593129, Example 279
CCCS(=O)(=O)NC[C@H](C1CC1)N1C(=O)[C@@](C)(CC(=O)O)C[C@H](c2cccc(Cl)c2)C1c1ccc(Cl)cc1
|
C28H34Cl2N2O5S 581.562000 |
YRQURMZHHRJRFB-CGLVSNPVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299601; PubChem:CID121336931
|
Local ready
Direct docking supported
|
|
E3L013355
BDB013355
|
US9593129, Example 280
C[C@]1(CC(=O)O)CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(c2ccccc2)S(C)(=O)=O)C2CC2)C1=O
|
C32H34Cl2N2O5S 629.606000 |
NEAMOKMYWTWXQD-BGYXWISYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299602; PubChem:CID117877035
|
Local ready
Direct docking supported
|
|
E3L013356
BDB013356
|
US9593129, Example 281
[C-]#[N+]c1cccc(N(C[C@H](C2CC2)N2C(=O)[C@@](C)(CC(=O)O)CC(c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)S(C)(=O)=O)c1
|
C33H33Cl2N3O5S 654.616000 |
ZZKNRHXOWVNNEF-DWDSGHLUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299603; PubChem:CID137528948
|
Local ready
Direct docking supported
|
|
E3L013357
BDB013357
|
US9593129, Example 282
C[C@]1(CC(=O)O)CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(c2cccnc2)S(C)(=O)=O)C2CC2)C1=O
|
C31H33Cl2N3O5S 630.594000 |
NPCJFISSBFPCIE-CYWCKGBESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299604; PubChem:CID121336932
|
Local ready
Direct docking supported
|
|
E3L013358
BDB013358
|
US9593129, Example 283
C[C@]1(CC(=O)O)CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CN(Cc2cccs2)S(C)(=O)=O)C2CC2)C1=O
|
C31H34Cl2N2O5S2 649.662000 |
ZEZSLCXUXYDVBE-CYWCKGBESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299605; PubChem:CID121336934
|
Local ready
Direct docking supported
|
|
E3L013359
BDB013359
|
US9593129, Example 284
COc1cccc(CN(C[C@H](C2CC2)N2C(=O)[C@@](C)(CC(=O)O)CC(c3cccc(Cl)c3)[C@H]2c2ccc(Cl)cc2)S(C)(=O)=O)c1
|
C34H38Cl2N2O6S 673.659000 |
YRLUTAIFRDBPFM-RIBPYBQCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299606; PubChem:CID121336936
|
Local ready
Direct docking supported
|
|
E3L013360
BDB013360
|
US9593129, Example 285
C[C@]1(CC(=O)O)CC(c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N([C@H](CNS(=O)(=O)Cc2ccccc2)C2CC2)C1=O
|
C32H34Cl2N2O5S 629.606000 |
VCLKYYIVEHNXSL-BGYXWISYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM299607; PubChem:CID121336938
|
Local ready
Direct docking supported
|