| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L018141
BDB018141
|
US10570140, Example 26
C[C@@]1(O)[C@@H]([C@H](O)c2ccc(Cl)cc2)O[C@@H](n2ccc3c(N)ncnc32)[C@@H]1O
|
C18H19ClN4O4 390.827000 |
FFQLPKBDTZBCDL-FOOXYVKASA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435560; PubChem:CID137479654
|
Local ready
Direct docking supported
|
|
E3L018142
BDB018142
|
US10570140, Example 32
CO/N=C1\NC=NC2C1C=CN2[C@@H]1O[C@H](COc2ccc3ccc(N)nc3c2)[C@@](C)(O)[C@H]1O
|
C22H26N6O5 454.487000 |
ZGEWUHKMLCRENE-TUTNCRRQSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435571; PubChem:CID137495454
|
Local ready
Direct docking supported
|
|
E3L018143
BDB018143
|
US10570140, Example 37
CONc1ncnc2c1ccn2[C@@H]1O[C@H]([C@H](O)c2ccc(Cl)c(Cl)c2)[C@@](C)(O)[C@H]1O
|
C19H20Cl2N4O5 455.298000 |
DTWHQWQFELEBBH-MXQZZYIMSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435572; PubChem:CID137479650
|
Local ready
Direct docking supported
|
|
E3L018144
BDB018144
|
US10570140, Example 40
CNc1ncnc2c1ccn2[C@@H]1O[C@H](CSC)[C@@](C)(O)[C@H]1O
|
C14H20N4O3S 324.406000 |
MLIJDSYMNNILFK-RDBQEKCUSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435601; PubChem:CID137479711
|
Local ready
Direct docking supported
|
|
E3L018145
BDB018145
|
US10570140, Example 41
C[C@@]1(O)[C@@H](COc2cccc(NC(N)=O)c2)O[C@@H](n2ccc3c(Cl)ncnc32)[C@@H]1O
|
C19H20ClN5O5 433.852000 |
NLZYJCHHPGGQAC-QOIYZWAUSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435602; PubChem:CID137479761
|
Local ready
Direct docking supported
|
|
E3L018146
BDB018146
|
US10570140, Example 42
C[C@@]1(O)[C@@H](C(=O)Nc2cccc(CN)c2)O[C@@H](n2ccc3c(Cl)ncnc32)[C@@H]1O
|
C19H20ClN5O4 417.853000 |
FWCLXDKNWVVBOW-RAKLQZGLSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435608; PubChem:CID137479760
|
Local ready
Direct docking supported
|
|
E3L018147
BDB018147
|
US10570140, Example 43
C[C@@]1(O)[C@@H](C(=O)Nc2cccc(CN)c2)O[C@@H](n2ccc3c(N)ncnc32)[C@@H]1O
|
C19H22N6O4 398.423000 |
UDIXSGFSZTVKMT-RAKLQZGLSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435617; PubChem:CID137479641
|
Local ready
Direct docking supported
|
|
E3L018148
BDB018148
|
BDBM435619
CO/N=c1\[nH]cnc2c1ccn2[C@@H]1O[C@H]([C@H](O)c2ccc(Cl)cc2)[C@@](C)(O)[C@H]1O
|
C19H21ClN4O5 420.853000 |
IILNTZKONQGIJN-MXQZZYIMSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435619; PubChem:CID137479662
|
Local ready
Direct docking supported
|
|
E3L018149
BDB018149
|
BDBM435630
CO/N=c1\[nH]cnc2c1ccn2[C@@H]1O[C@H](COc2ccc3ccc(NOC)nc3c2)[C@@](C)(O)[C@H]1O
|
C23H26N6O6 482.497000 |
KJPJWKFOPWVXEL-ANEJOOLBSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435630; PubChem:CID137479682
|
Local ready
Direct docking supported
|
|
E3L018150
BDB018150
|
BDBM435650 | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB
BindingDB:BDBM435650
|
Needs structure
Structure source missing
|
||
|
E3L018151
BDB018151
|
Prmt5-IN-14
C[C@@]1(O)[C@@H]([C@H](O)c2ccc(Cl)c(Cl)c2)O[C@@H](n2ccc3c(N)ncnc32)[C@@H]1O
|
C18H18Cl2N4O4 425.272000 |
NVZVVFMXEHOMQR-FOOXYVKASA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435651; PubChem:CID137479770
|
Local ready
Direct docking supported
|
|
E3L018152
BDB018152
|
US10570140, Example 49
C[C@@]1(O)[C@@H](Cc2ccc3c(c2)OCO3)O[C@@H](n2ccc3c(N)ncnc32)[C@@H]1O
|
C19H20N4O5 384.392000 |
YQLFBSKSTZBEAG-WTLGNFPFSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435652; PubChem:CID137479643
|
Local ready
Direct docking supported
|
|
E3L018153
BDB018153
|
US10570140, Example 50
C[C@@]1(O)[C@@H](Cc2ccc(Cl)c(Cl)c2)O[C@@H](n2ccc3c(N)ncnc32)[C@@H]1O
|
C18H18Cl2N4O3 409.273000 |
HWWZSLIRECKJAG-LTCOOKNTSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435653; PubChem:CID137479695
|
Local ready
Direct docking supported
|
|
E3L018154
BDB018154
|
US10570140, Example 51
C[C@@]1(O)[C@@H](Cc2ccc(Cl)c(Cl)c2)O[C@@H](n2ccc3cncnc32)[C@@H]1O
|
C18H17Cl2N3O3 394.258000 |
VUHLROWQIKJYLB-CYGHRXIMSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435654; PubChem:CID137479670
|
Local ready
Direct docking supported
|
|
E3L018155
BDB018155
|
US10570140, Example 53
C[C@@]1(O)[C@@H](COc2ccc3cccnc3c2)O[C@@H](n2ccc3c(N)ncnc32)[C@@H]1O
|
C21H21N5O4 407.430000 |
JWZDBSDWWKOHJH-HRQSHJORSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435655; PubChem:CID137479637
|
Local ready
Direct docking supported
|
|
E3L018156
BDB018156
|
US10570140, Example 54
Cc1ncnc2c1ccn2[C@@H]1O[C@H](COc2ccc3cccnc3c2)[C@@](C)(O)[C@H]1O
|
C22H22N4O4 406.442000 |
WSVHMMAGEIESKK-NPDDRXJXSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435656; PubChem:CID137479713
|
Local ready
Direct docking supported
|
|
E3L018157
BDB018157
|
US10570140, Example 55
Cc1ncnc2c1ccn2[C@@H]1O[C@H](COc2ccc3cc(Br)c(N)nc3c2)[C@@](C)(O)[C@H]1O
|
C22H22BrN5O4 500.353000 |
WNAZWXPYATUMBE-GMQQQROESA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435657; PubChem:CID137479703
|
Local ready
Direct docking supported
|
|
E3L018158
BDB018158
|
US10570140, Example 56
Cc1cc([C@@H](O)[C@H]2O[C@@H](n3ccc4c(N)ncnc43)[C@H](O)[C@]2(C)O)ccc1Cl
|
C19H21ClN4O4 404.854000 |
MZZBXEBGPWKZNM-MXQZZYIMSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435658; PubChem:CID137479633
|
Local ready
Direct docking supported
|
|
E3L018159
BDB018159
|
US10570140, Example 57
Cc1cc([C@@H](O)[C@H]2O[C@@H](n3ccc4c(C)ncnc43)[C@H](O)[C@]2(C)O)ccc1Cl
|
C20H22ClN3O4 403.866000 |
LMQXLKNSRLIXHZ-DSJDWBEOSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435659; PubChem:CID137479775
|
Local ready
Direct docking supported
|
|
E3L018160
BDB018160
|
US10570140, Example 58
Cc1ncnc2c1ccn2[C@@H]1O[C@H]([C@H](O)c2ccc(Cl)c(Cl)c2)[C@@](C)(O)[C@H]1O
|
C19H19Cl2N3O4 424.284000 |
PNEWSTDPFYPNQM-DARIXABFSA-N | Q9BQA1 | Protein arginine N-methyltransferase 5 |
BindingDB, PubChem
BindingDB:BDBM435700; PubChem:CID137479653
|
Local ready
Direct docking supported
|