| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L002141
BDB002141
|
BDBM43348
COCc1cc(=O)[nH]c(Nc2nc3ccc(C)cc3o2)n1
|
C14H14N4O3 286.291000 |
AYNYOFBZPWQVCY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43348; PubChem:CID135449568
|
Local ready
Direct docking supported
|
|
E3L002142
BDB002142
|
BDBM43349
Cc1noc(C)c1COc1ccc(C(=O)NCc2ccccn2)cc1
|
C19H19N3O3 337.379000 |
MFVSGCDPMIOOIT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43349; PubChem:CID2495025
|
Local ready
Direct docking supported
|
|
E3L002143
BDB002143
|
BDBM43350
Cc1cc(C(=O)CSc2nnc(Nc3ccccc3)s2)c(C)n1CC1CCCO1
|
C21H24N4O2S2 428.583000 |
VZZHIVBYNGMNNV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43350; PubChem:CID2998364
|
Local ready
Direct docking supported
|
|
E3L002144
BDB002144
|
BDBM43351
COc1ccc(CCNC(=O)COC(=O)c2cnc(C)cn2)cc1OC
|
C18H21N3O5 359.382000 |
VWNURLMOQLQHOD-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43351; PubChem:CID2356467
|
Local ready
Direct docking supported
|
|
E3L002145
BDB002145
|
BDBM43352
O=C(COC(=O)C1CCCC1)c1ccc(OC(F)F)cc1
|
C15H16F2O4 298.285000 |
MHERCEKEGNPUKX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43352; PubChem:CID2357650
|
Local ready
Direct docking supported
|
|
E3L002146
BDB002146
|
BDBM43353
COc1ccc(C2C(C(=O)N3CCCCC3)CCC(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1
|
C27H34N2O6 482.577000 |
QAICVUGPWYZAJL-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43353; PubChem:CID3237621
|
Local ready
Direct docking supported
|
|
E3L002147
BDB002147
|
BDBM43354
CC1(C)CC(=O)C2C(=Nc3nc(SCCN4CCOCC4)[nH]c(=O)c3C2c2cccs2)C1
|
C23H28N4O3S2 472.636000 |
POKCCZYJWPEPSZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43354; PubChem:CID136666233
|
Local ready
Direct docking supported
|
|
E3L002148
BDB002148
|
BDBM43355
N#Cc1c(N)nc2c(c1-c1cccc(O)c1)CCCCCC2
|
C18H19N3O 293.370000 |
VRWSXZOFFNRTBA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43355; PubChem:CID3243795
|
Local ready
Direct docking supported
|
|
E3L002149
BDB002149
|
BDBM43356
COc1ccc(C)cc1S(=O)(=O)N(C)CC(=O)NC1CCCCC1
|
C17H26N2O4S 354.472000 |
FCVJXOUNTRJNCI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43356; PubChem:CID2237015
|
Local ready
Direct docking supported
|
|
E3L002150
BDB002150
|
BDBM43357
CN(C)c1oc(-c2ccccc2Cl)nc1C#N
|
C12H10ClN3O 247.685000 |
HFRAYEALNRDZAA-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43357; PubChem:CID891940
|
Local ready
Direct docking supported
|
|
E3L002151
BDB002151
|
BDBM43358
O=C(O)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1ccccc1[S+]2[O-]
|
C21H14FNO4S 395.411000 |
PLLOPZCELZQFPM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43358; PubChem:CID5307699
|
Local ready
Direct docking supported
|
|
E3L002152
BDB002152
|
BDBM43359
O=C(Nc1nnc(-c2ccc(Cl)cc2)o1)c1ccccc1Br
|
C15H9BrClN3O2 378.613000 |
ONZZORAJENSXMQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43359; PubChem:CID3315017
|
Local ready
Direct docking supported
|
|
E3L002153
BDB002153
|
BDBM43360
Cc1cc(NC(=O)CSc2nc(C(C)C)nc3c2c(=O)n(C)c(=O)n3C)no1
|
C17H20N6O4S 404.452000 |
KOKDVHCQXPDERJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43360; PubChem:CID5310263
|
Local ready
Direct docking supported
|
|
E3L002154
BDB002154
|
BDBM43361
CC(=O)c1ccc(OCC(O)Cn2nnc3ccccc32)cc1
|
C17H17N3O3 311.341000 |
LUYKGTSKGPXRPZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43361; PubChem:CID2917526
|
Local ready
Direct docking supported
|
|
E3L002155
BDB002155
|
Thiram
CN(C)C(=S)SSC(=S)N(C)C
|
C6H12N2S4 240.444000 |
KUAZQDVKQLNFPE-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43362; PubChem:CID5455
|
Local ready
Direct docking supported
|
|
E3L002156
BDB002156
|
BDBM43363
O=C1C(Cl)=C(N2CCCCC2)C(=O)C(Cl)=C1c1cnc(N2CCCCC2)s1
|
C19H21Cl2N3O2S 426.369000 |
TVYNWNKQFPNOBT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43363; PubChem:CID406171
|
Local ready
Direct docking supported
|
|
E3L002157
BDB002157
|
BDBM43364
COc1ccc(-c2nc(C)c(C(C)=O)n2O)cc1
|
C13H14N2O3 246.266000 |
FIMVOUAMAMVCTN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43364; PubChem:CID1082694
|
Local ready
Direct docking supported
|
|
E3L002158
BDB002158
|
BDBM43365
Cn1c(=O)[nH]c(=O)c2c1nc(Br)n2CCCc1ccccc1
|
C15H15BrN4O2 363.215000 |
RXKCKKUYDBEQFO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43365; PubChem:CID1119323
|
Local ready
Direct docking supported
|
|
E3L002159
BDB002159
|
BDBM43366
CC(C)c1ccc2c(c1)C1(NN=C(c3ccccc3)S1)C(=O)N2
|
C18H17N3OS 323.421000 |
HAUQIWOBYGUGLK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43366; PubChem:CID3154392
|
Local ready
Direct docking supported
|
|
E3L002160
BDB002160
|
BDBM43367
Cc1cc2ncn(C(=O)N3CCC(C)CC3)c2cc1C
|
C16H21N3O 271.364000 |
VOWBZMVBYGELAY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43367; PubChem:CID888939
|
Local ready
Direct docking supported
|