| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L002201
BDB002201
|
BDBM43408
NC(=O)c1c(NC(=O)C2CCCO2)sc2c1CCCC2
|
C14H18N2O3S 294.376000 |
LCHVRVJNBNSFHV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43408; PubChem:CID2789559
|
Local ready
Direct docking supported
|
|
E3L002202
BDB002202
|
BDBM43409
Cc1ccc(-n2c(C)cc(C=C3C(=O)CC(C)(C)CC3=O)c2C)cc1
|
C22H25NO2 335.447000 |
VOKIGYWNBZPHBS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43409; PubChem:CID2337848
|
Local ready
Direct docking supported
|
|
E3L002203
BDB002203
|
BDBM43410
COc1ccc(-c2nsc(SCC(=O)Nc3ccc4c(c3)OCO4)n2)cc1
|
C18H15N3O4S2 401.469000 |
DTRMPGOCLNBTDM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43410; PubChem:CID5066968
|
Local ready
Direct docking supported
|
|
E3L002204
BDB002204
|
N-(morpholine-4-carbothioyl)-4-propan-2-yloxybenzamide
CC(C)Oc1ccc(C(=O)NC(=S)N2CCOCC2)cc1
|
C15H20N2O3S 308.403000 |
KDTMQTFCIGQXML-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43411; PubChem:CID880334
|
Local ready
Direct docking supported
|
|
E3L002205
BDB002205
|
BDBM43412
COc1ccc(/C=C/C(=O)Nc2ccc(C34CC5CC(CC(O)(C5)C3)C4)cc2)cc1OC
|
C27H31NO4 433.548000 |
ZELMMSPIUCEQGT-ONNFQVAWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43412; PubChem:CID5786057
|
Local ready
Direct docking supported
|
|
E3L002206
BDB002206
|
3H-Indole, 2-(2-methoxy-5-methylphenyl)-3,3-dimethyl-
COc1ccc(C)cc1C1=Nc2ccccc2C1(C)C
|
C18H19NO 265.356000 |
RWCDZKHBJGXNQH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43413; PubChem:CID828259
|
Local ready
Direct docking supported
|
|
E3L002207
BDB002207
|
BDBM43414
Cc1nn(-c2nnc(NCc3ccccc3)nn2)c(C)c1Br
|
C14H14BrN7 360.219000 |
JNLZCWHGFZEMCI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43414; PubChem:CID1046666
|
Local ready
Direct docking supported
|
|
E3L002208
BDB002208
|
BDBM43415
Cc1ccccc1Nc1nnc(SCC2CCCCO2)s1
|
C15H19N3OS2 321.471000 |
WWZSUUWEGNXGHP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43415; PubChem:CID3977504
|
Local ready
Direct docking supported
|
|
E3L002209
BDB002209
|
BDBM43416
CC(NC(=O)Cn1ncc(Cl)c(Cl)c1=O)C12CC3CC(CC(C3)C1)C2
|
C18H23Cl2N3O2 384.307000 |
YUKMHBBXSAOJDN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43416; PubChem:CID4811966
|
Local ready
Direct docking supported
|
|
E3L002210
BDB002210
|
BDBM43417
C=CCN(c1cccc(C(F)(F)F)c1)S(=O)(=O)c1cccc(C(=O)OCC(=O)NCCC)c1
|
C22H23F3N2O5S 484.496000 |
DIQNZGBWAVZDFM-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43417; PubChem:CID4370317
|
Local ready
Direct docking supported
|
|
E3L002211
BDB002211
|
BDBM43418
COc1ccc(C)cc1NC(=O)C(OC(=O)CNC(=O)c1cc(C)cc(C)c1)c1ccccc1
|
C27H28N2O5 460.530000 |
PLXHCDPVOCPDMH-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43418; PubChem:CID4660908
|
Local ready
Direct docking supported
|
|
E3L002212
BDB002212
|
BDBM43419
Cc1ccc(C)c(NC(=O)C(Sc2nnc(-c3cccs3)o2)c2ccccc2)c1
|
C22H19N3O2S2 421.547000 |
LGIFHGBAMCQMJP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43419; PubChem:CID4664882
|
Local ready
Direct docking supported
|
|
E3L002213
BDB002213
|
BDBM43420
Cc1cccc(Nc2nnc(SCC3CCCCO3)s2)c1C
|
C16H21N3OS2 335.498000 |
LWHZXHXWPGGLJN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43420; PubChem:CID15945197
|
Local ready
Direct docking supported
|
|
E3L002214
BDB002214
|
BDBM43421
Cc1cccc(Nc2nnc(SCC3CCCCO3)s2)c1
|
C15H19N3OS2 321.471000 |
OJDODSHGHIABNJ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43421; PubChem:CID15945209
|
Local ready
Direct docking supported
|
|
E3L002215
BDB002215
|
BDBM43422
COCCNC(=O)/C(C#N)=C/c1cccc(/C=C(\C#N)C(=O)NCCOC)c1
|
C20H22N4O4 382.420000 |
MALDNJQLXTVBES-JYFOCSDGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43422; PubChem:CID2423595
|
Local ready
Direct docking supported
|
|
E3L002216
BDB002216
|
BDBM43423
COc1ccccc1OCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1N1CCCCC1
|
C25H33N3O5S 487.622000 |
KCAXKKFYABLRDV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43423; PubChem:CID4880558
|
Local ready
Direct docking supported
|
|
E3L002217
BDB002217
|
BDBM43424
O=C(Cn1ncc(Cl)c(Cl)c1=O)NCC1CCCCC1
|
C13H17Cl2N3O2 318.204000 |
VJTYXYHEDHOHEI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43424; PubChem:CID2585197
|
Local ready
Direct docking supported
|
|
E3L002218
BDB002218
|
BDBM43425
Clc1ccccc1C=NNC1=Nc2cccc3cccc1c23
|
C18H12ClN3 305.768000 |
GWWLAHNKGIJBJK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM43425
|
Local ready
Direct docking supported
|
|
E3L002219
BDB002219
|
BDBM43426
Cc1nnc(SCCN2CCOCC2)c2nn(-c3ccccc3F)c(C)c12
|
C19H22FN5OS 387.484000 |
CZTYNKFSRSTALT-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43426; PubChem:CID990454
|
Local ready
Direct docking supported
|
|
E3L002220
BDB002220
|
BDBM43427
COc1ccccc1-c1cc(SC)c(C#N)c(=O)o1
|
C14H11NO3S 273.313000 |
OUQLNLLIMKLHQP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43427; PubChem:CID902188
|
Local ready
Direct docking supported
|