| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L002161
BDB002161
|
BDBM43368
CC(=O)NC(SC(=S)N(C)C)C(Cl)(Cl)Cl
|
C7H11Cl3N2OS2 309.671000 |
DFTATZQBDBNHLQ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43368; PubChem:CID3490047
|
Local ready
Direct docking supported
|
|
E3L002162
BDB002162
|
BDBM43369
Cc1cc(C)c(S(=O)(=O)c2ccccc2)c(OC(=O)c2cc(F)c(F)cc2Cl)n1
|
C20H14ClF2NO4S 437.851000 |
OUADNAYNVDLFHV-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43369; PubChem:CID1478960
|
Local ready
Direct docking supported
|
|
E3L002163
BDB002163
|
BDBM43370
CCn1c(=O)n(CC(=O)Nc2cc(OC)c(OC)c(OC)c2)c(=O)c2ccccc21
|
C21H23N3O6 413.430000 |
LFCYMTGPDJIGPP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43370; PubChem:CID5146720
|
Local ready
Direct docking supported
|
|
E3L002164
BDB002164
|
BDBM43371
CCCN(CCC)CCNc1c(NC2CCN(C(=O)OCC)CC2)c(=O)c1=O
|
C20H34N4O4 394.516000 |
SBBYGPARXQSZIO-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43371; PubChem:CID9550915
|
Local ready
Direct docking supported
|
|
E3L002165
BDB002165
|
BDBM43372
COc1ccc2[nH]c3c(N4CC(C)OC(C)C4)ncnc3c2c1
|
C17H20N4O2 312.373000 |
MLRGEVJLYZMGCW-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43372; PubChem:CID3832575
|
Local ready
Direct docking supported
|
|
E3L002166
BDB002166
|
BDBM43373
COC(=O)CSC1=C(C#N)C(=O)NC(c2ccccc2)S1
|
C14H12N2O3S2 320.395000 |
BMVMKTNMDRHJOF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43373; PubChem:CID3512464
|
Local ready
Direct docking supported
|
|
E3L002167
BDB002167
|
BDBM43374
C=C(C)c1sc(N2CCN(c3cccc(C(F)(F)F)c3)CC2)nc1O
|
C17H18F3N3OS 369.412000 |
UHPRPTHKQAKXGK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43374; PubChem:CID91896563
|
Local ready
Direct docking supported
|
|
E3L002168
BDB002168
|
BDBM43375
CCOC(=O)C1=C(c2ccccc2)O/C(=C(/C#N)C(F)(F)F)S1
|
C15H10F3NO3S 341.310000 |
XYSDWCDTJKHDGV-GXDHUFHOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43375; PubChem:CID1883255
|
Local ready
Direct docking supported
|
|
E3L002169
BDB002169
|
BDBM43376
CCN1CCN(C(=O)CCc2nc3ccccc3c(=O)[nH]2)CC1
|
C17H22N4O2 314.389000 |
NCHDBTQLQOPVSN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43376; PubChem:CID135413937
|
Local ready
Direct docking supported
|
|
E3L002170
BDB002170
|
BDBM43377
CCN(CC(=O)Nc1ccc(N2CCOCC2)cc1)Cc1nc2ccccc2c(=O)[nH]1
|
C23H27N5O3 421.501000 |
DZWLZPWRNXQUGF-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43377; PubChem:CID135441010
|
Local ready
Direct docking supported
|
|
E3L002171
BDB002171
|
N-benzyl-2-(4-pyrimidin-2-ylpiperazin-1-yl)acetamide
O=C(CN1CCN(c2ncccn2)CC1)NCc1ccccc1
|
C17H21N5O 311.389000 |
JEMTWDLGKLDSJI-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43378; PubChem:CID2546490
|
Local ready
Direct docking supported
|
|
E3L002172
BDB002172
|
BDBM43379
O=C(COC(=O)c1ccccc1C(=O)c1ccc(Cl)c([N+](=O)[O-])c1)NC1CCCCCC1
|
C23H23ClN2O6 458.898000 |
AWEVAFGPTHYXOX-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43379; PubChem:CID2371253
|
Local ready
Direct docking supported
|
|
E3L002173
BDB002173
|
BDBM43380
CC(=O)Nc1ccc(S(=O)(=O)N(C)CC(=O)OCC(=O)N2CCc3ccccc32)cc1
|
C21H23N3O6S 445.497000 |
BIYUXDKFQVZQMP-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43380; PubChem:CID2475617
|
Local ready
Direct docking supported
|
|
E3L002174
BDB002174
|
BDBM43381
COc1cccc(OC)c1C(=O)NNC(=O)c1cccc(COc2ccc3c(c2)CCC3)c1
|
C26H26N2O5 446.503000 |
IBLBYMOMDRCDFN-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43381; PubChem:CID1000056
|
Local ready
Direct docking supported
|
|
E3L002175
BDB002175
|
BDBM43382
O=C(NN=Cc1ccc(Cl)s1)c1cccs1
|
C10H7ClN2OS2 270.766000 |
BUGOOFSOJZTYDK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM43382
|
Local ready
Direct docking supported
|
|
E3L002176
BDB002176
|
BDBM43383
CCSc1nc2ccccc2n1C(=O)/C=C\c1ccc(OC)c(OC)c1
|
C20H20N2O3S 368.458000 |
NJKXCECKMAPPHS-BENRWUELSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43383; PubChem:CID7285210
|
Local ready
Direct docking supported
|
|
E3L002177
BDB002177
|
BDBM43384
CN(C)c1cc(C(F)(F)F)nc(-c2ccccn2)n1
|
C12H11F3N4 268.242000 |
QRXYEEIFPRNCHK-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43384; PubChem:CID1475712
|
Local ready
Direct docking supported
|
|
E3L002178
BDB002178
|
BDBM43385
O=C(Nc1ccc(Cl)cc1)c1ccc(-n2cccn2)c([N+](=O)[O-])c1
|
C16H11ClN4O3 342.742000 |
HBDDACULCCXCBS-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43385; PubChem:CID3778594
|
Local ready
Direct docking supported
|
|
E3L002179
BDB002179
|
BDBM43386
C=CCSc1nc2ccccc2n1C(=O)/C=C/c1cc(OC)c(OC)c(OC)c1
|
C22H22N2O4S 410.495000 |
JMBYFKBGOMJGFM-ZHACJKMWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43386; PubChem:CID5737516
|
Local ready
Direct docking supported
|
|
E3L002180
BDB002180
|
BDBM43387
CC(C)CC(=O)C=Cn1c(=S)oc2ccccc21
|
C14H15NO2S 261.346000 |
MFSKFEMERYYCSZ-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM43387; PubChem:CID3093017
|
Local ready
Direct docking supported
|