| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L023001
BDB023001
|
BDBM530412
CO[C@H]1CC[C@H](Nc2ncc3c(n2)CN(C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)[C@H]2C[C@@H]32)CC1
|
C28H37N5O2 475.637000 |
NWQXULCLHZFMAJ-KNCNJFNZSA-N | P51948 | Cyclin-H |
BindingDB
BindingDB:BDBM530412
|
Local ready
Direct docking supported
|
|
E3L023002
BDB023002
|
BDBM530413
Cc1cccc([C@@H]2CN(C)CC[C@H]2C(=O)N2Cc3nc(Nc4cnn(C)c4)ncc3[C@@H]3C[C@@H]32)c1
|
C26H31N7O 457.582000 |
MJGXMKHXJHQKDV-RDCABSMISA-N | P51948 | Cyclin-H |
BindingDB
BindingDB:BDBM530413
|
Local ready
Direct docking supported
|
|
E3L023003
BDB023003
|
BDBM530414
Cc1cccc([C@H]2CN(C)CC[C@@H]2C(=O)N2Cc3nc(Nc4cnn(C)c4)ncc3[C@@H]3C[C@@H]32)c1
|
C26H31N7O 457.582000 |
MJGXMKHXJHQKDV-QRVLJTFESA-N | P51948 | Cyclin-H |
BindingDB
BindingDB:BDBM530414
|
Local ready
Direct docking supported
|
|
E3L023004
BDB023004
|
BDBM530415
C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1
|
C25H34N6O2 450.587000 |
VCDXKVSUQVNUPB-WZONZLPQSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530415; PubChem:CID163200344
|
Local ready
Direct docking supported
|
|
E3L023005
BDB023005
|
BDBM530416
CN1CCN(C(=O)N2Cc3nc(NC4CCOCC4)ncc3CC2(C)C)[C@@H](c2ccccc2)C1
|
C26H36N6O2 464.614000 |
FOBMBELMBHICIM-HSZRJFAPSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530416; PubChem:CID163200345
|
Local ready
Direct docking supported
|
|
E3L023006
BDB023006
|
BDBM530417
CC(C)N1CCN(C(=O)N2Cc3nc(NC4CCOCC4)ncc3C[C@H]2C)[C@@H](c2ccccc2)C1
|
C27H38N6O2 478.641000 |
OTQKMFXZFVQNPD-CJFMBICVSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530417; PubChem:CID163200346
|
Local ready
Direct docking supported
|
|
E3L023007
BDB023007
|
BDBM530418
C[C@H]1Cc2cnc(NC3(c4ccccc4)COC3)cc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1
|
C31H36N4O2 496.655000 |
SBXUVFLJUOJULC-QLCOJLISSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530418; PubChem:CID163200347
|
Local ready
Direct docking supported
|
|
E3L023008
BDB023008
|
BDBM530419
C[C@H]1Cc2cnc(Nc3cnn(C)c3)cc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1
|
C26H32N6O 444.583000 |
ZSPKGLQDWCDKNG-GKVQRAMASA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530419; PubChem:CID163200348
|
Local ready
Direct docking supported
|
|
E3L023009
BDB023009
|
BDBM530420
CO[C@H]1CC[C@H](Nc2cc3c(cn2)C[C@H](C)N(C(=O)C2CCN(C)CC2c2cccc(C)c2)C3)CC1
|
C30H42N4O2 490.692000 |
VYPXLUSXPNXRRO-FSSQJUNMSA-N | P51948 | Cyclin-H |
BindingDB
BindingDB:BDBM530420
|
Local ready
Direct docking supported
|
|
E3L023010
BDB023010
|
BDBM530421
CO[C@H]1CC[C@H](Nc2cc3c(cn2)C[C@H](C)N(C(=O)[C@@H]2CCN(C)C[C@H]2c2cccc(C)c2)C3)CC1
|
C30H42N4O2 490.692000 |
VYPXLUSXPNXRRO-BKNMONHFSA-N | P51948 | Cyclin-H |
BindingDB
BindingDB:BDBM530421
|
Local ready
Direct docking supported
|
|
E3L023011
BDB023011
|
BDBM530422
C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCNC[C@@H]1c1ccccc1
|
C24H32N6O2 436.560000 |
AOPULEPXSRWMEU-VGOFRKELSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530422; PubChem:CID163200351
|
Local ready
Direct docking supported
|
|
E3L023012
BDB023012
|
BDBM530423
C[C@@H]1Cc2cnc(NC3CCN(S(C)(=O)=O)CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1
|
C26H37N7O3S 527.695000 |
SNWVMKZGGAITBS-NTKDMRAZSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530423; PubChem:CID163200352
|
Local ready
Direct docking supported
|
|
E3L023013
BDB023013
|
BDBM530424
C[C@@H]1Cc2cnc(NC3CCN(S(=O)(=O)C4CC4)CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1
|
C28H39N7O3S 553.733000 |
KGUMFAWGZPNUEW-FQRUVTKNSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530424; PubChem:CID163200353
|
Local ready
Direct docking supported
|
|
E3L023014
BDB023014
|
BDBM530425
C[C@@H]1Cc2cnc(NC3CCN(S(=O)(=O)N(C)C)CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1
|
C27H40N8O3S 556.737000 |
SEGFKKZKDIJBSY-CJFMBICVSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530425; PubChem:CID163200354
|
Local ready
Direct docking supported
|
|
E3L023015
BDB023015
|
BDBM530426
C[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCN(C)C[C@H]1c1cccc(F)c1
|
C25H33FN6O2 468.577000 |
BLLZHXZECKWOMV-SBUREZEXSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530426; PubChem:CID163200355
|
Local ready
Direct docking supported
|
|
E3L023016
BDB023016
|
BDBM530427
C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1
|
C25H32N8O 460.586000 |
PAMKRBCAEQZZRE-WZONZLPQSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530427; PubChem:CID163200356
|
Local ready
Direct docking supported
|
|
E3L023017
BDB023017
|
BDBM530428
C[C@@H]1Cc2cnc(NC3CCS(=O)(=O)CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1
|
C25H34N6O3S 498.653000 |
VINIZKSQBWUQIG-WZONZLPQSA-N | P51948 | Cyclin-H |
BindingDB, PubChem
BindingDB:BDBM530428; PubChem:CID163200357
|
Local ready
Direct docking supported
|
|
E3L023018
BDB023018
|
US11207325, Example 110
OCCC1CCN(CCc2ccc(-c3cnc(NCc4cccc5c4CCO5)n4cnnc34)cn2)CC1
|
C28H33N7O2 499.619000 |
LYOFYQHRLNMKFX-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM531187; PubChem:CID155206297
|
Local ready
Direct docking supported
|
|
E3L023019
BDB023019
|
US11207325, Example 148
CC(C)n1cc(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cnnc23)c(C(F)(F)F)n1
|
C21H19F4N7O 461.423000 |
OJEVEQVEKLNTSJ-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM531225; PubChem:CID121432904
|
Local ready
Direct docking supported
|
|
E3L023020
BDB023020
|
US11207325, Example 159
COCCn1nc(C)c(-c2cnc(NCc3c(F)ccc4c3CCO4)n3cnnc23)c1C
|
C22H24FN7O2 437.479000 |
QQNPDWBNYQVGAI-UHFFFAOYSA-N | O75530 | Polycomb protein EED |
BindingDB, PubChem
BindingDB:BDBM531236; PubChem:CID121433078
|
Local ready
Direct docking supported
|