| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L023421
BDB023421
|
BDBM534753
COC(=O)NC(CCCCC(=O)Nc1ccccc1N)C(=O)Nc1cccc(SC)c1
|
C22H28N4O4S 444.557000 |
DEJIMJVSLYSYRC-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534753; PubChem:CID139377866
|
Local ready
Direct docking supported
|
|
E3L023422
BDB023422
|
BDBM534757
CCC(=O)NC(CCCCC(=O)Nc1ccccc1N)C(=O)Nc1cccc(Br)c1
|
C22H27BrN4O3 475.387000 |
PILQVLXEOYXKCX-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534757; PubChem:CID139377787
|
Local ready
Direct docking supported
|
|
E3L023423
BDB023423
|
BDBM534760
Nc1ccccc1NC(=O)CCCCC(NC(=O)c1ccccc1)C(=O)Nc1cccc(Br)c1
|
C26H27BrN4O3 523.431000 |
CQNONIZTPBRONF-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534760; PubChem:CID139378012
|
Local ready
Direct docking supported
|
|
E3L023424
BDB023424
|
BDBM534761
Nc1ccccc1NC(=O)CCCCC(NC(=O)c1cccnc1)C(=O)Nc1cccc(Br)c1
|
C25H26BrN5O3 524.419000 |
PMQZMMHFCYYJBT-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534761; PubChem:CID139377811
|
Local ready
Direct docking supported
|
|
E3L023425
BDB023425
|
N'-(2-aminophenyl)-2-benzamido-N-phenylheptanediamide
Nc1ccccc1NC(=O)CCCCC(NC(=O)c1ccccc1)C(=O)Nc1ccccc1
|
C26H28N4O3 444.535000 |
OLJJLXQCZCJXKU-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534762; PubChem:CID139377818
|
Local ready
Direct docking supported
|
|
E3L023426
BDB023426
|
BDBM534770
COC(=O)NC(CCCCC(=O)Nc1ccccc1N)C(=O)Nc1cccc(OCC(F)(F)F)c1
|
C23H27F3N4O5 496.486000 |
AALOZFRGYDOUMN-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534770; PubChem:CID139377862
|
Local ready
Direct docking supported
|
|
E3L023427
BDB023427
|
BDBM534772
CCOC(=O)N[C@@H](CCCCC(=O)Nc1ccccc1N)C(=O)Nc1cccc(Br)c1
|
C22H27BrN4O4 491.386000 |
QLLJCTOWYSNMOY-IBGZPJMESA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534772; PubChem:CID139377820
|
Local ready
Direct docking supported
|
|
E3L023428
BDB023428
|
BDBM534784
COC(=O)NC(CCCCC(=O)Nc1ccccc1N)C(=O)Nc1nc(-c2ccncc2)cs1
|
C23H26N6O4S 482.566000 |
SVHJKKHZKNRAPY-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534784; PubChem:CID139378122
|
Local ready
Direct docking supported
|
|
E3L023429
BDB023429
|
BDBM534787
COC(=O)NC(CCCCC(=O)Nc1ccccc1N)C(=O)Nc1cccc2cccnc12
|
C24H27N5O4 449.511000 |
SZIUWBZVVUSRBT-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534787; PubChem:CID139377878
|
Local ready
Direct docking supported
|
|
E3L023430
BDB023430
|
BDBM534797
CCOC(=O)NC(CCCCC(=O)NCc1cncc(OCC)c1)C(=O)NCc1cncc(OCC)c1
|
C26H37N5O6 515.611000 |
YDDVJSUQAICRIP-UHFFFAOYSA-N | Q09472 | Histone acetyltransferase p300 |
BindingDB, PubChem
BindingDB:BDBM534797; PubChem:CID139377838
|
Local ready
Direct docking supported
|
|
E3L023431
BDB023431
|
US11236047, Example 8
CC(O)(CO)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C29H29Cl2NO5 542.459000 |
NVLQHQFGNPTQCC-ZBAATNBSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535132; PubChem:CID135281498
|
Local ready
Direct docking supported
|
|
E3L023432
BDB023432
|
US11236047, Example 10
COCC(C)(O)c1ccc2c(c1)C(=O)N([C@@H](C)c1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H33Cl2NO5 570.513000 |
UIFBZUZURMPJLE-VMDBBOCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535135; PubChem:CID135281724
|
Local ready
Direct docking supported
|
|
E3L023433
BDB023433
|
US11236047, Example 12
CN(C)CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H34Cl2N2O4 569.529000 |
FLSKRFKVCWLISS-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535138; PubChem:CID135281744
|
Local ready
Direct docking supported
|
|
E3L023434
BDB023434
|
US11236047, Example 19
CCC1(CO[C@]2(c3ccc(Cl)cc3)c3ccc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cc2)CC1
|
C30H31Cl2NO3 524.488000 |
ONXUOCISKNKLEO-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535154; PubChem:CID145765556
|
Local ready
Direct docking supported
|
|
E3L023435
BDB023435
|
US11236047, Example 22
C#Cc1ccc(CN2C(=O)c3cc(C(C)(O)CO)cc(F)c3[C@]2(OCC2(CO)CC2)c2ccc(Cl)cc2)cc1
|
C31H29ClFNO5 550.026000 |
LDOCNQIRVXHZQU-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535162; PubChem:CID135281420
|
Local ready
Direct docking supported
|
|
E3L023436
BDB023436
|
US11236047, Example 24
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H28ClFN2O4 535.015000 |
DIVMTXBUDOMYFO-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535163; PubChem:CID163407600
|
Local ready
Direct docking supported
|
|
E3L023437
BDB023437
|
US11236047, Example 37
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC1CCOC1)c1ccc(Cl)cc1
|
C28H27Cl2NO4 512.433000 |
ITVICYXWRBVNRA-GBAZGAGXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535193; PubChem:CID135281490
|
Local ready
Direct docking supported
|
|
E3L023438
BDB023438
|
US11236047, Example 39
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1CCOC1)c1ccc(Cl)cc1
|
C29H29Cl2NO4 526.460000 |
OTIYWWDOPCSJHZ-NORZDRCHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535196; PubChem:CID135281448
|
Local ready
Direct docking supported
|
|
E3L023439
BDB023439
|
US11236047, Example 41
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C34H36Cl2FNO7S 692.633000 |
JFGISRYCIHBUCK-SZFCLFMZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535204; PubChem:CID135281670
|
Local ready
Direct docking supported
|
|
E3L023440
BDB023440
|
US11236047, Example 43
CC(O)(CN1CCNCC1)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C34H38Cl2FN3O6S 706.664000 |
NTYHQRPYZXGTGT-SZFCLFMZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535205; PubChem:CID135281538
|
Local ready
Direct docking supported
|