| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L023441
BDB023441
|
US11236047, Example 46
C[C@@H](c1ccc(Cl)cc1)N1C(=O)c2cc(C(C)(C)O)ccc2[C@]1(O[C@@H]1COC[C@@H]1O)c1ccc(Cl)cc1
|
C29H29Cl2NO5 542.459000 |
JLJRDOGQKDSPHW-OPLXESSESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535207; PubChem:CID135281435
|
Local ready
Direct docking supported
|
|
E3L023442
BDB023442
|
US11236047, Example 56
CN(C)C(=O)C(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H32Cl2N2O5 583.512000 |
QSQWTXWPCPYZCQ-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535226; PubChem:CID135281506
|
Local ready
Direct docking supported
|
|
E3L023443
BDB023443
|
US11236047, Example 58
CNC(=O)C(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2N2O5 569.485000 |
FLAAYSHQWIAMDD-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535228; PubChem:CID135281484
|
Local ready
Direct docking supported
|
|
E3L023444
BDB023444
|
US11236047, Example 61
C[S+]([O-])c1cc(Cl)ccc1CN1C(=O)c2cc(C(C)(C)O)cc(F)c2[C@]1(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO5S 606.543000 |
PVRYETGYPNIACM-OKVUXXRHSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535231; PubChem:CID137405340
|
Local ready
Direct docking supported
|
|
E3L023445
BDB023445
|
US11236047, Example 63
COCC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C31H32Cl2FNO7S 652.568000 |
XPPOSVDBYKUPEU-ZGVDRVBQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535234; PubChem:CID135281521
|
Local ready
Direct docking supported
|
|
E3L023446
BDB023446
|
US11236047, Example 65
CC(O)(CO)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C30H30Cl2FNO7S 638.541000 |
HJVLHGXGDKFDKJ-FUJFQHJFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535235; PubChem:CID135281693
|
Local ready
Direct docking supported
|
|
E3L023447
BDB023447
|
US11236047, Example 67
CN1CCN(CC(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OC2CCOC2)c2ccc(Cl)cc2)CC1
|
C34H38Cl2FN3O6S 706.664000 |
GEZPZMXREXHEJZ-WRPALDRWSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535237; PubChem:CID154587067
|
Local ready
Direct docking supported
|
|
E3L023448
BDB023448
|
US11236047, Example 69
CN1CCN(CC(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(O[C@H]2CCOC2)c2ccc(Cl)cc2)CC1
|
C34H38Cl2FN3O6S 706.664000 |
GEZPZMXREXHEJZ-FNHRJEOVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535238; PubChem:CID135281717
|
Local ready
Direct docking supported
|
|
E3L023449
BDB023449
|
US11236047, Example 73
Cn1cc(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(C(N)=O)CC2)c2ccc(Cl)cc2)cn1
|
C33H31Cl2FN4O6S 701.604000 |
YLXVSCUQMYZKFT-NFCCVXSLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535242; PubChem:CID135281413
|
Local ready
Direct docking supported
|
|
E3L023450
BDB023450
|
US11236047, Example 81
CN1CCC(C(C)(O)c2cc(F)c3c(c2)C(=O)N(Cc2ccc(Cl)cc2S(C)(=O)=O)[C@@]3(OCC2(CO)CC2)c2ccc(Cl)cc2)CC1
|
C35H39Cl2FN2O6S 705.676000 |
MNUHQOFWGYDTKI-PWXSHKNQSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535247; PubChem:CID135281599
|
Local ready
Direct docking supported
|
|
E3L023451
BDB023451
|
US11236047, Example 83
CS(=O)(=O)c1cc(Cl)ccc1CN1C(=O)c2cc(C(O)C3CCOCC3)cc(F)c2[C@]1(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C33H34Cl2FNO7S 678.606000 |
IRIZYNABKNVLML-FULUQAKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535249; PubChem:CID135281613
|
Local ready
Direct docking supported
|
|
E3L023452
BDB023452
|
US11236047, Example 85
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1S(C)(=O)=O)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C34H35Cl2FN2O7S 705.632000 |
WPEIHYLRRFWOGP-SZFCLFMZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535250; PubChem:CID135281494
|
Local ready
Direct docking supported
|
|
E3L023453
BDB023453
|
US11236047, Example 88
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(O)C3CCOCC3)cc2C(=O)N1[C@@H](CC(=O)O)c1ccc(Cl)cc1
|
C31H30Cl2FNO6 602.486000 |
AVDHVIXZENQIRS-JCHZNZEOSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535251; PubChem:CID135281674
|
Local ready
Direct docking supported
|
|
E3L023454
BDB023454
|
US11236047, Example 96
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C33H30ClFN4O4 601.078000 |
CDUKUNZREUVQKN-UBORAUAPSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535254; PubChem:CID135281536
|
Local ready
Direct docking supported
|
|
E3L023455
BDB023455
|
US11236047, Example 98
CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(O)C3(F)CCOCC3)cc2C(=O)N1[C@@H](CC(=O)O)c1ccc(Cl)cc1
|
C31H29Cl2F2NO6 620.476000 |
HZTQINJSGAPBLS-SBYPTKLRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535255; PubChem:CID135281416
|
Local ready
Direct docking supported
|
|
E3L023456
BDB023456
|
US11236047, Example 101
CCC(O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1(F)CCOCC1
|
C32H31Cl2F2NO6 634.503000 |
HXHSKGLWTNIZIS-LTZUXFEUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535258; PubChem:CID135281540
|
Local ready
Direct docking supported
|
|
E3L023457
BDB023457
|
US11236047, Example 125
CCC(C)(O)c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(OCC1(F)COC1)c1ccc(Cl)cc1
|
C31H29Cl2F2NO6 620.476000 |
NAMQEWAUDBCILZ-SBYPTKLRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535261; PubChem:CID135281454
|
Local ready
Direct docking supported
|
|
E3L023458
BDB023458
|
US11236047, Example 127
CCC(O)(c1cc(F)c2c(c1)C(=O)N([C@@H](CC(=O)O)c1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)c1ccccn1
|
C32H27Cl2FN2O5 609.481000 |
KHSRSNYUTBONQS-LTZUXFEUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535262; PubChem:CID135281621
|
Local ready
Direct docking supported
|
|
E3L023459
BDB023459
|
US11236047, Example 137
CC[C@@](O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cc1)[C@@]2(OC)c1ccc(Cl)cc1)C1CCN(CCC(=O)O)CC1
|
C33H35Cl2FN2O5 629.556000 |
ZKUGFHUACFYRES-JHOUSYSJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535265; PubChem:CID135281444
|
Local ready
Direct docking supported
|
|
E3L023460
BDB023460
|
US11236047, Example 92
CCC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cc1CO)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1)c1cn(C)cn1
|
C34H32ClFN4O5 631.104000 |
LQLKHTDURGSYEY-FNHRJEOVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM535266; PubChem:CID135281612
|
Local ready
Direct docking supported
|