| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L026641
BDB026641
|
BDBM562090
Cc1nccc(-c2ccc(NC(=O)Cn3cnc4c3CCCC4)cc2)n1
|
C20H21N5O 347.422000 |
SIIAZODEFAHKEC-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562090; PubChem:CID134220625
|
Local ready
Direct docking supported
|
|
E3L026642
BDB026642
|
BDBM562091
O=C(Cn1cnc2c1CCCC2)Nc1ccc(-c2ccccc2F)nn1
|
C19H18FN5O 351.385000 |
MIAYYKNKFANYFX-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562091; PubChem:CID134220627
|
Local ready
Direct docking supported
|
|
E3L026643
BDB026643
|
BDBM562092
O=C(Cn1cnc2c1CCCC2)Nc1cnc(-c2ccccc2)nc1
|
C19H19N5O 333.395000 |
QCUUPUNWUCYNKA-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562092; PubChem:CID134220626
|
Local ready
Direct docking supported
|
|
E3L026644
BDB026644
|
BDBM562093
Cc1ccnc(-c2ccc(NC(=O)Cn3cnc4c3CCCC4)cc2)n1
|
C20H21N5O 347.422000 |
NRTMTQRPBULFAY-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562093; PubChem:CID134220628
|
Local ready
Direct docking supported
|
|
E3L026645
BDB026645
|
BDBM562094
Cc1cc(NC(=O)Cn2cnc3c2CCCC3)ccc1-c1ccncc1
|
C21H22N4O 346.434000 |
IVWCQXIYDWRILB-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562094; PubChem:CID134220629
|
Local ready
Direct docking supported
|
|
E3L026646
BDB026646
|
2-(2-phenylimidazol-1-yl)-N-(4-phenylphenyl)acetamide
O=C(Cn1ccnc1-c1ccccc1)Nc1ccc(-c2ccccc2)cc1
|
C23H19N3O 353.425000 |
COKJKNQMLICVBJ-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562095; PubChem:CID134220562
|
Local ready
Direct docking supported
|
|
E3L026647
BDB026647
|
2-imidazol-1-yl-N-(3-methyl-4-phenylphenyl)acetamide
Cc1cc(NC(=O)Cn2ccnc2)ccc1-c1ccccc1
|
C18H17N3O 291.354000 |
LUNCHPFRBQNLDB-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562096; PubChem:CID134220546
|
Local ready
Direct docking supported
|
|
E3L026648
BDB026648
|
BDBM562097
Cc1nc2c(c(N3CCCN(Cc4ccccc4)CC3)n1)CCCC2
|
C21H28N4 336.483000 |
DUPFHSJLAVGWMQ-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562097; PubChem:CID71858582
|
Local ready
Direct docking supported
|
|
E3L026649
BDB026649
|
BDBM562098
c1ccc(CN2CCCN(c3ncnc4c3CCCCC4)CC2)cc1
|
C21H28N4 336.483000 |
HPSROFOQHAQLCK-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562098; PubChem:CID134220547
|
Local ready
Direct docking supported
|
|
E3L026650
BDB026650
|
BDBM562099
c1ccc(CN2CCCN(c3ncnc4c3CCCC4)CC2)cc1
|
C20H26N4 322.456000 |
HNQVZHLYKDEKEM-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562099; PubChem:CID134220545
|
Local ready
Direct docking supported
|
|
E3L026651
BDB026651
|
BDBM562100
Cc1nc2c(c(N3CCCN(Cc4csc(C)n4)CC3)n1)CCCC2
|
C19H27N5S 357.527000 |
JIDHIJFFLUXFPU-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562100; PubChem:CID133460442
|
Local ready
Direct docking supported
|
|
E3L026652
BDB026652
|
BDBM562101
COc1ccc(CN2CCCN(c3ncnc4c3CN(C)CC4)CC2)cc1
|
C21H29N5O 367.497000 |
AXWZMIXISKDNKB-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562101; PubChem:CID134220649
|
Local ready
Direct docking supported
|
|
E3L026653
BDB026653
|
BDBM562102
Cc1nc2c(c(N3CCN(C(=O)c4ccccc4)CC3)n1)CCCC2
|
C20H24N4O 336.439000 |
NSNJHEKQMPTLLL-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562102; PubChem:CID134220651
|
Local ready
Direct docking supported
|
|
E3L026654
BDB026654
|
BDBM562103
Cc1nc2c(c(N3CCCN(Cc4noc(C5CC5)n4)CC3)n1)CCCC2
|
C20H28N6O 368.485000 |
WYVUQMYDPGJUJJ-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562103; PubChem:CID133460446
|
Local ready
Direct docking supported
|
|
E3L026655
BDB026655
|
BDBM562104
Cc1nc2c(c(N3CCCN(Cc4cccs4)CC3)n1)CCCC2
|
C19H26N4S 342.512000 |
CMPKQAXJLKRVGC-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562104; PubChem:CID138700698
|
Local ready
Direct docking supported
|
|
E3L026656
BDB026656
|
BDBM562105
Cc1nc2c(c(N3CCN(Cc4ccccc4)C(C)(C)C3)n1)CCCC2
|
C22H30N4 350.510000 |
FUAFXSZBWXBZCH-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562105; PubChem:CID138700699
|
Local ready
Direct docking supported
|
|
E3L026657
BDB026657
|
BDBM562106
Cc1nc2c(c(N3CCCN(Cc4ccc(Cl)cc4)CC3)n1)CCCC2
|
C21H27ClN4 370.928000 |
RERONISWSRWLKF-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562106; PubChem:CID138700701
|
Local ready
Direct docking supported
|
|
E3L026658
BDB026658
|
4-(4-Benzyl-1,4-diazepan-1-yl)pyrido[2,3-d]pyrimidine
c1ccc(CN2CCCN(c3ncnc4ncccc34)CC2)cc1
|
C19H21N5 319.412000 |
JJQQXJUZVUSDOE-UHFFFAOYSA-N | O60260 | E3 ubiquitin-protein ligase parkin |
BindingDB, PubChem
BindingDB:BDBM562107; PubChem:CID134220595
|
Local ready
Direct docking supported
|
|
E3L026659
BDB026659
|
US11401256, Example 2
CNC(=O)c1ccc2c(c1)nc(-c1cc(-c3cncn3C)nc3ccccc13)n2-c1ccc2c(c1)CCC(=O)N2
|
C31H25N7O2 527.588000 |
QXGJZPQVKZRAFS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562109; PubChem:CID137530761
|
Local ready
Direct docking supported
|
|
E3L026660
BDB026660
|
US11401256, Example 3
CCc1nc2cc(C(=O)NC)ccc2n1-c1ccc2c(c1)CCC(=O)N2
|
C20H20N4O2 348.406000 |
ODJADIRVHYABHQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562110; PubChem:CID137526021
|
Local ready
Direct docking supported
|