| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L026701
BDB026701
|
US11401256, Example 45
CNC(=O)c1ccc2c(c1)nc(-c1ccncc1C(F)(F)F)n2-c1ccc2c(c1)CCC(=O)N2
|
C24H18F3N5O2 465.435000 |
MEVQHOOPYAGAOO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562152; PubChem:CID137531986
|
Local ready
Direct docking supported
|
|
E3L026702
BDB026702
|
US11401256, Example 46
CNC(=O)c1ccc2c(c1)nc(-c1ccnc(CO)c1)n2-c1ccc2c(c1)CCC(=O)N2
|
C24H21N5O3 427.464000 |
PHKAXVHMPACGRX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562153; PubChem:CID137527167
|
Local ready
Direct docking supported
|
|
E3L026703
BDB026703
|
BDBM562155
CNC(=O)c1ccc2c(c1)nc(Cc1ccc(C(F)(F)F)cc1OC)n2-c1ccc2c(c1)CCC(=O)N2
|
C27H23F3N4O3 508.500000 |
TWSOGQZTXWOLLS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562155; PubChem:CID154591738
|
Local ready
Direct docking supported
|
|
E3L026704
BDB026704
|
US11401256, Example 48
CNC(=O)c1ccc2c(c1)nc(-c1cccnc1C(C)=O)n2-c1ccc2c(c1)CCC(=O)N2
|
C25H21N5O3 439.475000 |
CPIOFCOLTFRAOD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562156; PubChem:CID137525862
|
Local ready
Direct docking supported
|
|
E3L026705
BDB026705
|
US11401256, Example 49
CNC(=O)c1ccc2c(c1)nc(-c1ncccc1C(=O)NC)n2-c1ccc2c(c1)CCC(=O)N2
|
C25H22N6O3 454.490000 |
ZQKVRHIKYFFGHV-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562157; PubChem:CID137531991
|
Local ready
Direct docking supported
|
|
E3L026706
BDB026706
|
US11401256, Example 50
COC(=O)c1ccc2c(c1)nc(C(C)C)n2-c1ccc2c(n1)CCC(=O)N2
|
C20H20N4O3 364.405000 |
QKAXFRFMFSILBN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562158; PubChem:CID137526025
|
Local ready
Direct docking supported
|
|
E3L026707
BDB026707
|
US11401256, Example 51
CNC(=O)c1ccc2c(c1)nc(C(C)C)n2-c1ccc2c(n1)CCC(=O)N2
|
C20H21N5O2 363.421000 |
DENFGDXFDDVFQQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562159; PubChem:CID137526230
|
Local ready
Direct docking supported
|
|
E3L026708
BDB026708
|
US11401256, Example 52
CC(C)c1nc2cc(C(=O)N(C)C)ccc2n1-c1ccc2c(n1)CCC(=O)N2
|
C21H23N5O2 377.448000 |
IUWRBWSELXUPGP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562160; PubChem:CID137528162
|
Local ready
Direct docking supported
|
|
E3L026709
BDB026709
|
7-(1H-Imidazol-1-yl)-3,4-dihydroquinolin-2(1H)-one
O=C1CCc2ccc(-n3ccnc3)cc2N1
|
C12H11N3O 213.240000 |
HUMAFQTUANBPFL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562161; PubChem:CID137532048
|
Local ready
Direct docking supported
|
|
E3L026710
BDB026710
|
6-(Indoline-1-carbonyl)-3,4-dihydro-1H-quinolin-2-one
O=C1CCc2cc(C(=O)N3CCc4ccccc43)ccc2N1
|
C18H16N2O2 292.338000 |
ZYFYRNSAXIDKPY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562162; PubChem:CID18165382
|
Local ready
Direct docking supported
|
|
E3L026711
BDB026711
|
US11401256, Example 55
O=C1CCc2cc(C(=O)N3CCc4cccnc43)ccc2N1
|
C17H15N3O2 293.326000 |
KYWYVPXBCSEBHQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562163; PubChem:CID137527019
|
Local ready
Direct docking supported
|
|
E3L026712
BDB026712
|
US11401256, Example 56
O=C1CCc2cc(C(=O)N3CCCc4ccccc43)ccc2N1
|
C19H18N2O2 306.365000 |
HYKPFXYXAGCQSS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562164; PubChem:CID86911719
|
Local ready
Direct docking supported
|
|
E3L026713
BDB026713
|
US11401256, Example 57
CC(=O)N1CCC(NC(=O)c2ccc3c(c2)CCC(=O)N3)CC1
|
C17H21N3O3 315.373000 |
FDCHJBIIYHMVHG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562165; PubChem:CID137525871
|
Local ready
Direct docking supported
|
|
E3L026714
BDB026714
|
US11401256, Example 58
O=C1CCc2cc(C(=O)N3CCc4ccccc43)cnc2N1
|
C17H15N3O2 293.326000 |
WOOBFBFFSBDDCE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562166; PubChem:CID137532010
|
Local ready
Direct docking supported
|
|
E3L026715
BDB026715
|
US11401256, Example 59
O=C1CCc2cc(C(=O)N3CCc4cccnc43)cnc2N1
|
C16H14N4O2 294.314000 |
SOXCTXUWNIPELK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562167; PubChem:CID137525881
|
Local ready
Direct docking supported
|
|
E3L026716
BDB026716
|
US11401256, Example 60
O=C1CCc2cc(C(=O)N3CCCc4ccccc43)cnc2N1
|
C18H17N3O2 307.353000 |
FMQSIIABSLPCGC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562168; PubChem:CID137532080
|
Local ready
Direct docking supported
|
|
E3L026717
BDB026717
|
US11401256, Example 61
CC(C)c1nc2ccccc2n1-c1ccc2c(c1)CNC(=O)N2
|
C18H18N4O 306.369000 |
VQVQGEQVRYPDGR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562169; PubChem:CID137530778
|
Local ready
Direct docking supported
|
|
E3L026718
BDB026718
|
US11401256, Example 62
CNC(=O)c1ccc2c(c1)nc(C(C)C)n2-c1ccc2c(c1)CNC(=O)N2
|
C20H21N5O2 363.421000 |
BHRLXADKSSGUFR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562170; PubChem:CID147085144
|
Local ready
Direct docking supported
|
|
E3L026719
BDB026719
|
US11401256, Example A
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCCCCNC(=O)c1ccc3c(c1)nc(-c1cc(-c4cncn4C)nc4ccccc14)n3-c1ccc3c(c1)CCC(=O)N3)c1nnc(C)n1-2
|
C59H59ClN12O3S 1051.722000 |
ZDSKYEULGSPADI-GGCSAXROSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562171; PubChem:CID137532071
|
Local ready
Direct docking supported
|
|
E3L026720
BDB026720
|
US11401256, Example B
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCNC(=O)c1ccc3c(c1)nc(-c1cc(-c4cncn4C)nc4ccccc14)n3-c1ccc3c(c1)CCC(=O)N3)c1nnc(C)n1-2
|
C54H49ClN12O3S 981.587000 |
MUMOAWAISOWPKS-SJARJILFSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM562172; PubChem:CID148558298
|
Local ready
Direct docking supported
|