| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027221
BDB027221
|
US11420970, Example 36
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCC[C@](N)(COC2CCC2)C1
|
C27H31FN8O 502.598000 |
SVBVOSIPXYMSDS-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567835; PubChem:CID156073360
|
Local ready
Direct docking supported
|
|
E3L027222
BDB027222
|
US11420970, Example 37
CC(C)OC[C@@]1(N)CCCN(c2cnc(-c3ccc(F)cc3)cc2Cn2cnc3c(N)ncnc32)C1
|
C26H31FN8O 490.587000 |
LGRVOOPUVJMIJU-AREMUKBSSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567836; PubChem:CID156073419
|
Local ready
Direct docking supported
|
|
E3L027223
BDB027223
|
US11420970, Example 38
COC[C@@]1(N)CCCN(c2cnc(-c3ccc(OC)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C25H29FN8O2 492.559000 |
QPVMYPKWRAEDHU-RUZDIDTESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567837; PubChem:CID156073410
|
Local ready
Direct docking supported
|
|
E3L027224
BDB027224
|
US11420970, Example 39
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(COCC(F)(F)F)C3)cn2)cc1F
|
C26H28F4N8O2 560.556000 |
KOAUGJVUPXXRGB-RUZDIDTESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567838; PubChem:CID164850530
|
Local ready
Direct docking supported
|
|
E3L027225
BDB027225
|
US11420970, Example 40
Nc1ncnc2c1ncn2Cc1cc(-c2cccc(F)c2)ncc1N1CCC[C@](N)(COC(F)F)C1
|
C24H25F3N8O 498.513000 |
PMLLNTUYYIWNCY-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567839; PubChem:CID164850520
|
Local ready
Direct docking supported
|
|
E3L027226
BDB027226
|
US11420970, Example 41
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(COC(F)F)C1
|
C24H24F4N8O 516.503000 |
FJEAHBJMQCSDTB-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567840; PubChem:CID164850513
|
Local ready
Direct docking supported
|
|
E3L027227
BDB027227
|
US11420970, Example 42
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(COC(F)F)C3)cn2)cc1F
|
C25H27F3N8O2 528.539000 |
GVWOBXICSZKWHC-RUZDIDTESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567841; PubChem:CID164850515
|
Local ready
Direct docking supported
|
|
E3L027228
BDB027228
|
US11420970, Example 43
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(COCC(F)(F)F)C1
|
C25H25F5N8O 548.520000 |
FLUMCTPVAINAIP-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567842; PubChem:CID156073251
|
Local ready
Direct docking supported
|
|
E3L027229
BDB027229
|
US11420970, Example 44
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCC[C@](N)(COC(F)F)C1
|
C24H25F3N8O 498.513000 |
IDFFTZWPSDZFDP-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567843; PubChem:CID164850499
|
Local ready
Direct docking supported
|
|
E3L027230
BDB027230
|
US11420970, Example 45
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCC[C@](N)(COCC(F)(F)F)C1
|
C25H26F4N8O 530.530000 |
LIFQGKMVOWPGPO-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567844; PubChem:CID156073249
|
Local ready
Direct docking supported
|
|
E3L027231
BDB027231
|
US11420970, Example 47
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(CC(F)F)C1
|
C24H24F4N8 500.504000 |
KRAZUBZIXDBQMC-DEOSSOPVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567846; PubChem:CID156067105
|
Local ready
Direct docking supported
|
|
E3L027232
BDB027232
|
US11420970, Example 48
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(Cc2nccs2)C1
|
C26H25F2N9S 533.612000 |
QEMWURMVXDGLPX-SANMLTNESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567847; PubChem:CID156073407
|
Local ready
Direct docking supported
|
|
E3L027233
BDB027233
|
US11420970, Example 49
Cn1ccc(C[C@@]2(N)CCCN(c3cnc(-c4ccc(F)cc4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C27H29FN10 512.597000 |
IKLHFPLLTONFHI-MHZLTWQESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567848; PubChem:CID164850531
|
Local ready
Direct docking supported
|
|
E3L027234
BDB027234
|
US11420970, Example 50
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(Cc4ccccn4)C3)cn2)cc1F
|
C29H30FN9O 539.619000 |
FQVCXMNTGQQLSP-LJAQVGFWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567849; PubChem:CID164850549
|
Local ready
Direct docking supported
|
|
E3L027235
BDB027235
|
US11420970, Example 51
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(Cc2ccccn2)C1
|
C28H27F2N9 527.583000 |
PIAMYQASYPHGPD-NDEPHWFRSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567850; PubChem:CID156073230
|
Local ready
Direct docking supported
|
|
E3L027236
BDB027236
|
US11420970, Example 52
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(Cc2ncco2)C1
|
C26H25F2N9O 517.544000 |
FEVYCSQWSLZBQD-SANMLTNESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567851; PubChem:CID156073408
|
Local ready
Direct docking supported
|
|
E3L027237
BDB027237
|
US11420970, Example 55
Cc1cccc(C[C@@]2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C29H29F2N9 541.610000 |
XFEARXFCEJNXRF-LJAQVGFWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567854; PubChem:CID156073240
|
Local ready
Direct docking supported
|
|
E3L027238
BDB027238
|
US11420970, Example 56
Cn1ccc(C[C@@]2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C27H28F2N10 530.587000 |
BMSOFDFYSSYPMZ-MHZLTWQESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567855; PubChem:CID156073235
|
Local ready
Direct docking supported
|
|
E3L027239
BDB027239
|
US11420970, Example 57
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(Cc4nccs4)C3)cn2)cc1F
|
C27H28FN9OS 545.648000 |
UDPCSTXMWNKTFW-MHZLTWQESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567856; PubChem:CID164850555
|
Local ready
Direct docking supported
|
|
E3L027240
BDB027240
|
US11420970, Example 58
Nc1ncnc2c1ncn2Cc1cc(-c2cccc(F)c2)ncc1N1CCC[C@](N)(CC(=O)O)C1
|
C24H25FN8O2 476.516000 |
NODPKDWJJIWVKH-DEOSSOPVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567857; PubChem:CID156073236
|
Local ready
Direct docking supported
|