| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027281
BDB027281
|
US11420970, Example 100
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(C(=O)C2CCCC2)C1
|
C28H30F2N8O 532.599000 |
RIPPIFFFRACCJO-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567899; PubChem:CID156073417
|
Local ready
Direct docking supported
|
|
E3L027282
BDB027282
|
US11420970, Example 101
CC[C@H](C)C(=O)[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C27H30F2N8O 520.588000 |
GLJXHYDKIFHSPG-RKOGDMNLSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567900; PubChem:CID156073414
|
Local ready
Direct docking supported
|
|
E3L027283
BDB027283
|
US11420970, Example 102
CC[C@@H](C)C(=O)[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C27H30F2N8O 520.588000 |
GLJXHYDKIFHSPG-CHAGWJKLSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567901; PubChem:CID156073270
|
Local ready
Direct docking supported
|
|
E3L027284
BDB027284
|
US11420970, Example 103
CC(C(=O)C1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1)C1CC1
|
C28H30F2N8O 532.599000 |
SVRYUZROGWGLIK-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567902; PubChem:CID156073271
|
Local ready
Direct docking supported
|
|
E3L027285
BDB027285
|
US11420970, Example 104
CC(C)C(=O)[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C26H28F2N8O 506.561000 |
ZVSVORDAHTVADH-AREMUKBSSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567903; PubChem:CID156073268
|
Local ready
Direct docking supported
|
|
E3L027286
BDB027286
|
US11420970, Example 105
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(C(=O)C2CCC2)C1
|
C27H28F2N8O 518.572000 |
WWDGQXIVRMHWTR-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567904; PubChem:CID156073269
|
Local ready
Direct docking supported
|
|
E3L027287
BDB027287
|
US11420970, Example 106
COC1CCC(C(=O)C2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)C1
|
C29H32F2N8O2 562.625000 |
IUSMEXIBPDRIRT-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567905; PubChem:CID156073267
|
Local ready
Direct docking supported
|
|
E3L027288
BDB027288
|
US11420970, Example 107
CC1(C(=O)C2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)CC1
|
C27H28F2N8O 518.572000 |
CKULHZNFESQBFR-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567906; PubChem:CID156073309
|
Local ready
Direct docking supported
|
|
E3L027289
BDB027289
|
US11420970, Example 108
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(C(=O)C2CCOCC2)C1
|
C28H30F2N8O2 548.598000 |
NQBVQANNNPJVTI-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567907; PubChem:CID156073307
|
Local ready
Direct docking supported
|
|
E3L027290
BDB027290
|
US11420970, Example 109
CC(C)(C)C(=O)[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C27H30F2N8O 520.588000 |
KROSNWAAQJOKCL-HHHXNRCGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567908; PubChem:CID156073306
|
Local ready
Direct docking supported
|
|
E3L027291
BDB027291
|
US11420970, Example 110
Cn1ccc(C(=O)C2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)n1
|
C27H26F2N10O 544.570000 |
BCIHHNGJVXTFCG-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567909; PubChem:CID156073310
|
Local ready
Direct docking supported
|
|
E3L027292
BDB027292
|
US11420970, Example 111
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(C(=O)C2CCOC2)C1
|
C27H28F2N8O2 534.571000 |
GAJWTFREOMYAPO-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567910; PubChem:CID156073311
|
Local ready
Direct docking supported
|
|
E3L027293
BDB027293
|
US11420970, Example 112
CC1(C(=O)C2(N)CCCN(c3cnc(-c4ccc(F)c(F)c4)cc3Cn3cnc4c(N)ncnc43)C2)COC1
|
C27H28F2N8O2 534.571000 |
RVASZUDCQBMICF-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567911; PubChem:CID156073254
|
Local ready
Direct docking supported
|
|
E3L027294
BDB027294
|
US11420970, Example 113
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C24H24F4N8O 516.503000 |
DINCKUGYLLIMMO-GBXCKJPGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567912; PubChem:CID156070448
|
Local ready
Direct docking supported
|
|
E3L027295
BDB027295
|
US11420970, Example 114
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C24H24F4N8O 516.503000 |
DINCKUGYLLIMMO-HYBUGGRVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567913; PubChem:CID156067072
|
Local ready
Direct docking supported
|
|
E3L027296
BDB027296
|
US11420970, Example 115
Cc1cc(C(F)F)ccc1-c1cc(Cn2cnc3c(N)ncnc32)c(N2CCC[C@](N)([C@@H](O)C(F)F)C2)cn1
|
C26H28F4N8O 544.557000 |
LKOGIDSDIBCKAU-HFZDXXHNSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567914; PubChem:CID156073286
|
Local ready
Direct docking supported
|
|
E3L027297
BDB027297
|
US11420970, Example 116
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(OC(F)F)c(F)c2)ncc1N1CCC[C@](N)([C@H](O)C(F)F)C1
|
C25H25F5N8O2 564.519000 |
MWTXNOKOEWEHGS-CJFMBICVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567915; PubChem:CID156073287
|
Local ready
Direct docking supported
|
|
E3L027298
BDB027298
|
US11420970, Example 117
Cc1cc(F)c(F)cc1-c1cc(Cn2cnc3c(N)ncnc32)c(N2CCC[C@](N)([C@@H](O)C(F)F)C2)cn1
|
C25H26F4N8O 530.530000 |
OMGRTNUHVISOGJ-SQJMNOBHSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567916; PubChem:CID156073207
|
Local ready
Direct docking supported
|
|
E3L027299
BDB027299
|
US11420970, Example 118
COc1c(-c2ccc(F)c(F)c2)ncc(N2CCC[C@](N)([C@H](O)C(F)F)C2)c1Cn1cnc2c(N)ncnc21
|
C25H26F4N8O2 546.529000 |
OEIIGFMVVCOGPY-PXDATVDWSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567917; PubChem:CID156073208
|
Local ready
Direct docking supported
|
|
E3L027300
BDB027300
|
US11420970, Example 119
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(OC(F)F)c(F)c2)ncc1N1CCC[C@](N)([C@@H](O)C(F)F)C1
|
C25H25F5N8O2 564.519000 |
MWTXNOKOEWEHGS-NBGIEHNGSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567918; PubChem:CID156073217
|
Local ready
Direct docking supported
|