| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027241
BDB027241
|
US11420970, Example 59
Nc1ncnc2c1ncn2Cc1cc(-c2cccc(F)c2)ncc1N1CCC[C@@](N)(CC(=O)O)C1
|
C24H25FN8O2 476.516000 |
NODPKDWJJIWVKH-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567858; PubChem:CID165436679
|
Local ready
Direct docking supported
|
|
E3L027242
BDB027242
|
US11420970, Example 60
COCCC1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C25H28F2N8O 494.550000 |
UYGIDXNUVZZZBA-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567859; PubChem:CID156073237
|
Local ready
Direct docking supported
|
|
E3L027243
BDB027243
|
US11420970, Example 61
COc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCC[C@](N)(CC(F)F)C3)cn2)cc1F
|
C25H27F3N8O 512.540000 |
TYZNZYBELAQPML-VWLOTQADSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567860; PubChem:CID156073239
|
Local ready
Direct docking supported
|
|
E3L027244
BDB027244
|
US11420970, Example 62
NC(=O)C[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C24H25F2N9O 493.522000 |
PVWUQVPGOCUIOR-DEOSSOPVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567861; PubChem:CID156073232
|
Local ready
Direct docking supported
|
|
E3L027245
BDB027245
|
US11420970, Example 64
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(NC(=O)CCBr)cc2)ncc1N1CCCC(N)(CC(F)F)C1
|
C27H30BrF2N9O 614.499000 |
DVGCCCHBLUDPJV-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567863; PubChem:CID156073228
|
Local ready
Direct docking supported
|
|
E3L027246
BDB027246
|
US11420970, Example 65
C[C@@H](c1ccccn1)[C@@]1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C29H29F2N9 541.610000 |
VRNWBFKTNPORKJ-RBSBEOHCSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567864; PubChem:CID156073234
|
Local ready
Direct docking supported
|
|
E3L027247
BDB027247
|
US11420970, Example 66
CNC(=O)CC1(N)CCCN(c2cnc(-c3cccc(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C25H28FN9O 489.559000 |
SMCAYNPMBWUAFL-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567865; PubChem:CID164850511
|
Local ready
Direct docking supported
|
|
E3L027248
BDB027248
|
US11420970, Example 67
CNC(=O)CC1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncc(Cl)c32)C1
|
C26H27ClF2N8O 541.006000 |
CAJNXZFOFSGLQO-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567866; PubChem:CID156073264
|
Local ready
Direct docking supported
|
|
E3L027249
BDB027249
|
US11420970, Example 68
CN(C)C(=O)CC1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C26H29F2N9O 521.576000 |
WKRXTRNHYJIKSK-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567867; PubChem:CID164850546
|
Local ready
Direct docking supported
|
|
E3L027250
BDB027250
|
US11420970, Example 69
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCCC(N)(Cc2cccc(F)n2)C1
|
C28H26F3N9 545.573000 |
SPRGFVQMVFFNBI-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567868; PubChem:CID156073260
|
Local ready
Direct docking supported
|
|
E3L027251
BDB027251
|
US11420970, Example 70
CN(C)C(=O)C[C@@]1(N)CCCN(c2cnc(-c3cccc(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C26H30FN9O 503.586000 |
MMJIJQPNVAOZLE-SANMLTNESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567869; PubChem:CID156073259
|
Local ready
Direct docking supported
|
|
E3L027252
BDB027252
|
US11420970, Example 71
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)cc2)ncc1N1CCC[C@](N)(CC(F)F)C1
|
C24H25F3N8 482.514000 |
FMDLHNNUSXWWIR-DEOSSOPVSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567870; PubChem:CID156073263
|
Local ready
Direct docking supported
|
|
E3L027253
BDB027253
|
US11420970, Example 72
CNC(=O)CC1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C25H27F2N9O 507.549000 |
NECVTPJOXKGTGK-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567871; PubChem:CID164850508
|
Local ready
Direct docking supported
|
|
E3L027254
BDB027254
|
US11420970, Example 73
COC(=O)C[C@@]1(N)CCCN(c2cnc(-c3cccc(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C25H27FN8O2 490.543000 |
ASGCHPPYHXTBIP-VWLOTQADSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567872; PubChem:CID156073245
|
Local ready
Direct docking supported
|
|
E3L027255
BDB027255
|
US11420970, Example 74
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(F)c(F)c2)ncc1N1CCC[C@](N)(Cc2cnccn2)C1
|
C27H26F2N10 528.571000 |
OVYYRMJWPLGNME-MHZLTWQESA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567873; PubChem:CID156073238
|
Local ready
Direct docking supported
|
|
E3L027256
BDB027256
|
US11420970, Example 75
Nc1ncnc2c1ncn2Cc1cc(-c2ccc(CNC(=O)CCl)cc2)ncc1N1CCCC(N)(CC(F)F)C1
|
C27H30ClF2N9O 570.048000 |
LCIMLMNEEAARMS-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567874; PubChem:CID156073242
|
Local ready
Direct docking supported
|
|
E3L027257
BDB027257
|
US11420970, Example 76
C=CC(=O)Nc1ccc(-c2cc(Cn3cnc4c(N)ncnc43)c(N3CCCC(N)(CC(F)F)C3)cn2)cc1
|
C27H29F2N9O 533.587000 |
VWKPXHQRVOWUMG-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567875; PubChem:CID156073243
|
Local ready
Direct docking supported
|
|
E3L027258
BDB027258
|
US11420970, Example 77
N#CCC1(N)CCCN(c2cnc(-c3ccc(F)c(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C24H23F2N9 475.507000 |
AKAGOZYDVDBEDJ-UHFFFAOYSA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567876; PubChem:CID156073159
|
Local ready
Direct docking supported
|
|
E3L027259
BDB027259
|
US11420970, Example 78
CNC(=O)[C@@]1(N)CCCN(c2cnc(-c3cccc(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C24H26FN9O 475.532000 |
IPRSLMKMBHEPBF-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567877; PubChem:CID156067074
|
Local ready
Direct docking supported
|
|
E3L027260
BDB027260
|
US11420970, Example 79
COC(=O)[C@@]1(N)CCCN(c2cnc(-c3cccc(F)c3)cc2Cn2cnc3c(N)ncnc32)C1
|
C24H25FN8O2 476.516000 |
HKASRBNRUOHOGB-XMMPIXPASA-N | O96028 | Histone-lysine N-methyltransferase NSD2 |
BindingDB, PubChem
BindingDB:BDBM567878; PubChem:CID164850501
|
Local ready
Direct docking supported
|