| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027601
BDB027601
|
US11458138, Example 4
CC(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C15H12F3N5 319.290000 |
PTTKHXBEPPAXSE-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM573884; PubChem:CID135390260
|
Local ready
Direct docking supported
|
|
E3L027602
BDB027602
|
US11458138, Example 5
CC(C)N(C)c1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5 279.347000 |
WIUJMTVJKOGUKW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM573889; PubChem:CID135368488
|
Local ready
Direct docking supported
|
|
E3L027603
BDB027603
|
US11458138, Example 6
CC(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C15H15N5 265.320000 |
JDMAQIORUXZAGZ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM573896; PubChem:CID135368310
|
Local ready
Direct docking supported
|
|
E3L027604
BDB027604
|
US11458138, Example 7
COCC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5O 309.373000 |
JJNZJRXOAFOQOK-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM573900; PubChem:CID145744584
|
Local ready
Direct docking supported
|
|
E3L027605
BDB027605
|
US11458138, Example 8
COCCC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H21N5O 323.400000 |
IKOCQBSJIXAKFW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574172; PubChem:CID135368054
|
Local ready
Direct docking supported
|
|
E3L027606
BDB027606
|
US11458138, Example 9
CCCCN(C)c1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5 293.374000 |
LVLQXXQGVYAPPD-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574173; PubChem:CID145744615
|
Local ready
Direct docking supported
|
|
E3L027607
BDB027607
|
US11458138, Example 10
CCN(C)c1nc(-c2ccncc2)nc2cnccc12
|
C15H15N5 265.320000 |
IAVUROGJBRGFQM-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574174; PubChem:CID135368374
|
Local ready
Direct docking supported
|
|
E3L027608
BDB027608
|
US11458138, Example 11
CC(C)(COCCO)Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H21N5O2 339.399000 |
JVCDXTHYVYGMQC-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574175; PubChem:CID135368398
|
Local ready
Direct docking supported
|
|
E3L027609
BDB027609
|
US11458138, Example 12
CC(C)(O)COCC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C20H25N5O2 367.453000 |
TWSFYAXEDIOFFN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574176; PubChem:CID135368578
|
Local ready
Direct docking supported
|
|
E3L027610
BDB027610
|
US11458138, Example 13
CCNc1nc(-c2ccncc2)nc2cnccc12
|
C14H13N5 251.293000 |
GQGWDQHPZWUVSN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574177; PubChem:CID135368671
|
Local ready
Direct docking supported
|
|
E3L027611
BDB027611
|
US11458138, Example 14
CCCNc1nc(-c2ccncc2)nc2cnccc12
|
C15H15N5 265.320000 |
WKYHVIILYCJVBF-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574178; PubChem:CID135368629
|
Local ready
Direct docking supported
|
|
E3L027612
BDB027612
|
US11458138, Example 15
CC(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C1CCCCC1
|
C21H25N5 347.466000 |
UCTAUHCKGLOZHU-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574179; PubChem:CID135390227
|
Local ready
Direct docking supported
|
|
E3L027613
BDB027613
|
US11458138, Example 16
CC1(Nc2nc(-c3ccncc3)nc3cnccc23)COC1
|
C16H15N5O 293.330000 |
LCYSQYUKFGGZIW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574180; PubChem:CID135368318
|
Local ready
Direct docking supported
|
|
E3L027614
BDB027614
|
US11458138, Example 17a
CC1CCCC1Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H19N5 305.385000 |
WIFZIPRZHKCGGL-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574181; PubChem:CID135368339
|
Local ready
Direct docking supported
|
|
E3L027615
BDB027615
|
US11458138, Example 17b
C[C@H]1CCC[C@H]1Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H19N5 305.385000 |
WIFZIPRZHKCGGL-SWLSCSKDSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574183; PubChem:CID135368041
|
Local ready
Direct docking supported
|
|
E3L027616
BDB027616
|
US11458138, Example 18
CC(O)C(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5O 309.373000 |
IPIGEINTEQDZHN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574186; PubChem:CID145744563
|
Local ready
Direct docking supported
|
|
E3L027617
BDB027617
|
US11458138, Example 19
CCCCNc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5 279.347000 |
DWHXKVQKWCEQJZ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574187; PubChem:CID145744602
|
Local ready
Direct docking supported
|
|
E3L027618
BDB027618
|
US11458138, Example 20
CC(C)(CCc1ccccc1)Nc1nc(-c2ccncc2)nc2cnccc12
|
C23H23N5 369.472000 |
TZQPUNBWPSZOOO-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574188; PubChem:CID145744579
|
Local ready
Direct docking supported
|
|
E3L027619
BDB027619
|
US11458138, Example 21
c1cc(-c2nc(NC3CC3)c3ccncc3n2)ccn1
|
C15H13N5 263.304000 |
GKVHLEFLVJTNPO-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574189; PubChem:CID145744587
|
Local ready
Direct docking supported
|
|
E3L027620
BDB027620
|
US11458138, Example 22
CC(C)(CCS(C)(=O)=O)Nc1nc(-c2ccncc2)nc2cnccc12
|
C18H21N5O2S 371.466000 |
QDAKMSNBCYZPNH-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574190; PubChem:CID145744557
|
Local ready
Direct docking supported
|