| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027621
BDB027621
|
US11458138, Example 23
CC(CO)(CO)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5O2 311.345000 |
GASZFPAPBAGRFK-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574191; PubChem:CID135368383
|
Local ready
Direct docking supported
|
|
E3L027622
BDB027622
|
US11458138, Example 24
CC(O)C(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5O 295.346000 |
DIENBOUAPGFURA-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574192; PubChem:CID145744603
|
Local ready
Direct docking supported
|
|
E3L027623
BDB027623
|
US11458138, Example 25
CC(C)(COCC(=O)OC(C)(C)C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C22H27N5O3 409.490000 |
UZGBSTWNDVJUQY-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574193; PubChem:CID145744577
|
Local ready
Direct docking supported
|
|
E3L027624
BDB027624
|
US11458138, Example 26
O[C@@H]1CCC[C@@H]1Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H17N5O 307.357000 |
KLRVBQBFDCULDA-DZGCQCFKSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574194; PubChem:CID135368496
|
Local ready
Direct docking supported
|
|
E3L027625
BDB027625
|
US11458138, Example 27
OCCC(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C16H14F3N5O 349.316000 |
IAZHZBCGXPBBTK-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574195; PubChem:CID145744585
|
Local ready
Direct docking supported
|
|
E3L027626
BDB027626
|
US11458138, Example 28
CC(C)(CS(C)(=O)=O)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5O2S 357.439000 |
POQZSRVIOIFGKW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574196; PubChem:CID145744620
|
Local ready
Direct docking supported
|
|
E3L027627
BDB027627
|
US11458138, Example 29
C[C@](Nc1nc(-c2ccncc2)nc2cnccc12)(C(=O)O)C(F)(F)F
|
C16H12F3N5O2 363.299000 |
PYEVQSJFZMQBQW-HNNXBMFYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574197; PubChem:CID135368368
|
Local ready
Direct docking supported
|
|
E3L027628
BDB027628
|
US11458138, Example 30
CC(C)(CNCC(=O)OC(C)(C)C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C22H28N6O2 408.506000 |
WXNKYOKEXMAFRY-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574198; PubChem:CID135368334
|
Local ready
Direct docking supported
|
|
E3L027629
BDB027629
|
US11458138, Example 31
C[C@@](Nc1nc(-c2ccncc2)nc2cnccc12)(C(=O)O)C(F)(F)F
|
C16H12F3N5O2 363.299000 |
PYEVQSJFZMQBQW-OAHLLOKOSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574199; PubChem:CID135368543
|
Local ready
Direct docking supported
|
|
E3L027630
BDB027630
|
US11458138, Example 32
COC(=O)C(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H17N5O2 323.356000 |
RRSMFGFPCJAXDS-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574200; PubChem:CID135368337
|
Local ready
Direct docking supported
|
|
E3L027631
BDB027631
|
US11458138, Example 33
O[C@H]1CCC[C@@H]1Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H17N5O 307.357000 |
KLRVBQBFDCULDA-ZFWWWQNUSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574201; PubChem:CID137350642
|
Local ready
Direct docking supported
|
|
E3L027632
BDB027632
|
US11458138, Example 34
CC(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C(=O)O
|
C16H15N5O2 309.329000 |
OQRUYEZIKILWAN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574202; PubChem:CID145744589
|
Local ready
Direct docking supported
|
|
E3L027633
BDB027633
|
US11458138, Example 35
OCCOCCNc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5O2 311.345000 |
MELBXLWGBVOQKW-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574203; PubChem:CID145744592
|
Local ready
Direct docking supported
|
|
E3L027634
BDB027634
|
US11458138, Example 36
OCC(CO)(CO)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5O3 327.344000 |
ZOBZTNONBIVPBE-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574204; PubChem:CID135390582
|
Local ready
Direct docking supported
|
|
E3L027635
BDB027635
|
US11458138, Example 37
CC(C)(CC(=O)O)NC(=O)CC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C22H26N6O3 422.489000 |
WCQPMDZTXCNBCS-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574205; PubChem:CID135368319
|
Local ready
Direct docking supported
|
|
E3L027636
BDB027636
|
US11458138, Example 38
FC(F)(F)C(Cc1ccccc1)Nc1nc(-c2ccncc2)nc2cnccc12
|
C21H16F3N5 395.388000 |
RZKZFFWUWPPNTB-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574206; PubChem:CID135390228
|
Local ready
Direct docking supported
|
|
E3L027637
BDB027637
|
US11458138, Example 39
CN(C)C1(CNc2nc(-c3ccncc3)nc3cnccc23)CCOCC1
|
C20H24N6O 364.453000 |
HIYCWXLYNZFJAZ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574207; PubChem:CID135368686
|
Local ready
Direct docking supported
|
|
E3L027638
BDB027638
|
US11458138, Example 40
CC(C)(CC(=O)O)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H17N5O2 323.356000 |
WGVSTJVCGGERPS-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574208; PubChem:CID145744622
|
Local ready
Direct docking supported
|
|
E3L027639
BDB027639
|
US11458138, Example 41
CS(=O)(=O)CCNc1nc(-c2ccncc2)nc2cnccc12
|
C15H15N5O2S 329.385000 |
JMKUYEUELMQPJK-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574209; PubChem:CID135368573
|
Local ready
Direct docking supported
|
|
E3L027640
BDB027640
|
US11458138, Example 42
CC(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C12CC3CC(CC(C3)C1)C2
|
C25H29N5 399.542000 |
FHIDYUVEUBDRGZ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574210; PubChem:CID145744621
|
Local ready
Direct docking supported
|