| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L027641
BDB027641
|
US11458138, Example 43
CC(C)C(=O)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H15N5O 293.330000 |
KCEUCVPLQWZOKO-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574211; PubChem:CID145744553
|
Local ready
Direct docking supported
|
|
E3L027642
BDB027642
|
US11458138, Example 44
O=C(O)CC(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C16H12F3N5O2 363.299000 |
QFNNCKXRUFCTPO-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574212; PubChem:CID135368702
|
Local ready
Direct docking supported
|
|
E3L027643
BDB027643
|
US11458138, Example 45
CC(C)S(=O)(=O)Nc1nc(-c2ccncc2)nc2cnccc12
|
C15H15N5O2S 329.385000 |
UNFWVNMNQRHTOQ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574213; PubChem:CID145744598
|
Local ready
Direct docking supported
|
|
E3L027644
BDB027644
|
US11458138, Example 46
c1cc(-c2nc(NCCCc3nnn[nH]3)c3ccncc3n2)ccn1
|
C16H15N9 333.359000 |
GSYJHCKYYPELPH-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574214; PubChem:CID135368713
|
Local ready
Direct docking supported
|
|
E3L027645
BDB027645
|
US11458138, Example 47
CC(N(C)c1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C16H14F3N5 333.317000 |
SBPQHDLJGZBWTL-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574215; PubChem:CID135368289
|
Local ready
Direct docking supported
|
|
E3L027646
BDB027646
|
US11458138, Example 48a
C[C@H](N(C)c1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C16H14F3N5 333.317000 |
SBPQHDLJGZBWTL-JTQLQIEISA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574216; PubChem:CID135368493
|
Local ready
Direct docking supported
|
|
E3L027647
BDB027647
|
US11458138, Example 48b
C[C@@H](N(C)c1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C16H14F3N5 333.317000 |
SBPQHDLJGZBWTL-SNVBAGLBSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574217; PubChem:CID135368404
|
Local ready
Direct docking supported
|
|
E3L027648
BDB027648
|
US11458138, Example 49
CC(C)(O)CC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C19H23N5O 337.427000 |
RQCQSMAAAMSVHQ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574218; PubChem:CID135368532
|
Local ready
Direct docking supported
|
|
E3L027649
BDB027649
|
US11458138, Example 50
CC(C)(O)C(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C18H18F3N5O 377.370000 |
GSVWCAAXRHTWGQ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574219; PubChem:CID145744565
|
Local ready
Direct docking supported
|
|
E3L027650
BDB027650
|
US11458138, Example 51
OCC1(Nc2nc(-c3ccncc3)nc3cnccc23)CCCC1
|
C18H19N5O 321.384000 |
SVGULJTZHBJDQN-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574220; PubChem:CID145744595
|
Local ready
Direct docking supported
|
|
E3L027651
BDB027651
|
US11458138, Example 52
COC1CC(Nc2nc(-c3ccncc3)nc3cnccc23)C1
|
C17H17N5O 307.357000 |
HGHQVNSLNJYMGG-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574221; PubChem:CID145744552
|
Local ready
Direct docking supported
|
|
E3L027652
BDB027652
|
US11458138, Example 53
CN[C@@H]1CCCC[C@H]1N(C)c1nc(-c2ccncc2)nc2cnccc12
|
C20H24N6 348.454000 |
MSMNYSIKXYTNCQ-SJLPKXTDSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574222; PubChem:CID135368053
|
Local ready
Direct docking supported
|
|
E3L027653
BDB027653
|
BDBM574223
COC(=O)[C@H]1C[C@@H](Nc2nc(-c3ccncc3)nc3cnccc23)C1
|
C18H17N5O2 335.367000 |
FKNHFSIQSCWSDP-BETUJISGSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB
BindingDB:BDBM574223
|
Local ready
Direct docking supported
|
|
E3L027654
BDB027654
|
US11458138, Example 55
CCOC(=O)C1(Nc2nc(-c3ccncc3)nc3cnccc23)CCC1
|
C19H19N5O2 349.394000 |
OSIDZXHCCXCWJQ-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574224; PubChem:CID135368013
|
Local ready
Direct docking supported
|
|
E3L027655
BDB027655
|
US11458138, Example 56
O=C(O)C1(Nc2nc(-c3ccncc3)nc3cnccc23)CCC1
|
C17H15N5O2 321.340000 |
SSJDFYPBHPQTFR-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574225; PubChem:CID145744580
|
Local ready
Direct docking supported
|
|
E3L027656
BDB027656
|
US11458138, Example 57
O=C(O)C1CC(Nc2nc(-c3ccncc3)nc3cnccc23)C1
|
C17H15N5O2 321.340000 |
VRFJYJCNSQZKIM-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574226; PubChem:CID135368290
|
Local ready
Direct docking supported
|
|
E3L027657
BDB027657
|
US11458138, Example 58
CC(C)(Nc1nc(-c2ccncc2)nc2cnccc12)C(F)(F)F
|
C16H14F3N5 333.317000 |
VJFDDNKVWALCBK-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574227; PubChem:CID137350931
|
Local ready
Direct docking supported
|
|
E3L027658
BDB027658
|
US11458138, Example 59
CC(C)(C)Nc1nc(-c2ccncc2)nc2cnccc12
|
C16H17N5 279.347000 |
AFJHACZNTJKCIF-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574228; PubChem:CID145744614
|
Local ready
Direct docking supported
|
|
E3L027659
BDB027659
|
US11458138, Example 60
CC1(Nc2nc(-c3ccncc3)nc3cnccc23)CCC1
|
C17H17N5 291.358000 |
KWOCVIVWJGXOCX-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574229; PubChem:CID145744612
|
Local ready
Direct docking supported
|
|
E3L027660
BDB027660
|
US11458138, Example 61
CC(C)(CCO)Nc1nc(-c2ccncc2)nc2cnccc12
|
C17H19N5O 309.373000 |
YXFRTVUVQNPAHF-UHFFFAOYSA-N | O95835 | Serine/threonine-protein kinase LATS1 |
BindingDB, PubChem
BindingDB:BDBM574230; PubChem:CID135368356
|
Local ready
Direct docking supported
|