| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L029441
BDB029441
|
BDBM588373
[N-]=[N+]=NCCOCCOCCOCCNc1cc(-c2ccc3c(c2)CC(=O)N3)ccn1
|
C21H26N6O4 426.477000 |
FVUDMDPUJAHYRY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588373; PubChem:CID156194246
|
Local ready
Direct docking supported
|
|
E3L029442
BDB029442
|
BDBM588374
[N-]=[N+]=NCCOCCOCCOCCNc1ccc(-c2ccc3c(c2)NC(=O)C3)cn1
|
C21H26N6O4 426.477000 |
OCCGCCIKXAAJQJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588374; PubChem:CID156194220
|
Local ready
Direct docking supported
|
|
E3L029443
BDB029443
|
BDBM588375
Nc1ccc(OCCOCCOCCOCCNC(=O)c2cccc(-c3ccc4c(c3)NC(=O)C4)c2)cc1
|
C29H33N3O6 519.598000 |
MEMCAIAUHRTPHZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588375; PubChem:CID156194205
|
Local ready
Direct docking supported
|
|
E3L029444
BDB029444
|
BDBM588376
Nc1ccc(OCCOCCOCCOCCNC(=O)c2cccc(-c3ccc4c(c3)CC(=O)N4)c2)cc1
|
C29H33N3O6 519.598000 |
ZJMSFBXBDJHMQY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588376; PubChem:CID156194234
|
Local ready
Direct docking supported
|
|
E3L029445
BDB029445
|
BDBM588377
[N-]=[N+]=NCCOCCOCCOCCNc1ccc(-c2ccc3c(c2)CC(=O)N3)cn1
|
C21H26N6O4 426.477000 |
PITAYWBGJNAZST-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588377; PubChem:CID156194194
|
Local ready
Direct docking supported
|
|
E3L029446
BDB029446
|
BDBM588378
Nc1ccc(OCCOCCOCCOCCNc2ccc(-c3ccc4c(c3)CC(=O)N4)cn2)cc1
|
C27H32N4O5 492.576000 |
KGRQMODPGBTHBG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588378; PubChem:CID156194140
|
Local ready
Direct docking supported
|
|
E3L029447
BDB029447
|
BDBM588379
[N-]=[N+]=NCCOCCOCCOCCNc1ncccc1-c1ccc2c(c1)CC(=O)N2
|
C21H26N6O4 426.477000 |
ORVQYBPYGAKXAA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588379; PubChem:CID156194210
|
Local ready
Direct docking supported
|
|
E3L029448
BDB029448
|
BDBM588380
[N-]=[N+]=NCCOCCOCCOCCNc1ncccc1-c1ccc2c(c1)NC(=O)C2
|
C21H26N6O4 426.477000 |
VUBDUANPFWNSNJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM588380; PubChem:CID156194218
|
Local ready
Direct docking supported
|
|
E3L029449
BDB029449
|
4-Cyano-2-(2-fluoro-4-iodoanilino)benzoic acid
N#Cc1ccc(C(=O)O)c(Nc2ccc(I)cc2F)c1
|
C14H8FIN2O2 382.132000 |
LMHQOKIYCWPJDJ-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592177; PubChem:CID148370986
|
Local ready
Direct docking supported
|
|
E3L029450
BDB029450
|
US11572344, Example 7
CONC(=O)c1ccc(C#N)cc1Nc1ccc(I)cc1F
|
C15H11FIN3O2 411.174000 |
PXZPYLSQABQCQU-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592179; PubChem:CID148992621
|
Local ready
Direct docking supported
|
|
E3L029451
BDB029451
|
US11572344, Example 8
CCONC(=O)c1ccc(C#N)cc1Nc1ccc(I)cc1F
|
C16H13FIN3O2 425.201000 |
DTSPZGBVICRZHG-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592180; PubChem:CID147427744
|
Local ready
Direct docking supported
|
|
E3L029452
BDB029452
|
US11572344, Example 9
CCCONC(=O)c1ccc(C#N)cc1Nc1ccc(I)cc1F
|
C17H15FIN3O2 439.228000 |
BNNRCTRNLFAQLK-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592181; PubChem:CID153593304
|
Local ready
Direct docking supported
|
|
E3L029453
BDB029453
|
US11572344, Example 10
N#Cc1ccc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c1
|
C16H13FIN3O3 441.200000 |
XVGJVNTVXWUAOJ-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592182; PubChem:CID153593279
|
Local ready
Direct docking supported
|
|
E3L029454
BDB029454
|
US11572344, Example 11
Cc1cc(I)ccc1Nc1cc(C#N)ccc1C(=O)NOCCO
|
C17H16IN3O3 437.237000 |
JJVMFDVNVXAYKA-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592183; PubChem:CID162695008
|
Local ready
Direct docking supported
|
|
E3L029455
BDB029455
|
US11572344, Example 12
N#Cc1ccc(C(=O)NOCC2CC2)c(Nc2ccc(I)cc2F)c1
|
C18H15FIN3O2 451.239000 |
OJGXFEANLCFNGI-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592184; PubChem:CID153593410
|
Local ready
Direct docking supported
|
|
E3L029456
BDB029456
|
US11572344, Example 13
Cc1cc(I)ccc1Nc1cc(C#N)ccc1C(=O)NOCC1CC1
|
C19H18IN3O2 447.276000 |
ROROXAPQIFBIFG-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592185; PubChem:CID153593370
|
Local ready
Direct docking supported
|
|
E3L029457
BDB029457
|
4-cyano-2-(2-fluoro-4-iodoanilino)-N-hydroxybenzamide
N#Cc1ccc(C(=O)NO)c(Nc2ccc(I)cc2F)c1
|
C14H9FIN3O2 397.147000 |
YNXBMXIQNAXTJJ-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592186; PubChem:CID153593305
|
Local ready
Direct docking supported
|
|
E3L029458
BDB029458
|
BDBM592187
N#Cc1ccc(C(=O)NOCCN)c(Nc2ccc(I)cc2F)c1
|
C16H14FIN4O2 440.216000 |
RSEILXINXSTMSN-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592187; PubChem:CID151768901
|
Local ready
Direct docking supported
|
|
E3L029459
BDB029459
|
BDBM592188
COC(=O)CCONC(=O)c1ccc(C#N)cc1Nc1ccc(I)cc1F
|
C18H15FIN3O4 483.237000 |
NTCIIIMOVZCMOX-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592188; PubChem:CID153593186
|
Local ready
Direct docking supported
|
|
E3L029460
BDB029460
|
BDBM592189
N#Cc1ccc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c1F
|
C16H12F2IN3O3 459.190000 |
HTTSGPZJJGCPGR-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592189; PubChem:CID162351014
|
Local ready
Direct docking supported
|