| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L029481
BDB029481
|
US11584748, Example 20
O=C1CCC2(CCN(c3nc4cnccc4s3)C2)C(=O)N1
|
C14H14N4O2S 302.359000 |
AENLBVHUZYBTFQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594653; PubChem:CID146198240
|
Local ready
Direct docking supported
|
|
E3L029482
BDB029482
|
US11584748, Example 21
COC(=O)c1ccc2nc(N3CCC4(CCC(=O)NC4=O)C3)sc2c1
|
C17H17N3O4S 359.407000 |
UQAFBLUNEWMEHB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594654; PubChem:CID146198278
|
Local ready
Direct docking supported
|
|
E3L029483
BDB029483
|
US11584748, Example 22
COC(=O)c1csc(N2CCC3(CCC(=O)NC3=O)C2)n1
|
C13H15N3O4S 309.347000 |
VKABBEPIOBLFPO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594655; PubChem:CID146198244
|
Local ready
Direct docking supported
|
|
E3L029484
BDB029484
|
US11584748, Example 23
COC(=O)c1cnc(N2CCC3(CCC(=O)NC3=O)C2)s1
|
C13H15N3O4S 309.347000 |
KQOZMPLYKDKZDJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594656; PubChem:CID146198288
|
Local ready
Direct docking supported
|
|
E3L029485
BDB029485
|
US11584748, Example 24
CC(C)(C)OC(=O)c1ccc(N2CCC3(CCC(=O)NC3=O)C2)nc1
|
C18H23N3O4 345.399000 |
WLPDQZVMDHBCLH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594657; PubChem:CID146198307
|
Local ready
Direct docking supported
|
|
E3L029486
BDB029486
|
US11584748, Example 25
O=C1CCC2(CCN(C(=O)c3ccc4ncsc4c3)C2)C(=O)N1
|
C16H15N3O3S 329.381000 |
JWJJQVYGSHTVAA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594658; PubChem:CID146198280
|
Local ready
Direct docking supported
|
|
E3L029487
BDB029487
|
US11584748, Example 26
O=C1CCC2(CCN(C(=O)c3cc([N+](=O)[O-])ccn3)C2)C(=O)N1
|
C14H14N4O5 318.289000 |
LBTSCZBRPGZXSU-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594659; PubChem:CID146198243
|
Local ready
Direct docking supported
|
|
E3L029488
BDB029488
|
US11584748, Example 27
O=C1CCC2(CCN(C(=O)c3cccc4c3CC(=O)N4)C2)C(=O)N1
|
C17H17N3O4 327.340000 |
YAQOLPJWAQESJG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594660; PubChem:CID146198233
|
Local ready
Direct docking supported
|
|
E3L029489
BDB029489
|
US11584748, Example 28
COC(=O)c1ccc(C(=O)N2CCC3(CCC(=O)NC3=O)C2)cc1
|
C17H18N2O5 330.340000 |
JLAZTIKMMJQORM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594661; PubChem:CID146198242
|
Local ready
Direct docking supported
|
|
E3L029490
BDB029490
|
US11584748, Example 29
O=C1CCC2(CCN(C(=O)c3ccc4scnc4c3)C2)C(=O)N1
|
C16H15N3O3S 329.381000 |
CPYVPIQYEVTFQP-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594662; PubChem:CID146198246
|
Local ready
Direct docking supported
|
|
E3L029491
BDB029491
|
US11584748, Example 30
O=C1CCC2(CCN(c3ccc([N+](=O)[O-])cn3)C2)C(=O)N1
|
C13H14N4O4 290.279000 |
OFNBQRGXSDNUBC-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594663; PubChem:CID146198249
|
Local ready
Direct docking supported
|
|
E3L029492
BDB029492
|
US11584748, Example 31
CC(C(=O)N1CCC2(CCC(=O)NC2=O)C1)c1cccnc1
|
C16H19N3O3 301.346000 |
RWVKSCPEKGEEHN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594664; PubChem:CID146198271
|
Local ready
Direct docking supported
|
|
E3L029493
BDB029493
|
US11584748, Example 32
COC(=O)c1cccc(N2CCC3(CCC(=O)NC3=O)C2)n1
|
C15H17N3O4 303.318000 |
CLLLSNBLTMBAMO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594665; PubChem:CID146198245
|
Local ready
Direct docking supported
|
|
E3L029494
BDB029494
|
US11584748, Example 9
O=C1CCC2(CCN(c3nc4cc([N+](=O)[O-])ccc4[nH]3)C2)C(=O)N1
|
C15H15N5O4 329.316000 |
SRCDARZMFSKPJI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594666; PubChem:CID146198296
|
Local ready
Direct docking supported
|
|
E3L029495
BDB029495
|
US11584748, Example 9
O=C1CCC2(CCN(c3nc4cc([N+](=O)[O-])ccc4[nH]3)C2)C(=O)N1
|
C15H15N5O4 329.316000 |
SRCDARZMFSKPJI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594667; PubChem:CID146198296
|
Local ready
Direct docking supported
|
|
E3L029496
BDB029496
|
US11584748, Example 35
CC(=O)N1CCc2c(C(=O)N3CCC4(CCC(=O)NC4=O)C3)cccc21
|
C19H21N3O4 355.394000 |
BQTLTEWYIQQYDJ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594668; PubChem:CID146198247
|
Local ready
Direct docking supported
|
|
E3L029497
BDB029497
|
2-Benzoyl-2,7-diazaspiro[4.5]decane-6,8-dione
O=C1CCC2(CCN(C(=O)c3ccccc3)C2)C(=O)N1
|
C15H16N2O3 272.304000 |
YRFOPPHADOUNBS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594669; PubChem:CID146198257
|
Local ready
Direct docking supported
|
|
E3L029498
BDB029498
|
US11584748, Example 37
CC(=O)Nc1cccc(C(=O)N2CCC3(CCC(=O)NC3=O)C2)c1
|
C17H19N3O4 329.356000 |
BUGYAESNXFRINL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594670; PubChem:CID146198324
|
Local ready
Direct docking supported
|
|
E3L029499
BDB029499
|
US11584748, Example 38
O=C1CCC2(CCN(C(=O)c3cccc4[nH]ncc34)C2)C(=O)N1
|
C16H16N4O3 312.329000 |
IWRTVCYWLNFSLY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594671; PubChem:CID155790223
|
Local ready
Direct docking supported
|
|
E3L029500
BDB029500
|
US11584748, Example 39
Nc1ccc(N2CCC3(CCC(=O)NC3=O)C2)nc1
|
C13H16N4O2 260.297000 |
NBEUANPPZRTEPM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594672; PubChem:CID146198269
|
Local ready
Direct docking supported
|