| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L029461
BDB029461
|
US11572344, Example 31
N#Cc1ccc(C(=O)NOCC2CC2)c(Nc2ccc(I)cc2F)c1F
|
C18H14F2IN3O2 469.229000 |
PJNNUIQYQNFWEL-UHFFFAOYSA-N | Q13233 | Mitogen-activated protein kinase kinase kinase 1 |
BindingDB, PubChem
BindingDB:BDBM592190; PubChem:CID148915872
|
Local ready
Direct docking supported
|
|
E3L029462
BDB029462
|
2,7-Diazaspiro[4.5]decane-6,8-dione
O=C1CCC2(CCNC2)C(=O)N1
|
C8H12N2O2 168.196000 |
UKJXZGPIUGDZMZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594634; PubChem:CID146198232
|
Local ready
Direct docking supported
|
|
E3L029463
BDB029463
|
2-Methyl-2,7-diazaspiro[4.5]decane-3,6,8-trione
CN1CC2(CCC(=O)NC2=O)CC1=O
|
C9H12N2O3 196.206000 |
ZRMQZBRIJXPKNF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594635; PubChem:CID146198241
|
Local ready
Direct docking supported
|
|
E3L029464
BDB029464
|
US11584748, Example 3
O=C1CCC2(CCN(C(=O)Cc3ccccc3)C2)C(=O)N1
|
C16H18N2O3 286.331000 |
SIDOXLQSZYVHNB-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594636; PubChem:CID146198290
|
Local ready
Direct docking supported
|
|
E3L029465
BDB029465
|
US11584748, Example 4
O=C1CCC2(CCN(C(=O)C3CCc4ccccc43)C2)C(=O)N1
|
C18H20N2O3 312.369000 |
XFJHSVOOWQFIPY-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594637; PubChem:CID155790206
|
Local ready
Direct docking supported
|
|
E3L029466
BDB029466
|
US11584748, Example 5
O=C1CCC2(CCN(C(=O)c3cccc([N+](=O)[O-])c3)C2)C(=O)N1
|
C15H15N3O5 317.301000 |
GWZKPDNVILXNJL-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594638; PubChem:CID146198311
|
Local ready
Direct docking supported
|
|
E3L029467
BDB029467
|
US11584748, Example 6
COC(=O)c1ccc(N2CCC3(CCC(=O)NC3=O)C2)nc1
|
C15H17N3O4 303.318000 |
RPHRAKWJWNEBDE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594639; PubChem:CID146198277
|
Local ready
Direct docking supported
|
|
E3L029468
BDB029468
|
US11584748, Example 7
O=C1CCC2(CCN(c3nc4ncccc4s3)C2)C(=O)N1
|
C14H14N4O2S 302.359000 |
JAMNHMJDAVFPED-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594640; PubChem:CID146198297
|
Local ready
Direct docking supported
|
|
E3L029469
BDB029469
|
US11584748, Example 8
O=C1CCC2(CCN(c3ccc([N+](=O)[O-])cc3)C2)C(=O)N1
|
C14H15N3O4 289.291000 |
KVFAGCXJJHBNRS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594641; PubChem:CID146198268
|
Local ready
Direct docking supported
|
|
E3L029470
BDB029470
|
US11584748, Example 9
O=C1CCC2(CCN(c3nc4cc([N+](=O)[O-])ccc4[nH]3)C2)C(=O)N1
|
C15H15N5O4 329.316000 |
SRCDARZMFSKPJI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594642; PubChem:CID146198296
|
Local ready
Direct docking supported
|
|
E3L029471
BDB029471
|
US11584748, Example 9
O=C1CCC2(CCN(c3nc4cc([N+](=O)[O-])ccc4[nH]3)C2)C(=O)N1
|
C15H15N5O4 329.316000 |
SRCDARZMFSKPJI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594643; PubChem:CID146198296
|
Local ready
Direct docking supported
|
|
E3L029472
BDB029472
|
US11584748, Example 9
O=C1CCC2(CCN(c3nc4cc([N+](=O)[O-])ccc4[nH]3)C2)C(=O)N1
|
C15H15N5O4 329.316000 |
SRCDARZMFSKPJI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594644; PubChem:CID146198296
|
Local ready
Direct docking supported
|
|
E3L029473
BDB029473
|
US11584748, Example 12
O=C1CCC2(CCN(c3nc4ccccc4s3)C2)C(=O)N1
|
C15H15N3O2S 301.371000 |
YVQKTFGXZGHQOQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594645; PubChem:CID146198274
|
Local ready
Direct docking supported
|
|
E3L029474
BDB029474
|
US11584748, Example 13
COC(=O)c1cccc2nc(N3CCC4(CCC(=O)NC4=O)C3)[nH]c12
|
C17H18N4O4 342.355000 |
SUEVMGZZVJJGHO-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594646; PubChem:CID155790214
|
Local ready
Direct docking supported
|
|
E3L029475
BDB029475
|
US11584748, Example 14
COC(=O)c1ccnc(N2CCC3(CCC(=O)NC3=O)C2)n1
|
C14H16N4O4 304.306000 |
CKBLNQUDCJFUHI-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594647; PubChem:CID146198234
|
Local ready
Direct docking supported
|
|
E3L029476
BDB029476
|
US11584748, Example 15
O=C1CCC2(CCN(c3ccc4ccccc4n3)C2)C(=O)N1
|
C17H17N3O2 295.342000 |
FTIZPFZWQAOGSE-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594648; PubChem:CID146198254
|
Local ready
Direct docking supported
|
|
E3L029477
BDB029477
|
BDBM594649
Nc1ccc2nc(N3CCC4(CCC(=O)NC4=O)C3)sc2c1
|
C15H16N4O2S 316.386000 |
CAHYSQUJJHRKIN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594649; PubChem:CID146198264
|
Local ready
Direct docking supported
|
|
E3L029478
BDB029478
|
US11584748, Example 17
O=C1CCC2(CCN(c3nc4ncccc4o3)C2)C(=O)N1
|
C14H14N4O3 286.291000 |
RBPKZNCVPBQWFF-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594650; PubChem:CID146198276
|
Local ready
Direct docking supported
|
|
E3L029479
BDB029479
|
US11584748, Example 18
O=C1CCC2(CCN(c3nc4ccccc4o3)C2)C(=O)N1
|
C15H15N3O3 285.303000 |
QPVFUGHQRFQBHT-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594651; PubChem:CID146198258
|
Local ready
Direct docking supported
|
|
E3L029480
BDB029480
|
US11584748, Example 19
Cn1c(N2CCC3(CCC(=O)NC3=O)C2)nc2ccccc21
|
C16H18N4O2 298.346000 |
VDJWSRRLLLHXIK-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594652; PubChem:CID146198318
|
Local ready
Direct docking supported
|