| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L029501
BDB029501
|
US11584748, Example 40
O=C1CCC2(CCN(C(=O)c3cccc4c3CCN4)C2)C(=O)N1
|
C17H19N3O3 313.357000 |
PVPDVNLHCDQQKM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594673; PubChem:CID146198266
|
Local ready
Direct docking supported
|
|
E3L029502
BDB029502
|
US11584748, Example 41
O=C1CCC2(CCN(C(=O)c3ccc4c(c3)NCC4)C2)C(=O)N1
|
C17H19N3O3 313.357000 |
AMEXKYIPQUJWAX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594674; PubChem:CID146198282
|
Local ready
Direct docking supported
|
|
E3L029503
BDB029503
|
US11584748, Example 42
CC(=O)N1CCc2ccc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)cc21
|
C19H21N3O4 355.394000 |
RXIXLYAWKJONSZ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594675; PubChem:CID146198275
|
Local ready
Direct docking supported
|
|
E3L029504
BDB029504
|
US11584748, Example 43
CC(=O)Nc1ccc(N2CCC3(CCC(=O)NC3=O)C2)nc1
|
C15H18N4O3 302.334000 |
JTPHDUQRXRKFJN-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594676; PubChem:CID155790117
|
Local ready
Direct docking supported
|
|
E3L029505
BDB029505
|
US11584748, Example 44
O=C1CCC2(CCN(C(=O)c3coc4ccccc34)C2)C(=O)N1
|
C17H16N2O4 312.325000 |
RVZINIOIHXQATH-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594677; PubChem:CID146198286
|
Local ready
Direct docking supported
|
|
E3L029506
BDB029506
|
US11584748, Example 45
O=C1CCC2(CCN(C(=O)c3cnn4ccccc34)C2)C(=O)N1
|
C16H16N4O3 312.329000 |
GCIDAANCMJYVRS-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594678; PubChem:CID146198291
|
Local ready
Direct docking supported
|
|
E3L029507
BDB029507
|
US11584748, Example 46
O=C1CCC2(CCN(C(=O)c3ccc4ncoc4c3)C2)C(=O)N1
|
C16H15N3O4 313.313000 |
CHXPPHPYGXLZEX-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594679; PubChem:CID146198259
|
Local ready
Direct docking supported
|
|
E3L029508
BDB029508
|
US11584748, Example 47
O=C1CCC2(CCN(C(=O)c3ccc4c(c3)CCN4)C2)C(=O)N1
|
C17H19N3O3 313.357000 |
SVKXTJNJMXAWJR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594680; PubChem:CID146198238
|
Local ready
Direct docking supported
|
|
E3L029509
BDB029509
|
US11584748, Example 48
O=C1CCC2(CCN(C(=O)[C@@H]3CCCc4ccccc43)C2)C(=O)N1
|
C19H22N2O3 326.396000 |
SJGZOAXXBOLPGG-NYRJJRHWSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594681; PubChem:CID146198317
|
Local ready
Direct docking supported
|
|
E3L029510
BDB029510
|
US11584748, Example 49
O=C1CCC2(CCN(C(=O)[C@H]3CCCc4ccccc43)C2)C(=O)N1
|
C19H22N2O3 326.396000 |
SJGZOAXXBOLPGG-FUKCDUGKSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594682; PubChem:CID146198294
|
Local ready
Direct docking supported
|
|
E3L029511
BDB029511
|
US11584748, Example 50
CC(=O)Nc1nc2cc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)ccc2s1
|
C18H18N4O4S 386.433000 |
MXYRZLUNWIJXOA-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594683; PubChem:CID155790185
|
Local ready
Direct docking supported
|
|
E3L029512
BDB029512
|
US11584748, Example 51
CC(=O)Nc1nc2ccc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)cc2s1
|
C18H18N4O4S 386.433000 |
FDUBYROGCOUTID-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594684; PubChem:CID155790236
|
Local ready
Direct docking supported
|
|
E3L029513
BDB029513
|
US11584748, Example 52
CC(=O)N1CCc2cc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)ccc21
|
C19H21N3O4 355.394000 |
HCECPOGXPNPDHR-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594685; PubChem:CID155790233
|
Local ready
Direct docking supported
|
|
E3L029514
BDB029514
|
US11584748, Example 53
CC(C)(C)OC(=O)Nc1nc2cc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)ccc2s1
|
C21H24N4O5S 444.513000 |
HAQPWPLXJGYWRM-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594686; PubChem:CID155790130
|
Local ready
Direct docking supported
|
|
E3L029515
BDB029515
|
US11584748, Example 54
CC(C)(C)OC(=O)Nc1nc2ccc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)cc2s1
|
C21H24N4O5S 444.513000 |
JUNFVLSSUQLUHG-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594687; PubChem:CID155790182
|
Local ready
Direct docking supported
|
|
E3L029516
BDB029516
|
US11584748, Example 55
Nc1nc2ccc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)cc2s1
|
C16H16N4O3S 344.396000 |
WKSVZNDGRMOYLD-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594688; PubChem:CID146198248
|
Local ready
Direct docking supported
|
|
E3L029517
BDB029517
|
US11584748, Example 57
Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=N[C@@H](CC(=O)NCCCCCCCC(=O)Nc1cccc(C(=O)N3CCC4(CCC(=O)NC4=O)C3)c1)c1nnc(C)n1-2
|
C42H47ClN8O5S 811.409000 |
YDJFNASTIGGGBC-MUAQNSFOSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594690; PubChem:CID156047434
|
Local ready
Direct docking supported
|
|
E3L029518
BDB029518
|
US11584748, Example 58
O=C1NC(=O)C2(CCN(C(=O)[C@H]3CCCc4ccccc43)CC2)N1
|
C18H21N3O3 327.384000 |
AQBJULSTCREMNI-AWEZNQCLSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594691; PubChem:CID93988802
|
Local ready
Direct docking supported
|
|
E3L029519
BDB029519
|
US11584748, Example 59
O=C1NC(=O)C2(CCN(C(=O)[C@@H]3CCCc4ccccc43)CC2)N1
|
C18H21N3O3 327.384000 |
AQBJULSTCREMNI-CQSZACIVSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594692; PubChem:CID93988803
|
Local ready
Direct docking supported
|
|
E3L029520
BDB029520
|
8-Benzoyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
O=C1NC(=O)C2(CCN(C(=O)c3ccccc3)CC2)N1
|
C14H15N3O3 273.292000 |
XMSIVKKCIHEDJQ-UHFFFAOYSA-N | Q96SW2 | Protein cereblon |
BindingDB, PubChem
BindingDB:BDBM594693; PubChem:CID42109422
|
Local ready
Direct docking supported
|