| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L031461
BDB031461
|
BDBM628667
CCC(O)CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H27Cl2FN2O4 533.427000 |
SJYMHFBUIRADQJ-IAIRZMIISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628667; PubChem:CID135282607
|
Local ready
Direct docking supported
|
|
E3L031462
BDB031462
|
BDBM628669
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OC1CCCC1CO)c1ccc(Cl)cc1
|
C30H29ClFN3O4 550.030000 |
HLRLKTCARZAWTF-KIKFKFQISA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628669
|
Local ready
Direct docking supported
|
|
E3L031463
BDB031463
|
BDBM628670
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@H]1CCOC1)c1ccc(Cl)cc1
|
C27H25Cl2FN2O4 531.411000 |
NDAPOVHOUFFWHD-KDYSTLNUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628670; PubChem:CID135282842
|
Local ready
Direct docking supported
|
|
E3L031464
BDB031464
|
BDBM628671
C[C@@H](c1ccc(Cl)cn1)N1C(=O)c2cc(C(C)(C)O)cc(F)c2[C@]1(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1
|
C29H28Cl2FN3O4 572.464000 |
AFEWMFCKKMSZMK-GUNSETOZSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628671
|
Local ready
Direct docking supported
|
|
E3L031465
BDB031465
|
BDBM628672
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(O[C@@H]1CCOC1)c1ccc(Cl)cc1
|
C27H25Cl2FN2O4 531.411000 |
NDAPOVHOUFFWHD-JIPXPUAJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628672; PubChem:CID135282853
|
Local ready
Direct docking supported
|
|
E3L031466
BDB031466
|
BDBM628673
C[C@H](c1ccc(Cl)cn1)N1C(=O)c2cc(C(C)(C)O)cc(F)c2[C@]1(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1
|
C29H28Cl2FN3O4 572.464000 |
AFEWMFCKKMSZMK-HYDGNGQDSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628673
|
Local ready
Direct docking supported
|
|
E3L031467
BDB031467
|
BDBM628674
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OC1CCCC1O)c1ccc(Cl)cc1
|
C29H27ClFN3O4 536.003000 |
GWAQZINJCFWPQB-KZNPQIALSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628674; PubChem:CID135282890
|
Local ready
Direct docking supported
|
|
E3L031468
BDB031468
|
BDBM628675
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)c3ccncc3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H23Cl2N3O3 520.416000 |
IZZIJJDFJQZLMF-PLYLYKGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628675; PubChem:CID135282472
|
Local ready
Direct docking supported
|
|
E3L031469
BDB031469
|
BDBM628677
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)c3cncnc3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H22Cl2N4O3 521.404000 |
JIPHZCROEAMAKP-SSYAZFEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628677; PubChem:CID135282722
|
Local ready
Direct docking supported
|
|
E3L031470
BDB031470
|
BDBM628679
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3CCNCC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H30Cl2N4O3 541.479000 |
FJDMEZFROWWKKM-PLYLYKGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628679; PubChem:CID135282381
|
Local ready
Direct docking supported
|
|
E3L031471
BDB031471
|
BDBM628680
CNC(=O)C1(CO[C@]2(c3ccc(Cl)cc3)c3c(F)cc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cn2)CC1
|
C29H28Cl2FN3O4 572.464000 |
XRCTXOPCGZZSRW-GDLZYMKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628680
|
Local ready
Direct docking supported
|
|
E3L031472
BDB031472
|
BDBM628681
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)C3CCN(C(C)=O)CC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C30H31Cl2N3O4 568.501000 |
BPTDTCZXHGEFDP-BDCODIICSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628681; PubChem:CID135282285
|
Local ready
Direct docking supported
|
|
E3L031473
BDB031473
|
BDBM628683
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CNC3CC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H27Cl2N3O3 512.437000 |
IPTTWPFOGWKHQX-SSYAZFEXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628683; PubChem:CID135282668
|
Local ready
Direct docking supported
|
|
E3L031474
BDB031474
|
BDBM628684
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CN3CCOCC3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H29Cl2N3O4 542.463000 |
ITHUXMWFHOVPTD-PLYLYKGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628684; PubChem:CID135282652
|
Local ready
Direct docking supported
|
|
E3L031475
BDB031475
|
BDBM628686
CNCC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OC)c1ccc(Cl)cc1
|
C25H25Cl2N3O3 486.399000 |
ZQYCKQISNWAOKW-WUBHUQEYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628686; PubChem:CID135282637
|
Local ready
Direct docking supported
|
|
E3L031476
BDB031476
|
BDBM628688
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)CNC(C)=O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C26H25Cl2N3O4 514.409000 |
LQUNNAHDMRTLOQ-FXDYGKIASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628688; PubChem:CID135282665
|
Local ready
Direct docking supported
|
|
E3L031477
BDB031477
|
BDBM628689
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(C(N)=O)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C32H32Cl2FN3O5 628.528000 |
RMZFDMZVKKYNEH-BDJZEIKTSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628689
|
Local ready
Direct docking supported
|
|
E3L031478
BDB031478
|
BDBM628690
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(N)CC1)c1ccc(Cl)cc1
|
C27H26Cl2FN3O3 530.427000 |
ZTWLWISKQGJFCE-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628690; PubChem:CID135282507
|
Local ready
Direct docking supported
|
|
E3L031479
BDB031479
|
BDBM628691
CC(O)(c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1)C1CCOCC1
|
C33H33ClFN3O5 606.094000 |
TWMPEOLEJLTRSB-NFCCVXSLSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628691
|
Local ready
Direct docking supported
|
|
E3L031480
BDB031480
|
BDBM628695
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OC1CC(O)C1)c1ccc(Cl)cc1
|
C28H25ClFN3O4 521.976000 |
IOLBLHPDUMCCDS-CBIUGAAKSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628695; PubChem:CID135282399
|
Local ready
Direct docking supported
|