| Compound ID | Name | Formula / MW | InChIKey | E3 | Target | Source | Docking structure |
|---|---|---|---|---|---|---|---|
|
E3L031441
BDB031441
|
BDBM628642
CC1CC1(O)[C@@]1(c2ccc(Cl)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(C#N)cn1
|
C28H26ClN3O3 487.987000 |
HLOMIXXULDOGGM-YKJFFMCESA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628642
|
Local ready
Direct docking supported
|
|
E3L031442
BDB031442
|
BDBM628643
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OC1CCC(O)C1)c1ccc(Cl)cc1
|
C29H27ClFN3O4 536.003000 |
OUJSBTNQZXSBCL-RZRYPWFSSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628643; PubChem:CID135282591
|
Local ready
Direct docking supported
|
|
E3L031443
BDB031443
|
BDBM628645
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(O[C@H]1CC[C@@H](O)C1)c1ccc(Cl)cc1
|
C29H27ClFN3O4 536.003000 |
OUJSBTNQZXSBCL-RLPNJSHFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628645
|
Local ready
Direct docking supported
|
|
E3L031444
BDB031444
|
BDBM628646
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(O[C@@H]1CC[C@H](O)C1)c1ccc(Cl)cc1
|
C29H27ClFN3O4 536.003000 |
OUJSBTNQZXSBCL-QFWOEDSFSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628646
|
Local ready
Direct docking supported
|
|
E3L031445
BDB031445
|
BDBM628647
COc1ccc(CN2C(=O)c3cc(C(C)(C)O)cc(F)c3[C@]2(c2ccc(Cl)cc2)C2(O)CC2C)cn1
|
C28H28ClFN2O4 510.993000 |
AMPKEICOGLLZKE-LZIYAXBJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628647
|
Local ready
Direct docking supported
|
|
E3L031446
BDB031446
|
BDBM628648
CC1CC1(O)[C@@]1(c2ccc(C(F)(F)F)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H26ClF3N2O3 530.974000 |
TZQROAAKTUVNLJ-PUVSLQQJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628648
|
Local ready
Direct docking supported
|
|
E3L031447
BDB031447
|
BDBM628649
CC(C)(O)CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H28Cl2N2O4 515.437000 |
VODYQLSIAFFNDN-HHHXNRCGSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628649; PubChem:CID135282871
|
Local ready
Direct docking supported
|
|
E3L031448
BDB031448
|
BDBM628650
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(C(C)(F)F)cc1
|
C30H31ClF2N2O4 557.037000 |
DPZSKMQSQBPFQZ-SSEXGKCCSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628650; PubChem:CID135282880
|
Local ready
Direct docking supported
|
|
E3L031449
BDB031449
|
BDBM628651
CC1CC1(O)[C@@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(O)CN(C)C)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C29H30Cl2FN3O3 558.481000 |
LOVPUPSVKYLVSW-AJWARCIRSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628651
|
Local ready
Direct docking supported
|
|
E3L031450
BDB031450
|
BDBM628653
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C29H27ClFN3O4 536.003000 |
GDVBWGYVVZIZIR-GDLZYMKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628653
|
Local ready
Direct docking supported
|
|
E3L031451
BDB031451
|
BDBM628654
CC1(CO[C@]2(c3ccc(Cl)cc3)c3ccc(C(C)(C)O)cc3C(=O)N2Cc2ccc(Cl)cn2)COC1
|
C28H28Cl2N2O4 527.448000 |
RPIRIRKCKKYWFK-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628654; PubChem:CID135282077
|
Local ready
Direct docking supported
|
|
E3L031452
BDB031452
|
BDBM628655
Cc1ccc(CN2C(=O)c3cc(C(C)(C)O)cc(F)c3[C@]2(OCC2(CO)CC2)c2ccc(Cl)cc2)nc1
|
C29H30ClFN2O4 525.020000 |
CZSJGQSSBQIPSN-GDLZYMKVSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628655
|
Local ready
Direct docking supported
|
|
E3L031453
BDB031453
|
BDBM628656
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)c3cn[nH]c3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C26H22Cl2N4O3 509.393000 |
UEAWYDNNRRPTDL-FXDYGKIASA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628656; PubChem:CID135282144
|
Local ready
Direct docking supported
|
|
E3L031454
BDB031454
|
BDBM628658
CC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ncc(Cl)cn1)C2(OCC1(CO)CC1)c1ccc(Cl)cc1
|
C27H26Cl2FN3O4 546.426000 |
STWVXRJINHBPQY-UHFFFAOYSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628658; PubChem:CID137497996
|
Local ready
Direct docking supported
|
|
E3L031455
BDB031455
|
BDBM628659
COCC(C)(O)c1cc(F)c2c(c1)C(=O)N(Cc1ccc(Cl)cn1)[C@@]2(c1ccc(Cl)cc1)C1(O)CC1C
|
C28H27Cl2FN2O4 545.438000 |
PDDZMZJKQJSSKF-KUXJFXKNSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628659
|
Local ready
Direct docking supported
|
|
E3L031456
BDB031456
|
BDBM628661
CC(CO)(CO)CO[C@]1(c2ccc(Cl)cc2)c2c(F)cc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H29Cl2FN2O5 563.453000 |
LUNMBGSAQSJZDI-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628661
|
Local ready
Direct docking supported
|
|
E3L031457
BDB031457
|
BDBM628662
CC1CC1(O)[C@@]1(c2ccc(F)c(F)c2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C27H25ClF2N2O3 498.957000 |
YRFIWMILOQMFON-KDCDNYMMSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628662
|
Local ready
Direct docking supported
|
|
E3L031458
BDB031458
|
BDBM628663
CC(C)(O)c1ccc2c(c1)C(=O)N(Cc1ccc(C#N)cn1)[C@@]2(OCC1CC1)c1ccc(Cl)cc1
|
C28H26ClN3O3 487.987000 |
BFVAJJVCZAUQCA-MUUNZHRXSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628663; PubChem:CID135282533
|
Local ready
Direct docking supported
|
|
E3L031459
BDB031459
|
BDBM628664
CO[C@]1(c2ccc(Cl)cc2)c2ccc(C(C)(O)c3cccnc3)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H23Cl2N3O3 520.416000 |
FMMQKZNXTAISDK-PLYLYKGUSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB, PubChem
BindingDB:BDBM628664; PubChem:CID135283094
|
Local ready
Direct docking supported
|
|
E3L031460
BDB031460
|
BDBM628666
CC1CC1(O)[C@@]1(c2ccc(OC(F)(F)F)cc2)c2ccc(C(C)(C)O)cc2C(=O)N1Cc1ccc(Cl)cn1
|
C28H26ClF3N2O4 546.973000 |
BWISTIXXHGVURN-PUVSLQQJSA-N | Q00987 | E3 ubiquitin-protein ligase Mdm2 |
BindingDB
BindingDB:BDBM628666
|
Local ready
Direct docking supported
|